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Familial Polyposis Coli And Colorectal Cancer


Familial Polyposis Coli And Colorectal Cancer
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Familial Polyposis Coli And Colorectal Cancer


Familial Polyposis Coli And Colorectal Cancer
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Author : Susan Helen Rider
language : en
Publisher:
Release Date : 1986

Familial Polyposis Coli And Colorectal Cancer written by Susan Helen Rider and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Colon (Anatomy) categories.




Familial Adenomatous Polyposis


Familial Adenomatous Polyposis
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Author : Lemuel Herrera
language : en
Publisher: Wiley-Liss
Release Date : 1990

Familial Adenomatous Polyposis written by Lemuel Herrera and has been published by Wiley-Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.


A comprehensive assessment of basic research and clinical management of FAP, including guidelines for diagnosis, screening, and treatment. Covers differential diagnosis, physical examination, clinical markers, tests, pre- and post-surgical management, and follow-up strategies.



Familial Polyposis Coli


Familial Polyposis Coli
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Author : H. J. R. Bussey
language : en
Publisher:
Release Date : 1975

Familial Polyposis Coli written by H. J. R. Bussey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with History categories.




Hereditary Colorectal Cancer


Hereditary Colorectal Cancer
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Author : Miguel A. Rodriguez-Bigas
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-10

Hereditary Colorectal Cancer written by Miguel A. Rodriguez-Bigas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-10 with Medical categories.


Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.



Hereditary Colorectal Cancer


Hereditary Colorectal Cancer
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Author : Joji Utsunomiya
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-27

Hereditary Colorectal Cancer written by Joji Utsunomiya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Medical categories.


Since the success in chemical induction of cancer in rabbit's ear skin by K. Yamagiwa in 1915, oncologists of the world have come to believe that they can only solve their problems by means of animal experimen tation. The importance of environmental factors became moreevident in 1935 when T. Yoshida and T. Sasaki introduced azodye hepatocarcino genesis in rats. In the domain of the gastrointestinal tract, T. Sugimura has more recently accumulated enough evidence to indicate that locally active chemical mutagens are carcinogenic. In contrast, principal approaches to colorectal tumors have been quite different: emphasis has been placed on gene identification. Long before cancer of the large bowel was recognized, importance of the roles of adenomatosis coli and its familial occurrence attracted the attention of epidemiologists and geneticists. Morphological characteri zation and analysis of hereditary trends of human material have already bad a long history, and recently detailed analysis of genetic material has become feasible in the wake of rapid development in our knowledge of the oncoviruses, oncogenes, suppressor genes, chromosomal and DNA mapping, molecular mutation and so on. lt is true that in colorectal pathology, and in no other field, these areas of research have been explored more extensively and decisively. The identification of previ ously ill-defined lesions such as precancers and benign neoplasms have been improved because sequential changes can be observed in multiple samples spread over a wide area and followed up in due course.



Genetics Of Colorectal Cancer For Clinical Practice


Genetics Of Colorectal Cancer For Clinical Practice
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Author : Fred H. Menko
language : en
Publisher: Springer Science & Business Media
Release Date : 1993-07-31

Genetics Of Colorectal Cancer For Clinical Practice written by Fred H. Menko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07-31 with Medical categories.


Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic predisposition. Those directly involved in the treatment of patients with cancer of the large bowel are confronted to an increasing degree with the genetic aspects of the disease. In familial and hereditary forms of the disorder periodic screening of the close relatives of the patients can in principle prevent disease and death from colorectal cancer. Presymptomatic diagnosis by means of DNA technology is now possible in many cases of familial adenomatous polyposis. Genetic diagnosis will be increasingly important for the identification of high-risk groups. This book summarizes those aspects of the genetics of colorectal cancer that are important for clinical pracice. It has been stated that clinicians can contribute to the goal of reducing mortality from cancer by asking each patient about his or her family history of cancer. The aim of this book is to provide a guideline for the management of those situations in which the family history of colorectal cancer is found to be positive.



Adenomatous Polyps Of The Colon


Adenomatous Polyps Of The Colon
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Author : Robert Lev
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-27

Adenomatous Polyps Of The Colon written by Robert Lev and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-27 with Medical categories.


Adenomatous Polyps of the Colon: Pathobiological and Clinical Features consolidates the vast body of basic science and clinical data associated with adenomatous polyps of the colon, much of it inspired by the realization that most colorectal carcinomas seem to arise in such polyps. This book strives to evaluate these data, with particular emphasis on their implications for management of polyp-bearing subjects. Topics comprehensively explored include anatomy and histology of the normal colon; pathologic characteristics of adenomatous polyps, differential diagnosis, and grading schemes for degree of dysplasia and villosity; adenomatous polyposes; histologic and epidemiologic evidence for the malignant potential of adenomatous polyps; and detection and management, with special attention to endoscopy, endoscopic polypectomy, the malignant polyp, and post-polypectomy surveillance schedules.



Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2012 Edition


Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-10

Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-10 with Medical categories.


Adenomatous Polyposis Coli: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adenomatous Polyposis Coli in a compact format. The editors have built Adenomatous Polyposis Coli: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adenomatous Polyposis Coli in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adenomatous Polyposis Coli: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Association Of Missense Polymorphisms In The Adenomatous Polyposis Coli Gene And Colorectal Cancer Microform


Association Of Missense Polymorphisms In The Adenomatous Polyposis Coli Gene And Colorectal Cancer Microform
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Author : Sean P. (Sean Patrick) Cleary
language : en
Publisher: National Library of Canada = Bibliothèque nationale du Canada
Release Date : 2004

Association Of Missense Polymorphisms In The Adenomatous Polyposis Coli Gene And Colorectal Cancer Microform written by Sean P. (Sean Patrick) Cleary and has been published by National Library of Canada = Bibliothèque nationale du Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.


Background. 20% of Colorectal cancer (CRC) patients have a family history of the disease. It has been proposed that missense polymorphisms in the Adenomatous polyposis coli (APC) may contribute to CRC risk. Results. In 39 multiple-polyp CRC patients we identified 3 novel and 2 previously described APC variants. A novel truncating mutation (Y94X) was observed in a single CRC patient with multiple adenomatous polyps. The S 130G (0.3% vs 0.1%, p = 0.625); E1317Q (1.8% vs 1.9%, p = 0.823); and G2502S (4.6% vs 4.9%, p = 0.625) polymorphisms were observed in similar frequencies among CRC cases and controls. The D1822V carriers (homozygous or heterozygous) were less common in CRC cases than in controls (37.6% vs 42.6%, p = 0.029). Methods. To identify missense polymorphisms in the APC gene, we sequenced the entire open-reading frame of APC in 39 CRC patients with>5 synchronous adenomatous polyps. We then determined the frequency of these polymorphisms in 971 CRC patients and 954 healthy population controls.



Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2011 Edition


Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09

Adenomatous Polyposis Coli New Insights For The Healthcare Professional 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.


Adenomatous Polyposis Coli: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Adenomatous Polyposis Coli in a compact format. The editors have built Adenomatous Polyposis Coli: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adenomatous Polyposis Coli in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adenomatous Polyposis Coli: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.