Factors Influencing Isomer Discrimination By Modified Cyclodextrins
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Factors Influencing Isomer Discrimination By Modified Cyclodextrins
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Author : Darren Mark Schliebs
language : en
Publisher:
Release Date : 1999
Factors Influencing Isomer Discrimination By Modified Cyclodextrins written by Darren Mark Schliebs and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cyclodextrins categories.
Modified Cyclodextrins Scaffolds And Templates For Supramolecular Chemistry
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Author : Chris J Easton
language : en
Publisher: World Scientific
Release Date : 1999-04-29
Modified Cyclodextrins Scaffolds And Templates For Supramolecular Chemistry written by Chris J Easton and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-04-29 with Science categories.
Through modification, the natural cyclodextrins are effective templates for the generation of a wide range of molecular hosts. This makes it possible to tailor a cyclodextrin host to a particular guest, to meet specific requirements in the host-guest complex, and opens the way to diverse new areas of supramolecular chemistry. Metallocyclodextrins, rotaxanes and catenanes, as well as surface monolayers of modified cyclodextrins, are readily obtained. The native cyclodextrins serve as scaffolds on which functional groups and other substituents can be assembled, with controlled geometry. This results in substantially improved molecular recognition and procedures for chemical separation, including enantiomer discrimination, through guest binding. Access to the gamut of functional groups greatly expands the utility of cyclodextrins in chemical synthesis and provides catalysts which mimic the entire range of enzymic activity. Modifications to the cyclodextrins also lead to a wide range of photochemistry of cyclodextrin complexes, through which the enhancement of guest reactivity occurs; in addition, light harvesting molecular devices and photochemical frequency switches may be constructed. In solution, modified cyclodextrins have been used to construct molecular reactors, as well as molecular, temperature and pH sensors. At surfaces, they form semipermeable membranes and sensor electrodes. Such exciting fields of chemistry, made possible only through modifications to the natural cyclodextrins, are the subject of this book.
Chiral Separations By Capillary Electrophoresis
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Author : Ann Van Eeckhaut
language : en
Publisher: CRC Press
Release Date : 2009-11-11
Chiral Separations By Capillary Electrophoresis written by Ann Van Eeckhaut and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.
Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary ElectrophoresisSince the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist's toolkit. With contributions from international experts, Chiral Separations by
Capillary Electrophoresis In Chiral Analysis
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Author : Bezhan Chankvetadze
language : en
Publisher: John Wiley & Sons
Release Date : 1997-12-29
Capillary Electrophoresis In Chiral Analysis written by Bezhan Chankvetadze and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-12-29 with Science categories.
Das weltweite Interesse an der Trennung von Enantiomeren, Spiegelbildern ein und derselben chemischen Verbindung, nimmt zu, da diese Formen beispielsweise verschiedene physiologische Wirkungen hervorrufen können. Eine hochaktuelle Technik der Stofftrennung in diesem Zusammenhang ist die Kapillarelektrophorese, die hier von den theoretischen Grundlagen bis hin zu analytischen Details und Anbieterlisten ausführlich beschrieben wird.
Chirality In Drug Research
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Author : Eric Francotte
language : en
Publisher: John Wiley & Sons
Release Date : 2007-09-24
Chirality In Drug Research written by Eric Francotte and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-24 with Science categories.
Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data. In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions. With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1989
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.
Handbook Of Macrocyclic Supramolecular Assembly
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Author : Yu Liu
language : en
Publisher: Springer
Release Date : 2020-07-19
Handbook Of Macrocyclic Supramolecular Assembly written by Yu Liu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-19 with Science categories.
This handbook presents recent advances and offers a comprehensive reference resource covering the developments in and applications of macrocyclic supramolecular assembly, with a focus on their construction, structural characters and biological functions. The main topics addressed include: Construction and structure of macrocyclic supramolecular assembly – key building blocks, construction methods, structural motifs, and stimuli responsive control Approach and technology – controllable synthesis, molecular recognition, spectral and thermodynamic study, supramolecular assembly at interfaces, orthogonal self-assembly, the supramolecular organic framwork (SOF), molecular induced aggregation, supramolecule assisted 3D printing, theoretical calculation and molecular simulation Biological applications – chemical and biological sensing, theranostic tools, molecule/ion channels, drug/gene delivery, supramolecule assisted biomolecule production, supramolecule assisted transmembrane transport, supramolecule assisted immunity regulation, supramolecule-based medicinal drug, etc. This handbook appeals to graduate and undergraduate students as well as scientists with interests in supramolecular chemistry, biochemistry, functional material and nanotechnology.
Chiral Liquid Chromatography
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Author : w Lough
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chiral Liquid Chromatography written by w Lough and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
While working as a chromatographer in the pharmaceutical industry, it became apparent to the editor that there was a pressing need for a comprehensive reference text for analysts working on the resolution of enantiomers by liquid chromatography (LC). This need arises from the fact that, whereas previously it was very difficult to determine enantiomers by direct means, there is now a wide choice of direct LC methods. At the same time, regulatory authorities have been changing their attitudes towards the administration of pharmaceuticals as racemates, partly because it is now possible to study the individual enantiomers. Clearly this abundance of new information needs to be rationalized. More importantly, the chiral LC systems which are commercially available or readily accessible to the practising chromatographer needed to be reviewed and, to a much greater extent than in existing reviews or books, discussed in terms of their practical application. Accordingly this book is very much orientated towards the practical aspects of these commercially available and readily accessible chiral LC systems. To this end, it is written for practising chromatographers by a team of practising, experienced chromatographers who have spent many years tackling the problems presented by resolving enantiomers by LC. The practical aspects of common chiral LC systems cannot be fully understood if discussed in isolation.
Physics Briefs
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Author :
language : en
Publisher:
Release Date : 1988
Physics Briefs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Physics categories.
European Pharmacopoeia
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Author : Council of Europe
language : en
Publisher:
Release Date : 2010
European Pharmacopoeia written by Council of Europe and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Drugs categories.
The 7th edition of the European Pharmacopoeia was published July 15 2010 and consists of a two-volume main edition. It is complemented by non-cumulative supplements that are to be kept for the duration of the 7th Edition. Two supplements were published in 2010 and three supplements will be published in each 2011 and 2012. It contains information on all types of active substances used to prepare pharmaceutical products: various chemical substances, antibiotics, biological substances, vaccines for human or veterinary use, immunosera, radiopharmaceutical preparations, herbal drugs and homoepathic preparations. Over 1800 specific and general monographs are included.