Experimental Neurosurgery In Animal Models
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Experimental Neurosurgery In Animal Models
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Author : Miroslaw Janowski
language : en
Publisher: Neuromethods
Release Date : 2018-06-22
Experimental Neurosurgery In Animal Models written by Miroslaw Janowski and has been published by Neuromethods this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-22 with Medical categories.
This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.
Research And Publishing In Neurosurgery
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Author : Yücel Kanpolat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Research And Publishing In Neurosurgery written by Yücel Kanpolat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
"Research” and "Publishing” are phrases familiar to all neurosurgeons and neuroscientists. Many young neurosurgeons struggle with them on a trial-and-error basis at first, and there are not structured education programs providing information on standard methods. The European Association of Neurosurgical Societies Research Committee has developed a course on research and publication methods for residents in neurosurgery who have not yet completed training. This supplement includes selected contributions from this course and will serve as an essential handbook providing basic tools to guide research and publication work, presenting time-saving advice, and resulting in the most beneficial contributions in experimental and clinical research.
Brain Stimulation
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Author : Yasin Temel
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-11
Brain Stimulation written by Yasin Temel and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Deep brain stimulation (DBS) as a therapy in neurological and psychiatric disorders is applied widely. In this respect, DBS in animal models is performed to study the underlying mechanisms and to evaluate new indications and technology. This chapter summarizes our experience with DBS in animal models, and relevant literature. Electrodes for DBS in animal models have been developed using translational principles, to allow DBS under anesthesia and in freely moving conditions. The stimulation parameters have been adjusted for the animals using current density calculations. This paradigm of experimental DBS has been validated in a variety of animal models of neurological and psychiatric disorders. During the process of development and validation of DBS in animal models, specific problems have been encountered, which are discussed in the chapter. DBS in animal models is an adequate paradigm to explore the underlying mechanisms and new indications for DBS, and to refine DBS technology.
Step By Step Experimental Pinealectomy Techniques In Animals For Researchers
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Author : Mehmet Turgut
language : en
Publisher: Nova Science Publishers
Release Date : 2013
Step By Step Experimental Pinealectomy Techniques In Animals For Researchers written by Mehmet Turgut and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Anatomy categories.
This book contains a varied collection of chapters covering pinealectomy techniques used in current neuroscience research from over 19 internationally recognised scientists. In a total of 8 chapters, this book presents general information in pinealectomy covering topics from anatomy and histology of the pineal gland in animals to the melatonin system and different surgical techniques. This book forms an essential reference for anyone working in neuroscience, from beginner students to experienced researchers since basic information on different pinealectomy procedures used in animal models can be extremely hard to find.
Step By Step Experimental Pinealectomy Techniques In Animals For Researchers
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Author : Mehmet Turgut
language : en
Publisher: Nova Biomedical Books
Release Date : 2014-05-14
Step By Step Experimental Pinealectomy Techniques In Animals For Researchers written by Mehmet Turgut and has been published by Nova Biomedical Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Medical categories.
This book contains a varied collection of chapters covering pinealectomy techniques used in current neuroscience research from over 19 internationally recognized scientists. In a total of 8 chapters, this book presents general information in pinealectomy covering topics from anatomy and histology of the pineal gland in animals to the melatonin system and different surgical techniques. This book forms an essential reference for anyone working in neuroscience, from beginner students to experienced researchers since basic information on different pinealectomy procedures used in animal models can be extremely hard to find.
Experimental Gene Therapy In Animal Models Of Neurological Diseases
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Author : Graham Morrissey
language : en
Publisher:
Release Date : 2001
Experimental Gene Therapy In Animal Models Of Neurological Diseases written by Graham Morrissey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Animal Models Of Acute Neurological Injuries
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Author : Jun Chen
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-16
Animal Models Of Acute Neurological Injuries written by Jun Chen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-16 with Medical categories.
Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
Animal Models And The Unity Of Neuroscience
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Author : Nina A. Atanasova
language : en
Publisher:
Release Date : 2014
Animal Models And The Unity Of Neuroscience written by Nina A. Atanasova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Contemporary neurobiology abounds with multiple experimental protocols and procedures aiming to study identical phenomena. This state of affairs seems to put in jeopardy the integration of experimental results and the extrapolation of laboratory knowledge to natural world phenomena. The problem is further complicated when knowledge produced through animal experimentation is extended to humans. My thesis is that the multiplicity of protocols fosters rather than precludes progress in neurobiology. It is especially valued when the results of different experiments converge. In these cases, the validity of knowledge claims increases. Converging experimental results get integrated. To date, no comprehensive philosophical analysis of animal experimentation in neurobiology exists. For this reason I analyze the functions of animal models in experimental neurobiology. I argue that even though animal models are related to model and experimental organisms, in the case of neurobiology, they are better conceptualized as experimental systems rather than as a subclass of the other two classes of biological models. In a case study, I trace the developments of and the variations on the basic design of Morris water maze experiments to exemplify the motivation for producing variations on basic experimental protocols. Ultimately, I defend a view of the structure of experimental neurobiology which I call optimistic pluralism. It is an extension of the so called perspectival pluralism according to which the integration of multiple partial perspectives employed in the study of any given phenomenon maximizes the knowledge about this phenomenon. It is optimistic because it justifies the possibility for multiple partial perspectives to converge and be integrated in order to provide knowledge about complex phenomena. This view justifies the desirability of multiple experimental protocols in contemporary neurobiology because it values the multiplicity of perspectives they provide.
Molecular Neurosurgery With Targeted Toxins
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Author : Ronald G. Wiley
language : en
Publisher: Humana Press
Release Date : 2010-12-16
Molecular Neurosurgery With Targeted Toxins written by Ronald G. Wiley and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-16 with Medical categories.
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.
International Animal Research Regulations
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-06-26
International Animal Research Regulations written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-26 with Science categories.
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.