Extraction Of Capsaicin Formulation And Evaluation Of A Transdermal Patch

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Extraction Of Capsaicin Formulation And Evaluation Of A Transdermal Patch

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Author : Simachal Panda
language : en
Publisher: Deep Science Publishing
Release Date : 2024-11-21

Extraction Of Capsaicin Formulation And Evaluation Of A Transdermal Patch written by Simachal Panda and has been published by Deep Science Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Medical categories.

Ethyl ester prodrug of non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor capsaicinat is the proposed model drug capsaicin. These hypothesized TDDs managed ventricular arrhythmias and had short biological half-life, low oral bioavailability, dosage, and molecular weight for better drug absorption. The suggested transdermal patch combines a slow-release calcium channel blocker with a sustained-release capsaicin angiotensin converting enzyme inhibitor. The prepared capsaicin film was characterized by “optical checking, smoothness color, transparency and flexibility, thickness of polymeric films, mass deviation, uniformity or texture, surface pH, tensile strength, cracking acceptance power, water ingestion amount, swelling ratio, wetness, and in-vitro drug release study”. Hydrophilic polymers chitosan increased water-soluble capsaicin spreadability and regulated drug release by 95.5% in 12 hours. The polymeric films (TLF6) were chosen for their look, tensile strength, percentage elongation, folding endurance, swelling ratio, moisture content, moisture uptake nature, drug content, and in-vitro drug release study parameters. Release kinetics showed that the produced film followed diffusion kinetics and released immediately. The release kinetic investigation showed that the patch followed super case II diffusion kinetics with sustained release over time. After regression analysis, slope values were calculated from the graph and r2 values indicated linearity.

Bioactive Based Nanotherapeutics

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Author : Rakesh K. Sindhu
language : en
Publisher: John Wiley & Sons
Release Date : 2025-07-29

Bioactive Based Nanotherapeutics written by Rakesh K. Sindhu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-29 with Technology & Engineering categories.

The book provides essential insights into the revolutionary potential of nanotechnology in medicine, exploring innovative approaches that harness natural materials for targeted and effective disease management. Nanotechnology has emerged as an innovative field with the potential to transform various sectors, including medicine and allied health sciences. Bioactive nanotherapeutics, a specific area within nanotherapeutics, utilizes natural materials or biomimetic designs to offer distinct advantages such as targeted drug delivery, biocompatibility, and improved therapeutic efficacy. These bioactive-based nanotherapeutics are used in the treatment and management of various diseases. Bioactive-Based Nanotherapeutics explores this rapidly growing field of therapeutics. It presents a broad overview of the fundamentals of bioactive nanomaterials, their design strategies, and their therapeutic applications. Leading experts from different disciplines have contributed chapters that explore a diverse range of topics, including the basics of bioactive nanotherapeutics, isolation methods of different bioactive compounds, and formulation developments. This volume addresses the importance of nanotechnology for the treatment and management of different diseases, including nasal, gastrointestinal, rectal, and transdermal diseases. Readers will find the book: Provides scientific research and evidence that supports the effectiveness of bioactive-based nanocarriers in treating diseases; Explores actionable steps and real-life scenarios to illustrate the practical benefits; Provides a comprehensive guide that explains the holistic approach, explaining health-related applications of bioactive-based nanoformulations. Audience Pharmacists, biologists, chemists, doctors, academics, and industry professionals interested in holistic and bioactive-based methods for disease treatment.

Handbook Of Encapsulation And Controlled Release

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Author : Munmaya Mishra
language : en
Publisher: CRC Press
Release Date : 2015-12-01

Handbook Of Encapsulation And Controlled Release written by Munmaya Mishra and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-01 with Medical categories.

The field of encapsulation, especially microencapsulation, is a rapidly growing area of research and product development. The Handbook of Encapsulation and Controlled Release covers the entire field, presenting the fundamental processes involved and exploring how to use those processes for different applications in industry. Written at a level comp

Handbook Of Nanotechnology In Nutraceuticals

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Author : Shakeel Ahmed
language : en
Publisher: CRC Press
Release Date : 2022-11-21

Handbook Of Nanotechnology In Nutraceuticals written by Shakeel Ahmed and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-21 with Technology & Engineering categories.

