Fate And Effects Of Anticancer Drugs In The Environment
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Fate And Effects Of Anticancer Drugs In The Environment
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Author : Ester Heath
language : en
Publisher: Springer Nature
Release Date : 2020-01-01
Fate And Effects Of Anticancer Drugs In The Environment written by Ester Heath and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-01 with Science categories.
The book provides current knowledge and research on the presence and effects of anticancer drug residues in the aqueous environment and covers all relevant aspects of the presence of these residues in wastewaters and natural aquatic systems, where numerous analogies between their pharmacokinetics and pharmacodynamics in humans and their effects in the environment can be drawn. This book comprises of 18 chapters and represents the combined work of leading scientists from different research institutions from across the globe. We present the state of the art in the field of anticancer drug residues in the aquatic environment while being cognizant of the many challenges that remain.
Emerging Contaminants In The Environment
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Author : Hemen Sarma
language : en
Publisher: Elsevier
Release Date : 2022-01-08
Emerging Contaminants In The Environment written by Hemen Sarma and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-08 with Science categories.
Emerging Contaminants in the Environment: Challenges and Sustainable Practices covers all aspects of emerging contaminants in the environment, from basic understanding to different types of emerging contaminants and how these threaten organisms, their environmental fate studies, detection methods, and sustainable practices of dealing with contaminants. Emerging contaminant remediation is a pressing need due to the ever-increasing pollution in the environment, and it has gained a lot of scientific and public attention due to its high effectiveness and sustainability. The discussions in the book on the bioremediation of these contaminants are covered from the perspective of proven technologies and practices through case studies and real-world data. One of the main benefits of this book is that it summarizes future challenges and sustainable solutions. It can, therefore, become an effective guide to the elimination (through sustainable practices) of emerging contaminants. At the back of these explorations on sustainable bioremediation of emerging contaminants lies the set of 17 goals articulated by the United Nations in its 2030 Agenda for Sustainable Development, adopted by all its member states. This book provides academics, researchers, students, and practitioners interested in the detection and elimination of emerging contaminants from the environment, with the latest advances by leading experts in emerging contaminants the field of environmental sciences. Covers most aspects of the most predominant emerging contaminants in the environment, including in soil, air, and water Describes the occurrence of these contaminants, the problems they cause, and the sustainable practices to deal with the contaminants Includes data from case studies to provide real-world examples of sustainable practices and emerging contaminant remediation
Pharmaceutical Residues In Freshwater Hazards And Policy Responses
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Author : Organisation for Economic Co-Operation and Development (OECD)
language : en
Publisher: IWA Publishing
Release Date : 2020-07-15
Pharmaceutical Residues In Freshwater Hazards And Policy Responses written by Organisation for Economic Co-Operation and Development (OECD) and has been published by IWA Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-15 with Science categories.
This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life‑cycle approach to managing pharmaceuticals in the environment. A policy mix of source‑directed, use‑orientated and end‑of‑pipe measures, involving several policy sectors, can help to improve health and protect the environment.
Handbook Of Anticancer Drugs From Marine Origin
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Author : Se-Kwon Kim
language : en
Publisher: Springer
Release Date : 2014-11-27
Handbook Of Anticancer Drugs From Marine Origin written by Se-Kwon Kim and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-27 with Science categories.
This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 427 Skin Absorption In Vivo Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2004-11-23
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 427 Skin Absorption In Vivo Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-23 with categories.
The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline ...
Medicinal Chemistry Of Chemotherapeutic Agents
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Author : Pratap Chandra Acharya
language : en
Publisher: Academic Press
Release Date : 2023-03-09
Medicinal Chemistry Of Chemotherapeutic Agents written by Pratap Chandra Acharya and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-09 with Medical categories.
Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure–activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any. This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents. Includes current research focused on drug resistance and methods to overcome problems Outlines synthetic schemes and metabolic pathways of chemotherapeutic agents Discusses molecules under clinical trials and newly approved drugs
Medicinal Chemistry Of Anticancer Drugs
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Author : Carmen Avendaño
language : en
Publisher: Elsevier
Release Date : 2015-06-11
Medicinal Chemistry Of Anticancer Drugs written by Carmen Avendaño and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-11 with Science categories.
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature
Emerging Anti Aging Strategies
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Author : Syed Ibrahim Rizvi
language : en
Publisher: Springer Nature
Release Date : 2023-01-30
Emerging Anti Aging Strategies written by Syed Ibrahim Rizvi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-30 with Science categories.
The book focuses on the emerging anti-aging approaches for maintaining better health in old age. It provides a current understanding of the underlying principle, possible targets, implementation approaches, and efficacy of the various anti-aging strategies. The chapters include a wide range of topics incorporating the major advances in anti-aging strategies, including telomerase activation, stem cell therapy, autophagy induction, sirtuin activation, and dietary restrictions. Further, it discusses the epigenetic mechanisms underlying aging-related processes and epigenetic strategies to delay and reverse aging-related diseases. The book covers the strategy based on tissue engineering and regenerative medicine for understanding the complexity of aging and restoring the functionalities of organ systems. It further presents the applications of melatonin supplementation-based anti-aging therapeutic intervention. Finally, the book reviews the ethical dimension of anti-aging intervention strategies. This book is immensely useful to scientists and researchers from various disciplines in the life sciences.
Management Of Contaminants Of Emerging Concern Cec In Environment
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Author : Pardeep Singh
language : en
Publisher: Elsevier
Release Date : 2021-03-12
Management Of Contaminants Of Emerging Concern Cec In Environment written by Pardeep Singh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-12 with Technology & Engineering categories.
Management of Contaminants of Emerging Concern (CEC) in Environment provides information about new concepts and latest developments in origin, reaction pathways, transportation, transformation products, identification, and adverse effects of CEC, as well as recent remediation technologies and tools for CEC. The book explores processes such as nanotechnology for the degradation of CEC by using various heterogeneous catalysts. The chapters incorporate both theoretical and practical aspects and can serve as a baseline for future studies. So, Management of Contaminants of Emerging Concern (CEC) in Environment is an indispensable resource for university students, teachers, and researchers, especially those working in the area of remediation and management of contaminants of emerging concern. Takes a holistic approach, focusing on the origin of contaminants, type of contaminants, remediation technologies, regulations and legal aspects Applies chemical, physical and biological processes for the treatment of emerging contaminants Written by a team of internationally reputed and rising researchers
Hospital Wastewaters
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Author : Paola Verlicchi
language : en
Publisher: Springer
Release Date : 2017-09-04
Hospital Wastewaters written by Paola Verlicchi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-04 with Technology & Engineering categories.
This volume addresses hospital effluents in terms of their composition and the management and treatment strategies currently (being) adopted around the globe. In this context, one major focus is on pharmaceutical compounds: their observed concentration range, ecotoxicological effects, and the removal efficiency achieved by the different technologies. Another focus is on management strategies (dedicated hospital wastewater treatment, or a combined approach also involving urban wastewater) and currently adopted treatments to reduce the released pollutant load. Innovative and promising technologies under investigation at the lab and pilot scale are presented. A discussion of remaining knowledge gaps and future research requirements rounds out the coverage. The respective chapters, written by experts in the different fields, provide useful information for a broad audience: scientists involved in the management and treatment of hospital effluents and wastewater containing micropollutants, administrators and decision-makers, legislators involved in the authorization and management of healthcare structure effluents, and environmental engineers involved in the design of wastewater treatment plants, as well as newcomers and students interested in these issues.