Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Mahendra Rai
language : en
Publisher: Elsevier
Release Date : 2025-02-18
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Mahendra Rai and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-18 with Medical categories.
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery. - Presents four new chapters and special focus on plant-based nanoparticles - Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development - Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells, and more - Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : M.L. Faleiro
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by M.L. Faleiro and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
Aromatic and medicinal plants, through their secondary metabolism, provide a complex mixture of volatile molecules known as essential oils. These volatile molecules exert antibacterial activity that has been used in folk medicine for centuries. During the last few decades, the emergence of antibacterial resistance has forced us to search for new and efficient antimicrobial agents. The significant number of studies on the use of essential oils and their components against multidrug-resistant bacteria, such as Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus, Mycobacterium tuberculosis, and Pseudomonas aeruginosa show the exceptional potential of these natural products to curb the development of antibacterial resistance. Moreover, the use of essential oils and their components in combination with antibiotics may increase bacterial susceptibility, thus limiting resistance.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Lyndy McGaw
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Lyndy McGaw and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
Many bacterial diseases affect animals, causing important economic losses in livestock. Subtherapeutic antibiotic use in production animals as antibiotic growth promoters has been implicated as a causative factor in the development of resistance of bacterial pathogens toward several classes of antimicrobials, some of which are used therapeutically in humans. This has led to the banning of antibiotic growth promoters by the European Union, and such a precedent may be followed in other countries. Alternatives to antibiotic growth promoters are necessary to enable the production of animal protein to keep pace with the expanding world population. One approach is to use plant extracts or essential oils as supplements to provide beneficial effects, including direct antibacterial activity and stimulation of the immune system, or enhancement of ruminal digestion. The risk of resistance developing to a combination of phytochemicals is lower than the risk of resistance against a single antibiotic, and synergistic effects of plant constituents may contribute to the overall activity of the preparation.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : T.O. Lawal
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by T.O. Lawal and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
High prevalence of multidrug-resistant microorganisms in the etiologic structure of different infectious processes significantly decreases the effectiveness of the treatment and enhances the probability of an unfavorable outcome from the infection. Combinations between antibiotics and other antimicrobial agents represent one of the most promising approaches for combating multidrug-resistant bacteria. A high therapeutic potential exists for combinations of antibiotics and natural antimicrobial substances with complex mechanisms of action and multiple healing properties, such as plant essential oils. The purpose of the present chapter is to review published studies on antibiotic-essential oil combinations and discuss the prospects for future studies. In general, many studies have shown the potential for essential oils to act synergistically with antibiotics in vitro. The main proposed mechanism of this beneficial effect is through inhibition of efflux pumps by some essential oils, which restores the activity of the antibiotic. Future efforts should be directed into further studies of antibiotic-essential oil combinations against multidrug-resistant bacteria, with an emphasis on understanding the mechanisms of the produced effect. Combinations of essential oils with different types of antimicrobial agents, such as bacteriophages, nanoparticles, and quorum-sensing inhibitors, require greater attention and are worthy of future investigations.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Victor Kuete
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Victor Kuete and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
The development of vancomycin resistance by some microbial strains has made the treatment of some infections more difficult and, in many cases, impossible. Although the search for new drugs against vancomycin-resistant organisms has been very successful, resistance can arise against many of these compounds. Natural products are an invaluable source of a diversity of biologically active compounds for addressing the challenges facing drug development initiatives to combat vancomycin-resistant enterococcal infections. Despite the fact that scientific data on plant metabolites active against vancomycin-resistant enterococci remain scarce, some compounds (including terpenoids and phenolics) have been reported to have inhibitory effects at various levels. This chapter describes the state of the art of research into plant bioactive metabolites against vancomycin-resistant enterococci, highlighting the hit compounds.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Adil M. Allahverdiyev
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Adil M. Allahverdiyev and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