Nanotechnology has been emerging as an important tool in the nutraceutical and food industries to improve the overall quality of life. Nanotechnology has established a new horizon by bestowing modified properties on nanomaterials and applying them to the production of nanoformulations, nutritional supplements, and the food industry. The Handbook of Nanotechnology in Nutraceuticals highlights the impact of nanotechnology on the food industries. The book focuses on the application of nanotechnology in nutraceuticals and the food industry to improve the overall quality of life. The book also addresses some important applications of nano-nutraceuticals in the treatment of different diseases, such as oxidative stress, cancer, neurodegenerative disorders, cardiovascular diseases, and so on. Features • Presents a scientometric approach to analyze the emergence of nano-nutraceuticals in cancer prevention and treatment • Examines various strategies employed to prepare nanocarrier systems, such as nanoparticles, nanostructure lipids, phospholipid-based nanocarriers, polysaccharide-based nanostructures, and metal nanoparticles • Discusses various regulatory issues related to nanotechnology and their application in different fields This book is a valuable reference for nanotechnologists, scientists, and researchers working in the field of food technology, food science, pharmaceuticals, and nutraceuticals.

Advances In Novel Formulations For Drug Delivery

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Author : Raj K. Keservani
language : en
Publisher: John Wiley & Sons
Release Date : 2023-02-08

Advances In Novel Formulations For Drug Delivery written by Raj K. Keservani and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-08 with Science categories.

ADVANCES in NOVEL FORMULATIONS for DRUG DELIVERY The 27 chapters describe novel strategies for drug/nutraceutical delivery and embrace the development of formulations with herbal ingredients, while also highlighting disease therapeutics. Drug delivery technology has witnessed many advancements purported to cater to the customized needs of its ultimate beneficiaries—the patients. Today, dosage forms are not confined to conventional tablets, capsules, or injectables, but have evolved to cover novel drug carriers such as particulates, vesicles, and many others. Nanotechnological advancements have played a major role in this paradigm shift in ways of delivering active pharmaceutical ingredients. A new dimension in the use of food as medicine has also gained prominence in recent years. A portmanteau of nutrition and pharmaceuticals is “nutraceuticals,” also known as functional foods and dietary supplements. The technologies which were earlier included in drug delivery have been attempted for the delivery of nutraceuticals as well. Herbal actives have received increased attention due to their low risk-to-benefit ratio. The field of drug delivery is quite dynamic in nature, as witnessed by its evolution from conventional dosage forms to nanotechnology-assisted drug products. A variety of formulations via different drug delivery routes have been developed to treat/cure/mitigate diseases or disorders. This book, comprising of 27 chapters, is a thorough compilation of information relevant to drug delivery systems with an emphasis on products based on nanotechnology. Audience Researchers, scientists, industry professionals, formulators and product developers, regulatory agencies in a variety of settings including novel drug delivery research laboratories, pharmaceutical, and pharmacy industries, biomedical sciences, food and nutraceuticals manufacturers, and nanotechnology.

Nanophytomedicine

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Author : Sarwar Beg
language : en
Publisher: Springer Nature
Release Date : 2020-07-27

Nanophytomedicine written by Sarwar Beg and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-27 with Medical categories.

Nanophytomedicine is a field that involves the application of nanomedicine-based systems to phytotherapy and phytopharmacology. This book assesses the clinical successes and failures of nanophytomedicine and also highlights emerging concepts in this field. The content is divided into three sections, the first of which describes core issues in the pharmaceuticals industry in connection with the successes, failures and prospects of nanophytomedicine. The second section highlights recent advances in phytomedicine formulation development based on nanotechnology approaches, while also discussing a variety of nanocarrier systems for the successful delivery of phytomedicines. Focusing on the clinical perspective, the third section addresses the current clinical status of nanophytomedicine as a single drug therapy or combinatorial drug therapy, pharmacovigilance, pharmacokinetics, drug interactions and toxicological profiles, while also providing concluding remarks on recent experimental findings, and considering ethical issues & regulatory challenges in nanophytomedicine. Given its scope, the book offers a valuable guide for early career researchers, young scientists, master level students, academics and industrial scientists working in various healthcare fields, e.g. the pharmaceutical and biological sciences, life sciences, biotechnology, biomedical engineering, and nanobiotechnology.

Green Sustainable Process For Chemical And Environmental Engineering And Science

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Author : Jorddy Neves Cruz
language : en
Publisher: Elsevier
Release Date : 2023-03-23

Green Sustainable Process For Chemical And Environmental Engineering And Science written by Jorddy Neves Cruz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-23 with Technology & Engineering categories.

