Fibrous Proteins Structures And Mechanisms


Fibrous Proteins Structures And Mechanisms
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Fibrous Proteins Structures And Mechanisms


Fibrous Proteins Structures And Mechanisms
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Author : David A.D. Parry
language : en
Publisher: Springer
Release Date : 2017-01-18

Fibrous Proteins Structures And Mechanisms written by David A.D. Parry and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-18 with Science categories.


This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the α-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all α-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology. Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the β-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications. Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials.



Fibrous Proteins Coiled Coils Collagen And Elastomers


Fibrous Proteins Coiled Coils Collagen And Elastomers
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Author : David A.D. Parry
language : en
Publisher: Gulf Professional Publishing
Release Date : 2005-05-06

Fibrous Proteins Coiled Coils Collagen And Elastomers written by David A.D. Parry and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-06 with Science categories.


Fibrous Protein: Coiled-Coils, Collagen and Elastomers is the first of a three-part series on Fibrous Proteins. The books are based on a very successful workshop in Alpbach, Austria on the general topic of Fibrous Proteins that gave rise to the award winning issue of Journal of Structural Biology. Part II will contain an extensive discussion of Molecular Motors and Muscle, Part III on Amyloids, Prions and Beta Proteins. Advances in Protein Chemistry is available online on ScienceDirect - full-text online of volumes 53 onwards. Reveals new structural and functional aspects of fibrous proteins Based on Fibrous Protein workshop in Alpbach, Austria that gave rise to 2003 Nobel Prize winners in Chemistry



Fibrous Protein Structure


Fibrous Protein Structure
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Author : John Squire
language : en
Publisher:
Release Date : 1987

Fibrous Protein Structure written by John Squire and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Science categories.


Fibrous proteins; Fibre diffraction methods; Electron microscopical methods for studies of sections and isolated particles; Three-dimensional image processing methods for electron micrographs; Synthetic polypeptides; Fibrous protein structure and sequence analysis; Collagen and elastin; Intermediate filaments; Microtubules; The myosin molecule; Actin filaments: images and models; Myosin filaments; The cytoskeleton: selected tropics; Molluscan paramyosin filaments; Muscle myofibril architecture; Fast X-ray diffraction studies of muscle; Muscle mechanics and probes of the crossbridge cycle.



Fibrous Protein Structure


Fibrous Protein Structure
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Author : John M. Squire
language : en
Publisher:
Release Date : 1987

Fibrous Protein Structure written by John M. Squire and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.




Fibrous Proteins


Fibrous Proteins
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Author : Shengjie Ling
language : en
Publisher: Humana
Release Date : 2021-09-02

Fibrous Proteins written by Shengjie Ling and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-02 with Science categories.


This detailed volume explores fibrous proteins widely present in different biological tissues or biological structural materials. The book begins by introducing the structure of representative fibrous proteins, including animal silks, collagen, elastin, resilin, and keratin, and it then continues by providing detailed experimental protocols for the synthesis, assembly, and characterization of natural, regenerated, and recombinant fibrous proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Fibrous Proteins: Design, Synthesis, and Assembly is an ideal guide for researchers aiming to master fibrous protein preparations with the aid of this broad and interdisciplinary perspective on understanding the structure-property-function relationships of natural and reconstituted fibrous proteins.



Fibrous Proteins Amyloids Prions And Beta Proteins


Fibrous Proteins Amyloids Prions And Beta Proteins
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Author : John M. Squire
language : en
Publisher: Academic Press
Release Date : 2006-12-22

Fibrous Proteins Amyloids Prions And Beta Proteins written by John M. Squire and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-22 with Science categories.


Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.



Fibrous Proteins


Fibrous Proteins
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Author : Prof. Dr. Thomas Scheibel
language : en
Publisher:
Release Date : 2008

Fibrous Proteins written by Prof. Dr. Thomas Scheibel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Amyloid categories.


Fibrous Proteins will give an overview over some of the most important fibrous proteins including amyloids, collagens, fibrin, flagella, intermediate filaments, microtubules, silks concerning structure and function and possible applications as biomaterials. While our knowledge on globular proteins has been increasing over the past decades, fibrillar proteins have not entered center stage until recently. In general, research of fibrillar proteins has developed in recent years into a very exciting one. New technologies have drastically increased the accessibility and analysis of fibrillar proteins in the past years. With this book we draw attention to this highly fascinating topic of protein science. The book is aimed for an audience of graduate students and scientists and will provide the opportunity to highlight the field of fibrous proteins.



Fibrous Proteins


Fibrous Proteins
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Author : Prof. Dr. Thomas Scheibel
language : en
Publisher: CRC Press
Release Date : 2008-10-21

Fibrous Proteins written by Prof. Dr. Thomas Scheibel and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-21 with Science categories.


Fibrous Proteins will give an overview over some of the most important fibrous proteins including amyloids, collagens, fibrin, flagella, intermediate filaments, microtubules, silks concerning structure and function and possible applications as biomaterials.While our knowledge on globular proteins has been increasing over the past decades, fibrillar



Conformation In Fibrous Proteins And Related Synthetic Polypeptides


Conformation In Fibrous Proteins And Related Synthetic Polypeptides
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Author : R Fraser
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Conformation In Fibrous Proteins And Related Synthetic Polypeptides written by R Fraser and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Conformation in Fibrous Proteins: And Related Synthetic Polypeptides provides a comprehensive and critical account of conformation in fibrous proteins and synthetic polypeptides in the solid state. Physical methods of determining conformation are discussed, and relevant results from studies of synthetic polypeptides and fibrous proteins are presented. Comprised of 18 chapters divided into three sections, this book opens with a discussion on the theory and technique of X-ray diffraction applicable to the study of conformation in fibrous materials, along with electron diffraction, electron microscopy, optical diffraction, and infrared spectrophotometry. The procedures used for conformation analysis and prediction are also outlined. The following chapters consider optimization techniques and other methods for elucidating conformation in fibrous proteins and synthetic polypeptides; the use of synthetic polypeptides as models of fibrous proteins; and conformation in fibrous proteins such as silks, collagens, myofibrillar proteins, and keratins. This monograph will be a valuable source of information for molecular biologists.



Protein Folding


Protein Folding
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Author : Charis Ghelis
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Protein Folding written by Charis Ghelis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Protein Folding aims to collect the most important information in the field of protein folding and probes the main principles that govern formation of the three-dimensional structure of a protein from a nascent polypeptide chain, as well as how the functional properties appear. This text is organized into three sections and consists of 15 chapters. After an introductory chapter where the main problems of protein folding are considered at the cellular level in the context of protein biosynthesis, the discussion turns to the conformation of native globular proteins. Definitions and rules of nomenclature are given, including the structural organization of globular proteins deduced from X-ray crystallographic data. Folding mechanisms are tentatively deduced from the observation of invariants in the architecture of folded proteins. The next chapters focus on the energetics of protein conformation and structure, indicating the principles of thermodynamic stability of the native structure, along with theoretical computation studies of protein folding, structure prediction, and folding simulation. The reader is also introduced to various experimental approaches; the reversibility of the unfolding-folding process; equilibrium and kinetic studies; and detection and characterization of intermediates in protein folding. This text concludes with a chapter dealing with problems specific to oligomeric proteins. This book is intended for research scientists, specialists, biochemists, and students of biochemistry and biology.