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Fibrosis And Inflammation In Tissue Pathophysiology


Fibrosis And Inflammation In Tissue Pathophysiology
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Fibrosis And Inflammation In Tissue Pathophysiology


Fibrosis And Inflammation In Tissue Pathophysiology
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Author : Elvira Forte
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-23

Fibrosis And Inflammation In Tissue Pathophysiology written by Elvira Forte and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-23 with Science categories.




Tissue Repair And Fibrosis


Tissue Repair And Fibrosis
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Author : Alexis Desmouliere
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Tissue Repair And Fibrosis written by Alexis Desmouliere and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


With contributions by numerous experts



Fibrosis In Disease


Fibrosis In Disease
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Author : Monte S. Willis
language : en
Publisher: Springer
Release Date : 2018-11-10

Fibrosis In Disease written by Monte S. Willis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-10 with Medical categories.


Fibroproliferative diseases are a broad spectrum of entities from organ-specific involvement (e.g., pulmonary, heart, liver, and kidney fibrosis) to multi-system diseases such as systemic sclerosis and sclerodermatous graft vs. host disease. These diseases also encompass pathophysiologies not readily recognizably related, such as macular degeneration and cancer metastasis. Fibroproliferative diseases are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Remarkable progress in elucidating the pathogenesis of these common diseases with fibrotic components, including the critical roles of myofibroblasts and the molecular mechanisms driving the transcriptional activation involved in the induction of fibrosis. As the importance of these processes is realized in the long-term recovery and treatment of diseases, effective anti-fibrotic therapies targeting the underlying ongoing disease processes are lacking. The complexity of discovering and applying therapies to fibroproliferative disease may be due to the diversity of the systems the pathogenesis of disease itself involves. By nature, fibroproliferative diseases are interdisciplinary, involving multiple cell types (organ-specific epithelial cells), immune cells, endothelial cells, and fibroblasts. Bone marrow, cytokines, and organ-specific pathologies further speckle both the clinical and scientific disciplines in such a way that communication is often limited to the clinical or scientific tribes we live in, despite the greatest access to information known to man available today. Therefore, the primary focus of this text is to bring together authors from a diversity of both clinical, scientific, and therapeutic backgrounds for readers to more fully appreciate that fantastic platform that is available to build upon to lessen the isolation of the clinical and scientific disciplines. With advances in the discovery of pre-clinical therapeutic targets (at least 20+ to date) involving TGF-beta (and other cytokines), transcription factors, and downstream kinases, it’s important to both recognize the broader impact and potential opportunities that exist even today. This book will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of fibroproliferative diseases. The book will provide new insight into the fundamental mechanisms of classic fibrotic pathophysiologic processes like myocardial infarction, idiopathic pulmonary fibrosis, chronic kidney disease, wound healing, and systemic sclerosis. It will also highlight the many new areas of therapeutic investigation currently underway. Lastly, we will touch upon newly emerging fields investigating the role of fibrosis in macular degeneration and cancer metastasis. The chapters will be written by established experts in their fields, including clinicians (cardiologists, cardiovascular surgeons, pathologists, and general practitioners) and translational biomedical researchers in a wide range of disciplines. However, the material will certainly have a broader audience including medical residents, fellows, and general practitioners as well as M.D. or Ph.D. post-doctoral research fellows. While comprehensive, we'll attempt to present the material in a manner that simplifies the complex pathophysiologic mechanisms that underlie common fibroproliferative diseases while making it appealing to a broad audience.



Fibrocytes In Health And Disease


Fibrocytes In Health And Disease
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Author : Richard Bucala
language : en
Publisher: World Scientific
Release Date : 2012

Fibrocytes In Health And Disease written by Richard Bucala and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.



Pathogenesis Of Fibrosis


Pathogenesis Of Fibrosis
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Author :
language : en
Publisher:
Release Date : 1994

Pathogenesis Of Fibrosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.




Chronic Inflammation


Chronic Inflammation
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Author : Sashwati Roy
language : en
Publisher: CRC Press
Release Date : 2012-09-17

Chronic Inflammation written by Sashwati Roy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-17 with Medical categories.


Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.



Tissue Repair Contraction And The Myofibroblast


Tissue Repair Contraction And The Myofibroblast
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Author : Christine Chaponnier
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-26

Tissue Repair Contraction And The Myofibroblast written by Christine Chaponnier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-26 with Science categories.


Tissue Repair, Contraction and the Myofibroblast summarizes the latest findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. Coverage shows that the myofibroblast is responsible for the development of hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma. Reviews the cell biology and pathology of the myofibroblast as well as mechanisms of fibrosis evolution in many organs and tissues.



Connective Tissues


Connective Tissues
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Author : Fritz Hartmann
language : en
Publisher:
Release Date : 1974

Connective Tissues written by Fritz Hartmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Connective tissues categories.




Inflammation In Heart Failure


Inflammation In Heart Failure
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Author : Matthijs Blankesteijn
language : en
Publisher: Academic Press
Release Date : 2014-12-05

Inflammation In Heart Failure written by Matthijs Blankesteijn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-05 with Medical categories.


Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases



Chronic Rhinosinusitis


Chronic Rhinosinusitis
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Author : Wytske J. Fokkens
language : en
Publisher: Immunology and Allergy Clinics
Release Date : 2009

Chronic Rhinosinusitis written by Wytske J. Fokkens and has been published by Immunology and Allergy Clinics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.


This issue will focus on treatments for Chronic Rhinosinusitis. Dr. Wyste Fokkens guest edits topics such as: "Inflammatory mechanisms in chronic rhinosinusitis with or without nasal polyposis," "European versus Asian Chronic rhinosinusitis. What did it teach us and what do we want to know," "Epithelium, cilia and mucus, their importance in chronic rhinosinusitis Noam Cohen Noam," "Aspirin intolerance: does desensitization alter the course of the disease," "Anti-inflammatory effects of macrolides: applications in CRS," and more!