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Experimental Malignant Hyperthermia


Experimental Malignant Hyperthermia
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Experimental Malignant Hyperthermia


Experimental Malignant Hyperthermia
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Author : Charles H. Williams
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Experimental Malignant Hyperthermia written by Charles H. Williams and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Malignant hyperthermia is a genetic disease that causes an extremely high body temperature. The syndrome is triggered by depolarizing muscle relaxants and halogenated gaseous anesthetics, such as halothane. The purpose of the book is to present the latest experimental work and important conclusions to anesthesiologists, surgeons, certified registered nurse anesthesists, operating nurses, cardiovascular and temperature oriented physiologists, basic research scientists interested in heat production in muscle, animal scientists, primarily swine physiologists, and finally, muscle biology scientists. The results are based on sixteen years of experimental investigations with a malignant hyperthermia susceptible pig colony. Consequently, the data and conclusions are more concrete than the clinical data from human patients. The first five chapters present fresh material relating to the detailed biochemical mechanism of heat production during malignant hyperthermia. Subsequent chapters present recent data on malignant hyperthermia in horses and dogs; these additional animal models provide useful material for future studies of malignant hyperthermia pathophysiology. Later sections summarize the laboratory methods currently used for diagnosing malignant hyperthermia in human patients and present valuable data on malignant hyperthermia in the greater Kansas city area over a twenty year period.



Experimental Malignant Hyperthermia


Experimental Malignant Hyperthermia
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Author : Charles H Williams
language : en
Publisher:
Release Date : 1987-12-01

Experimental Malignant Hyperthermia written by Charles H Williams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-12-01 with categories.




Malignant Hyperthermia


Malignant Hyperthermia
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Author : S. Tsuyoshi Ohnishi
language : en
Publisher: CRC Press
Release Date : 2022-04-18

Malignant Hyperthermia written by S. Tsuyoshi Ohnishi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-18 with Medical categories.


This book is dedicated to those who died of malignant hyperthermia and to their families. It contains cases studies that would be helpful for anesthesiologists, surgeons, physiologists, molecular biologists, biophysicists, biochemists, pathologists, students, and post doctoral fellows.



Cumulated Index Medicus


Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1991

Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.




Anesthesiology Second Edition


Anesthesiology Second Edition
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Author : David E. Longnecker
language : en
Publisher: McGraw Hill Professional
Release Date : 2012-05-23

Anesthesiology Second Edition written by David E. Longnecker and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-23 with Medical categories.


Accompanying DVD-ROM contains ... "an image gallery and video clips of key procedures."--P. [4] of cover.



National Library Of Medicine Current Catalog


National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1988

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medicine categories.




Advances In Food Research


Advances In Food Research
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Author :
language : en
Publisher: Academic Press
Release Date : 1983-01-11

Advances In Food Research written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-01-11 with Technology & Engineering categories.


Advances in Food Research



Toxicity Bibliography


Toxicity Bibliography
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Author :
language : en
Publisher:
Release Date : 1875

Toxicity Bibliography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1875 with Drugs categories.




Mechanisms Of Anesthetic Action In Skeletal Cardiac And Smooth Muscle


Mechanisms Of Anesthetic Action In Skeletal Cardiac And Smooth Muscle
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Author : Thomas J.J. Blanck
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mechanisms Of Anesthetic Action In Skeletal Cardiac And Smooth Muscle written by Thomas J.J. Blanck and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The volatile anesthetics continue to be one of the most mysterious yet commonly used class of drugs in medical practice today. A prominent and troublesome side effect of volatile anesthetics is their ability to alter hemodynamics. This arises from two diverse but interrelated phenomena, depression of cardiac contractility and dilation of the vasculature. These effects of volatile anesthetics on cardiac and smooth muscle plus the action of volatile anesthetics on skeletal muscle in the malignant hyperthermic syndrome have led to concern about the interaction of volatile anesthetics (and other anesthetic agents) with calcium metabolism in the muscle cell. Many of the phenomena caused by anesthetics appear to have common mechanisms in all of the muscle types; however, the differences among skeletal, cardiac and smooth muscle also lead to distinct effects of the anesthetics in each. Given the diverse research disciplines which have been brought to hear on the mechanism of anesthetic alteration of contractility, the symposium from which this book originates was convened for the purpose of gathering those with common interests in anesthetic agents and their cellular and subcellular actions in muscle. The recent symposium had its origins in a small but exciting meeting that took place at the University of Texas at Houston in 1984. At that time, Robert Merin and Jacques Chelly convened a group of people who had interest in cardiac muscle and calcium antagonists.



Malignant Hyperthermia


Malignant Hyperthermia
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Author : Michio Morio
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Malignant Hyperthermia written by Michio Morio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


In susceptible individuals, malignant hyperthermia (MH) can be triggered by various anesthetics during surgery. First described in 1960, research since then has concentrated on reducing the very high mortality rate associated with MH. Although significant progress in treatment has been made with the introduction of dantrolene sodium in 1979, many questions remain unanswered. Following on the results of more than 30 years of investigative efforts, the Third International Symposium on MH was held in Hiroshima, Japan, in 1994, immediately before the Seventh International Workshop on MH. Specialists in the field discussed the most up-to-date findings from the point of view of clinical classification, history, and incidence based on the evidence of epidemiology, diagnostic muscle testing, genetics, and biochemistry. These proceedings of the symposium present important keys to understanding the mechanism of MH and related syndromes at the genetic level and include procedures for the monitoring and care of patients. This volume will be invaluable not only for surgeons and anesthesiologists but also for physiologists and researchers.