Genetics Of Colorectal Cancer For Clinical Practice
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Genetics Of Colorectal Cancer For Clinical Practice
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Author : Fred H. Menko
language : en
Publisher: Springer Science & Business Media
Release Date : 1993-07-31
Genetics Of Colorectal Cancer For Clinical Practice written by Fred H. Menko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07-31 with Medical categories.
Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic predisposition. Those directly involved in the treatment of patients with cancer of the large bowel are confronted to an increasing degree with the genetic aspects of the disease. In familial and hereditary forms of the disorder periodic screening of the close relatives of the patients can in principle prevent disease and death from colorectal cancer. Presymptomatic diagnosis by means of DNA technology is now possible in many cases of familial adenomatous polyposis. Genetic diagnosis will be increasingly important for the identification of high-risk groups. This book summarizes those aspects of the genetics of colorectal cancer that are important for clinical pracice. It has been stated that clinicians can contribute to the goal of reducing mortality from cancer by asking each patient about his or her family history of cancer. The aim of this book is to provide a guideline for the management of those situations in which the family history of colorectal cancer is found to be positive.
Colorectal Cancer In Clinical Practice
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Author : Bernard Levin
language : en
Publisher: CRC Press
Release Date : 2005-11-23
Colorectal Cancer In Clinical Practice written by Bernard Levin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-23 with Medical categories.
The rapid rate of development in the fields of prevention, early detection and management for colorectal cancer means that the successful first edition of this accessible guide has needed to be updated and revised throughout. Primary care physicians and specialists alike will continue to find this an indispensable synopsis of the issues and options.
Lynch Syndrome
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Author : Naohiro Tomita
language : en
Publisher: Springer Nature
Release Date : 2020-08-24
Lynch Syndrome written by Naohiro Tomita and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with Medical categories.
This book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition. Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease’s manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome. Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.
Colorectal Cancer In Clinical Practice
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Author : Bernard Levin
language : en
Publisher: CRC Press
Release Date : 2001-12-20
Colorectal Cancer In Clinical Practice written by Bernard Levin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-12-20 with Medical categories.
Colorectal cancer is one of the major malignancies affecting westernized societies, both in terms of incidence and as a cause of mortality: it is, however, a preventable and a detectable disease. Although most countries do not actively promote preventive policies for their general population, this trend is gradually changing. In line with this current development, Colorectal Cancer in Clinical Practice examines prevention and early detection of this disease, as well as discussion of management issues. It will provide the clinician with an accessible and up-to-date guide on the primary and secondary prevention of colorectal cancer, and will be of particular interest to primary care physicians and specialists in gastroenterology, oncology and surgery.
A Guide To Cancer Genetics In Clinical Practice
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Author : Sue Clark,
language : en
Publisher: tfm Publishing Limited
Release Date : 2009-05-01
A Guide To Cancer Genetics In Clinical Practice written by Sue Clark, and has been published by tfm Publishing Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-01 with Medical categories.
FIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions.
Genetics Of Colorectal Cancer
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Author : John D. Potter
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-07
Genetics Of Colorectal Cancer written by John D. Potter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-07 with Medical categories.
Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Hereditary Colorectal Cancer
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Author : Miguel A. Rodriguez-Bigas
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-10
Hereditary Colorectal Cancer written by Miguel A. Rodriguez-Bigas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-10 with Medical categories.
Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.
Cancer Principles And Practice Of Oncology Handbook Of Clinical Cancer Genetics
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Author : Ellen Matloff
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2013-03-25
Cancer Principles And Practice Of Oncology Handbook Of Clinical Cancer Genetics written by Ellen Matloff and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-25 with Medical categories.
This practical, user-friendly guidebook will allow the clinician to search under disease site for the hereditary cancer syndromes relevant for his/her patient's cancer. For example, a gynecologist oncologist whose patient has ovarian cancer can turn to the Ovary chapter and quickly read a summary of all of the hereditary cancer syndromes that include ovarian cancer. She can learn the questions she should be asking when expanding that patient's personal and family history, which genes are most relevant, whether to refer that patient on for genetic counseling and testing, and how to manage that patient long-term if the patient is mutation positive or negative. The same holds true for the practicing oncologist, surgeon, urologist, endocrinologist, gynecologist, primary care physician, physician's assistant, advanced practice nurse and any other clinician seeing a patient who has had cancer. This guidebook also contains an overview article on genetic counseling and testing and several in depth articles on issues that are up and coming in the field of hereditary cancer.
Cancer Family
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Author : C. Richard Boland, MD
language : en
Publisher: AuthorHouse
Release Date : 2015-08-30
Cancer Family written by C. Richard Boland, MD and has been published by AuthorHouse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-30 with Biography & Autobiography categories.
It is 1946, and a young man stares out his third-story apartment window. He has returned from the war with metastatic cancer and assumes he will die, leaving his wife and infant daughter behind. Instead, he lives another twenty-four years, raising a family of four children, before he succumbs to a second colon cancer. His son, the author, recognizes that there is a hereditary cancer syndrome in the family and resolves to solve the problem as a medical researcher. Eventually, hereditary colorectal cancer is recognized as a medical entity, and multiple genes responsible for this hereditary condition are isolated. However, the mutation responsible in the author’s family escaped detection. In 2001, his laboratory identifies the mutation responsible for the problem and develops a specific test for the family. This permits the mutation carriers to obtain life-saving care, altering the natural history of the disease for his family and others.
The Value Of Genetic And Genomic Technologies
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-12-29
The Value Of Genetic And Genomic Technologies written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-29 with Medical categories.
Knowing one's genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOM's Roundtable on Translating Genomic-Based Research for Health held a workshop on March 22, 2010, to bring together diverse perspectives on the value of genetic testing, and to discuss its use in clinical practice.