Fast Facts Molecular Profiling In Solid Tumors
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Fast Facts Molecular Profiling In Solid Tumors
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Author : Parneet Cheema
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2022-11-14
Fast Facts Molecular Profiling In Solid Tumors written by Parneet Cheema and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-14 with Medical categories.
Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities
Fast Facts Molecular Profiling In Solid Tumors
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Author : Parneet Cheema
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2022-12-06
Fast Facts Molecular Profiling In Solid Tumors written by Parneet Cheema and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Medical categories.
Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results.
Fast Facts Cholangiocarcinoma
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Author : Rachna T. Shroff
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2021-04-08
Fast Facts Cholangiocarcinoma written by Rachna T. Shroff and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-08 with Medical categories.
Cholangiocarcinomas (CCAs) are a group of heterogeneous tumors that have traditionally had poor prognosis. Despite being rare, the global incidence of CCA has increased dramatically over the last few decades. However, alongside this, there have been advancements in our understanding, diagnosis and treatment, improving the overall survival and quality of life of patients with advanced disease. This compact yet comprehensive review of CCA serves as a guide for physicians, oncologists, allied health professionals, scientists, patients and caregivers to update their knowledge of the most recent clinical developments and most promising areas of research.
Diagnostic Pathology Molecular Oncology E Book
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Author : Mohammad A. Vasef
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-12-04
Diagnostic Pathology Molecular Oncology E Book written by Mohammad A. Vasef and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-04 with Medical categories.
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Providing a clear understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer in an era of personalized medicine, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Molecular Oncology is a visually stunning, one-stop resource for every practicing pathologist, hematopathologist, molecular pathologist, oncologist, or pathologist in training as an ideal day-to-day reference or as a reliable learning resource. - Provides up-to-date, comprehensive coverage of relevant molecular tests and their clinical applications, along with organ-based chapters on the molecular genetic data relevant to individual disease entities - Contains new chapters and substantial revisions to existing content that include updates from the 2022 International Consensus Classification and the WHO Classification of Haematolymphoid Tumours, fifth edition - Provides expert guidance on selecting the right test(s) at the right time, as well as comparisons of molecular testing methods (e.g., FISH vs. cytogenetics) - Includes current information for new actionable mutations and targeted therapies - Covers ultrasensitive molecular techniques for minimal residual disease detection and disease monitoring - Discusses circulating cell-free DNA analysis for detection of resistance-associated mutations and disease monitoring, and provides usage details - Features an image-rich layout with more than 2,400 print and online-only images, including high-resolution H&E stains, immunostains, FISH images, gross pathology and clinical photographs, detailed full-color medical illustrations, and informative diagrams, charts, and schematics - Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care - Any additional digital ancillary content may publish up to 6 weeks following the publication date
Challenges Updates In Pediatric Pathology An Issue Of Surgical Pathology Clinics E Book
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Author : Jessica L. Davis
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-11-19
Challenges Updates In Pediatric Pathology An Issue Of Surgical Pathology Clinics E Book written by Jessica L. Davis and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Medical categories.
This issue of Surgical Pathology Clinics, guest edited by Dr. Jessica Davis, is devoted to Challenges & Updates in Pediatric Pathology. Articles in this issue include: Advances and Pitfalls in the Diagnosis of Hirschsprungs Disease, Updates in Pediatric Enteropathies: Differential Diagnosis, Testing, and Genetics, Pediatric Liver Tumors: Updates in Classification, New Prognostic Indicators in Pediatric Adrenal Tumors: Neuroblastoma & Adrenal Cortical Tumors, Pediatric Cystic Lung Lesions, Strategies for the Neonatal Lung Biopsy: Histology to Genetics, Wilm's Tumor: Challenges and Newcomers in Prognosis, Pediatric Renal Tumors: Updates in the Molecular Era, Newcomers in Vascular Anomalies, Spindle Cell Rhabdomyosarcoma: Further Subcategorization, Pediatric & Infantile Fibroblastic/myofibroblastic Tumors in the Molecular Era, Round Cell Sarcomas: Newcomers and Diagnostic Approaches, CNS Embryonal Tumors: Testing Strategies for Integrated Diagnosis, Updates in Pediatric Gliomas, and more.
Diagnostic Pathology Breast E Book
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Author : Susan C. Lester
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-02-19
Diagnostic Pathology Breast E Book written by Susan C. Lester and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-19 with Medical categories.
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of breast pathology, it incorporates the most recent clinical, pathological, radiological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Breast is a one-stop reference for accurate, complete surgical pathology evaluation—ideal as a day-to-day reference or as a reliable training resource. - Includes a wide range of new information on breast pathology, including material specific to core needle biopsies, to help you identify, diagnose, and manage disease - Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays - Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer - Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds - Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality - Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations - Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference - Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Diagnostic Pathology Breast Ebook
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Author : Susan C. Lester
language : en
Publisher: Elsevier Health Sciences
Release Date : 2025-05-06
Diagnostic Pathology Breast Ebook written by Susan C. Lester and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-06 with Medical categories.