Green Sustainable Process for Chemical and Environmental Engineering and Science: Recent Advances in Nanocarriers covers nanocarrier synthesis techniques, as well as methods for encapsulating bioactive compounds. It explores the tests carried out to evaluate their pharmacological properties, in addition to investigating the recent results of clinical tests carried out for some nanocarriers. This book also addresses the most recent advances in nanocarriers and their diverse applications in modern medicine for the treatment of diseases and diagnostics. Nanocarriers play an important role in improving the treatment of diseases and diagnostic imaging as they can deliver medicines to specific locations for their actions and allow a prolonged release of the active compounds. This creates a need for researchers in academia and industry to obtain up-to-date knowledge about nanocarrier production and its pharmacological and biotechnological applications. This book contributes to this by providing the most recent and relevant topics on nanocarriers and by addressing pharmacological aspects for the treatment of various diseases, in addition to assessing the use for clinical diagnostics. So, it is a useful resource for students and researchers in the field of nanocarriers. - Discusses nanocarriers manufacture and nanoencapsulation process of molecules - Describes how nanocarriers reach the specific site of action and then release the drug - Explores the latest advances in different types of nanocarriers

Nanoagroceuticals Nanophytochemicals

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Author : Bhupinder Singh
language : en
Publisher: CRC Press
Release Date : 2018-11-19

Nanoagroceuticals Nanophytochemicals written by Bhupinder Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-19 with Science categories.

This book volume encompasses the recent trends made in the applications of nanoscale tools for diverse constituents of plants and agriculture, particularly in addressing the critical issues related to their safety, efficacy, and efficient and cost-efficient development and production.

Formulating Pharma Nutra And Cosmeceutical Products From Herbal Substances

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Author : Anupama Singh
language : en
Publisher: John Wiley & Sons
Release Date : 2025-07-31

Formulating Pharma Nutra And Cosmeceutical Products From Herbal Substances written by Anupama Singh and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-31 with Medical categories.

A practical and up-to-date discussion of the formulation and design of dosage forms and delivery systems containing herbal ingredients In Formulating Pharma-, Nutra-, and Cosmeceutical Products from Herbal Substances: Dosage Forms and Delivery Systems, a team of distinguished researchers delivers a step-by-step approach to preparing and manufacturing dosage forms and delivery systems. Intuitively organized with comprehensive coverage of the fundamentals, functional materials, manufacturing, and marketing of pharmaceutical, nutraceutical, and cosmeceutical products, the book also examines regulatory issues of quality, safety, and efficacy. The authors discuss essential formulation development and delivery information for novel and controlled delivery systems of herbal ingredients. Readers will also find: A thorough introduction to the basic principles of developing modern pharma-, nutra-, and cosmeceutical products from herbal substances Comprehensive explorations of conventional formulations, including issues of stability Practical discussions of advanced formulations, including chronotherapeutic delivery systems, liposome-based delivery of phytoconstituents, and nanoparticle mediated delivery of herbal actives Complete treatments of regulatory challenges, including nonclinical characterization and documentation for marketing authorizations of herbal formulations Perfect for professionals working in the herbal drug, natural product, and dietary supplement industries, Formulating Pharma-, Nutra-, and Cosmeceutical Products from Herbal Substances will also benefit academic researchers and graduate students studying herbal research, cosmetics, and pharmaceutical sciences.

Design And Applications Of Microneedles In Drug Delivery And Therapeutics

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Author : Prashant Kesharwani
language : en
Publisher: Elsevier
Release Date : 2024-06-28

Design And Applications Of Microneedles In Drug Delivery And Therapeutics written by Prashant Kesharwani and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-28 with Science categories.

Microneedles in Drug Delivery and Therapeutics details the design, characterization and applications of this novel drug delivery system.Microneedles offer several advantages over traditional oral and parenteral approaches, due to their ability to be fabricated and altered in shape, size and material type, matched to specific treatment needs.This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including: cancer therapy, gene and vaccine delivery, wound healing and more. Microneedles in Drug Delivery and Therapeutics is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery. - Introduces the reader to skin anatomy and materials development in regard to microneedles as smart carriers for drug delivery, offering an interdisciplinary approach that will appeal to a wide audience - Covers a broad range of therapeutic applications, from ocular diseases and photodynamic therapy to sensing and cancer treatment - Provides an overview of the materials, design, fabrication, clinical translation, commercial aspects of microneedle development, and their applications in drug delivery