Herpes simplex virus (HSV) infections comprise one of the most important health problems worldwide. HSV-1 and HSV-2 that are the types most frequently seen in disease, manifested by sores and blisters on the mouth, tongue, skin, and genitals of infected individuals. Moreover, herpetic infections can reach life-threatening levels; for instance, HSV-2 prevalence has increased greatly in human immunodeficiency virus-positive patients. This indicates that the herpetic infection could be a major cause of morbidity in immunosuppressed patients. Unfortunately, resistance against antiherpetic drugs has recently been reported. Therefore there is an immediate need to search for new antiviral agents in order to cope with HSV infections. Recently, it has been demonstrated that traditional medicinal plants have strong antiviral activity and some are already being used in the treatment of viral infections, including herpes simplex infections. Accordingly, this chapter aims to present published information on various herbal compounds, investigate the antiherpetic effectiveness of these compounds, and determine the potential of plants as herpetic treatments in the future.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Maria de las Mercedes Oliva
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Maria de las Mercedes Oliva and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
The genus Candida comprises more than 200 species, but few of them have been associated with human infections. C. albicans is the most important cause of disease. Other species such as C. dubliniensis, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis, and C. tropicalis are also being increasingly recognized as significant human pathogens. In recent years, the number of clinical infections caused by Candida species worldwide has risen considerably, and the incidence of resistance to traditional antifungal therapies is also increasing. There is an exigent need for novel antifungal remedies, and plants remain a vital source of these new substances, especially in low-resource countries. Natural compounds are potential antimycotic agents either in their nascent form or as template structures for more effective derivatives. The data and studies described in this chapter document the antimicrobial activity of plant extracts and essential oils against Candida species and show that medicinal plants can be a rich source of potential antifungal compounds.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : M. Fawzi Mahomoodally
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by M. Fawzi Mahomoodally and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
Infectious diseases are responsible for one in every two deaths in many developing countries, but people in sub-Saharan Africa are particularly vulnerable, as poverty is rampant and access to health care is limited. Additionally, the unregulated use of antibiotics in some parts of Africa has led to the emergence of resistance in pathogens. Indeed, one of the biggest pandemics is malaria, which kills millions annually. Currently, artemisinin (effective against chloroquine-resistant Plasmodium) is the only weapon available to fight this pandemic, yet the World Health Organization has reported with concern that some countries in Southeast Asia are beginning to witness resistance to artemisinin. As a consequence, increasing attention is being drawn to botanicals, as they have the potential to provide alternative and complementary therapies, as well as potential leads to address emerging infections and resistance. This chapter will review some medicinal plants from the African Herbal Pharmacopoeia that show promise for containing existing and emerging infectious diseases.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Clarissa Campos Barbosa de Castro
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Clarissa Campos Barbosa de Castro and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
Schistosomiasis is a neglected tropical disease that affects more than 240 million individuals throughout the world. Praziquantel and oxamniquine are the only drugs available for the control of schistosomiasis. Our dependence on just two drugs and concerns about tolerance and/or resistant schistosome strains emphasize the need for developing new schistosomicidal drugs. This chapter summarizes recent reports about schistosomicidal activity of natural products against Schistosoma species. The in vitro and in vivo effects of a number of crude plant extracts, essential oils, and several secondary metabolites (including alkaloids, flavonoids, and lignans) on schistosoma are summarized and discussed. Particular emphasis is placed on in vivo studies and on works describing the direct in vitro effects of natural products on the parasite (schistosomula and adult stages). Some interesting results with promising samples have already been obtained, but more research is required to discover an ideal natural schistosomicidal lead candidate.
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components
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Author : Kateryna Volodymyrivna Kon
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-05-24
Fighting Multidrug Resistance With Herbal Extracts Essential Oils And Their Components written by Kateryna Volodymyrivna Kon and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-24 with Medical categories.
High prevalence of multidrug-resistant microorganisms in the etiologic structure of different infectious processes significantly decreases the effectiveness of the treatment and enhances the probability of an unfavorable outcome from the infection. Combinations between antibiotics and other antimicrobial agents represent one of the most promising approaches for combating multidrug-resistant bacteria. A high therapeutic potential exists for combinations of antibiotics and natural antimicrobial substances with complex mechanisms of action and multiple healing properties, such as plant essential oils. The purpose of the present chapter is to review published studies on antibiotic-essential oil combinations and discuss the prospects for future studies. In general, many studies have shown the potential for essential oils to act synergistically with antibiotics in vitro. The main proposed mechanism of this beneficial effect is through inhibition of efflux pumps by some essential oils, which restores the activity of the antibiotic. Future efforts should be directed into further studies of antibiotic-essential oil combinations against multidrug-resistant bacteria, with an emphasis on understanding the mechanisms of the produced effect. Combinations of essential oils with different types of antimicrobial agents, such as bacteriophages, nanoparticles, and quorum-sensing inhibitors, require greater attention and are worthy of future investigations.