[PDF] Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models - eBooks Review

Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models


Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models
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Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models


Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models
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Author : Lifeng Zhu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-04-07

Exploring The Influence Of Gut Microbiome On Human Health Mechanistic Insights From Pig Models written by Lifeng Zhu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-07 with Science categories.


The microbiome plays an indispensable role in our health. Pathophysiological alterations in the gut microbiota has been linked with the development and maintenance of non-communicable diseases, such as obesity, cancer, type 2 diabetes mellitus, cardiovascular diseases, and metabolic syndrome. In order to better investigate the interactions between human health/disease and microbiota and given the practical and ethical complexity of performing invasive sampling procedures in human subjects, different types of animal models have been developed and are frequently used to investigate the multiple dynamics of host–microbiome interactions. Due to the similar organ size and similar metabolic characteristics of pigs and humans, pigs are considered to be a more suitable model for basic biomedical research studies and for studying human-related metabolic diseases than rodents. The anatomical characters, physiological traits, genetics and biochemical indices of pigs are similar to what is reported in humans, thus, pig can be used as a model animal to characterize human gut microbiota and for studying several human diseases. The swine intestinal tract harbours trillions of diverse microorganisms, which get involved in regulating host nutrient digestion, energy absorption, and disease development, and is considered to be one of the main model animal of human obesity and disease research. Since the gastrointestinal organs of pigs are closer to humans, we also use pigs as a model for studying the role of functional foods in intestinal pathophysiology and related indicators of the physical barrier, biochemical barrier, immunological barrier and gut microbiota. Pigs are also the best animal models for exploring the mechanisms underlying human nutrient digestion and absorption, metabolism, and disease treatment. Large animal models such as piglets have been also used to study neonatal diet impact on gut, microbiota and immune system. Pigs and piglets are also convenient models for exploring avenues for developing novel microbial therapies. Pigs and piglets represent hence some of the most widely used animal models for studying the impact of microbiota on its host, and for exploring the dynamics of host–gut microbiome interactions and the roles of human gut microbiota in human health and disease development.



Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease


Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease
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Author : Mark Lyte
language : en
Publisher: Springer
Release Date : 2014-07-05

Microbial Endocrinology The Microbiota Gut Brain Axis In Health And Disease written by Mark Lyte and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-05 with Science categories.


The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​



The Impact Of Food Bioactives On Health


The Impact Of Food Bioactives On Health
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Author : Kitty Verhoeckx
language : en
Publisher: Springer
Release Date : 2015-04-29

The Impact Of Food Bioactives On Health written by Kitty Verhoeckx and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-29 with Technology & Engineering categories.


“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.



Microbiome Host Interactions


Microbiome Host Interactions
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Author : D. Dhanasekaran
language : en
Publisher: CRC Press
Release Date : 2021-04-01

Microbiome Host Interactions written by D. Dhanasekaran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-01 with Medical categories.


Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences



Microbiome In Human Health And Disease


Microbiome In Human Health And Disease
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Author : Pallaval Veera Bramhachari
language : en
Publisher: Springer Nature
Release Date : 2021-10-18

Microbiome In Human Health And Disease written by Pallaval Veera Bramhachari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-18 with Medical categories.


The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.



Interactions Between Bioactive Food Ingredients And Intestinal Microbiota


Interactions Between Bioactive Food Ingredients And Intestinal Microbiota
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Author : Zheng Ruan
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-06

Interactions Between Bioactive Food Ingredients And Intestinal Microbiota written by Zheng Ruan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-06 with Science categories.




Probiotic Dairy Products


Probiotic Dairy Products
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Author : Adnan Y. Tamime
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-05

Probiotic Dairy Products written by Adnan Y. Tamime and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-05 with Technology & Engineering categories.


Probiotic Dairy Products, 2nd Edition The updated guide to the most current research and developments in probiotic dairy products The thoroughly revised and updated second edition of Probiotic Dairy Products reviews the recent advancements in the dairy industry and includes the latest scientific developments in regard to the 'functional' aspects of dairy and fermented milk products and their ingredients. Since the publication of the first edition of this text, there have been incredible advances in the knowledge and understanding of the human microbiota, mainly due to the development and use of new molecular analysis techniques. This new edition includes information on the newest developments in the field. It offers information on the new ‘omic’ technologies that have been used to detect and analyse all the genes, proteins and metabolites of individuals’ gut microbiota. The text also includes a description of the history of probiotics and explores the origins of probiotic products and the early pioneers in this field. Other chapters in this resource provide valuable updates on genomic analysis of probiotic strains and aspects of probiotic products’ production and quality control. This important resource: Offers a completely revised and updated edition to the text that covers the topic of probiotic dairy products Contains 4 brand new chapters on the following topics: the history of probiotics, prebiotic components, probiotic research, and the production of vitamins, exopolysaccharides (EPS), and bacteriocins Features a new co-editor and a host of new contributors, that offer the latest research findings and expertise Is the latest title in Wiley's Society of Dairy Technology Technical Series Probiotic Dairy Products is an essential resource for dairy scientists, dairy technologists and nutritionists. The text includes the results of the most reliable research in field and offers informed views on the future of, and barriers to, the progress for probiotic dairy products.



Calcium In Human Health


Calcium In Human Health
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Author : Connie M. Weaver
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-10

Calcium In Human Health written by Connie M. Weaver and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-10 with Medical categories.


The Nutrition and Health Series of books have had great success because each volume has the consistent overriding mission of providing health professionals with texts that are essential because each includes (1) a synthesis of the state of the science; (2) timely, in-depth reviews by the leading researchers in their respective fields; (3) extensive, - to-date fully annotated reference lists; (4) a detailed index; (5) relevant tables and figures; (6) identification of paradigm shifts and the consequences; (7) virtually no overlap of information between chapters, but targeted, interchapter referrals; (8) suggestions of areas for future research; and (9) balanced, data-driven answers to patient/health prof- sionals’ questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose trainings are both research- and practice-oriented, have the opportunity to develop a primary objective for their book; define the scope and focus, and then invite the leading authorities from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research findings to potential human health consequences.



Handbook Of Life Course Health Development


Handbook Of Life Course Health Development
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Author : Neal Halfon
language : en
Publisher: Springer
Release Date : 2017-11-20

Handbook Of Life Course Health Development written by Neal Halfon and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-20 with Medical categories.


This book is open access under a CC BY 4.0 license. ​This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.



Evolving Mechanisms Of Disease Tolerance


Evolving Mechanisms Of Disease Tolerance
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Author : Maziar Divangahi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-03

Evolving Mechanisms Of Disease Tolerance written by Maziar Divangahi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-03 with categories.