This expert volume in the Diagnostic Pathology series is not only an up-to-date, comprehensive diagnostic support tool for surgical pathologists, but also a valuable resource for all health care workers who provide care to patients with breast disease, including radiologists as well as surgical, medical, and radiation oncologists. An excellent point-of-care reference for practitioners at all levels of experience and training, the fourth edition of Diagnostic Pathology: Breast, Fourth Edition provides details on normal breast histology, information to assist in processing breast specimens, and multichapter sections on diagnostic patterns, benign lesions, carcinomas, predictive and prognostic factors, stromal lesions, inflammatory lesions, lymphomas, and hereditary breast disease. Richly illustrated and easy to use, this volume is ideal as a one-stop resource for day-to-day reference or as a reliable training resource. - Incorporates the most up-to-date scientific and technical knowledge, providing a comprehensive overview of all key issues relevant to today's practice - Emphasizes the correlation of pathologic lesions with findings on breast imaging and provides guidance on the interpretation of core needle biopsies - Contains new overview chapters that lay the groundwork for initial evaluation and assistance with differential diagnosis, as well as new chapters on HER2-low breast carcinoma, immunohistochemical studies for diagnosis, proliferation, and more - Provides important updates throughout, covering the evaluation of ESR1, PIK3CA, AKT, and BRCA1 mutations to guide therapy; tumor-infiltrating lymphocytes and PD-L1 for treatment planning; HER2-low assessment to determine eligibility for antibody-drug conjugates; and much more - Features new animations and new videos to assist in understanding three-dimensional anatomy, radiologic-pathologic correlation, the processing of breast specimens, and the gross identification of breast lesions - Contains more than 3,700 extensively annotated images, including gross pathology photographs, histopathology photomicrographs, a wide range of immunohistochemical stains, fluorescent in situ hybridization, breast-imaging studies, and full-color illustrations - Employs consistently templated chapters, bulleted content, key facts, annotated images, and an extensive index for quick, expert reference at the point of care
Diagnostic Imaging Brain E Book
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Author : Miral D. Jhaveri
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-11-20
Diagnostic Imaging Brain E Book written by Miral D. Jhaveri and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-20 with Medical categories.
Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Brain, fourth edition, is an invaluable resource for neuroradiologists, general radiologists, and trainees—anyone who requires an easily accessible, highly visual reference on today's neuroimaging of both common and rare conditions. World-renowned authorities provide updated information on more than 300 diagnoses, all lavishly illustrated, delineated, and referenced, making this edition a useful learning tool as well as a handy reference for daily practice. - Provides authoritative, comprehensive guidance on both pathology-based and anatomy-based diagnoses to help you diagnose the full range of brain and CNS conditions - Features thousands of extensively annotated images, including a large number of full-color illustrations—greatly expanded since the previous edition - Details 31 new diagnoses, covering key topics such as critical illness-associated microbleeds, autoimmune encephalitis, multinodular and vacuolating tumor of cerebrum, calcifying pseudoneoplasm of neuraxis (CAPNON), uremic encephalopathy, gadolinium deposition and associated controversies, ataxia-telangiectasia, and Zika virus infection - Reflects updates from the most recent WHO Classification of Tumors of the CNS, which presents major restructuring of brain tumor categories and incorporates new entities that are defined by both histology and molecular features - Includes updates to the 2016 WHO Classification of Tumors of the CNS by cIMPACT-NOW based on recent and ongoing advances in molecular pathogenesis - Covers recent neuroimaging advances, such as 7T MRI scanners and dual-energy/dual-source CT imaging - Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care
Diagnostic Pathology Endocrine E Book
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Author : Vania Nosé
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-08-27
Diagnostic Pathology Endocrine E Book written by Vania Nosé and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-27 with Medical categories.
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. - Provides essential knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, paraganglia, pancreas, skin, neuroendocrine neoplasms, and inherited tumor syndromes—more than 150 diagnoses in all - Offers a wealth of new information based on recently recognized and discovered endocrine diseases, as well as tumor types with important implications for patient care - Includes new content on thyroid lesions and tumors now associated with DICER1 gene mutations; the correlation of newly characterized genetic abnormalities in endocrine tumors associated with responses to targeted therapies; and newly recognized syndromes, such as multiple endocrine neoplasia type 4 and type 5, glucagon cell hyperplasia and neoplasia, and others - Meticulously edited by Dr. Vania Nosé with contributions from renowned pathologists to ensure that common/classic endocrine diagnoses as well as newly recognized diseases and unusual cases, are well covered - Features nearly 2,200 high-quality images in print and online, including clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis - Includes updated criteria, terminology, and classifications for a wide range of tumors according to the latest literature, including the 2022 WHO Endocrine and Neuroendocrine Tumors classification - Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care - Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Diagnostic Pathology Breast
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Author : Susan C. Lester, MD, PhD
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-02-10
Diagnostic Pathology Breast written by Susan C. Lester, MD, PhD and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-10 with Medical categories.
Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Breast, second edition, is a visually stunning, easy-to-use reference covering all aspects of breast pathology. Outstanding images, including gross and microscopic pathology, a wide range of supportive immunohistochemistry, and detailed medical illustrations with numerous examples of morphologic findings, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Thoroughly updated content throughout, including coverage of new technologies and molecular approaches that are quickly moving out of the laboratory into clinical diagnosis and therapeutic decision making New to this edition: Tips on how to biopsy and send the best block for breast cancer predictive factor testing, updated prognostic assays, updated national guidelines (including HER2 testing) with photos, neoadjuvant treatment, new drugs for HER2-positive cancers, and pattern-based differential diagnosis chapters and guidance on the most helpful IHC antibodies For each anatomical site, you will find CAP cancer staging and specimen handling protocols, plus detailed immunohistochemistry panels to accompany the images High-quality, carefully annotated color images provide clinically and diagnostically important information Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while new images and outstanding graphics make this text ideal for both residents and practitioners Time-saving reference features include bulleted text, a variety of data tables, key facts in each chapter, annotated images, and an extensive index Expert Consult eBook version included, which allows you to search all of the text, figures, and references from the book on a variety of devices