First Conference On Dna Topoisomerases In Cancer Chemotherapy
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First Conference On Dna Topoisomerases In Cancer Chemotherapy
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Author :
language : en
Publisher:
Release Date : 1987
First Conference On Dna Topoisomerases In Cancer Chemotherapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Antineoplastic agents categories.
First Conference On Dna Topoisomerases In Cancer Chemotherapy
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Author :
language : en
Publisher:
Release Date : 1987
First Conference On Dna Topoisomerases In Cancer Chemotherapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
First Conference On Dna Topoisomerases In Cancer Chemotherapy
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Author : Conference on DNA Topoisomerases in Cancer Chemotherapy
language : en
Publisher:
Release Date : 1987
First Conference On Dna Topoisomerases In Cancer Chemotherapy written by Conference on DNA Topoisomerases in Cancer Chemotherapy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Antineoplastic agents categories.
First Conference On Dna Topoisomerases In Cancer Chemotherapy
DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1987
First Conference On Dna Topoisomerases In Cancer Chemotherapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Antineoplastic agents categories.
First Conference On Dna Topoisomerases In Cancer Chemotherapy
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Author : Milan Potmesil
language : en
Publisher:
Release Date : 1987
First Conference On Dna Topoisomerases In Cancer Chemotherapy written by Milan Potmesil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Cancer categories.
Conference On Dna Topoisomerases In Cancer Chemotherapy
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Author : Milan Potmesil
language : en
Publisher:
Release Date : 1987
Conference On Dna Topoisomerases In Cancer Chemotherapy written by Milan Potmesil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with categories.
Molecular Biology Of Dna Topoisomerases And Its Application To Chemotherapy
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Author : Toshiwo Andoh
language : en
Publisher: CRC Press
Release Date : 1992-10-26
Molecular Biology Of Dna Topoisomerases And Its Application To Chemotherapy written by Toshiwo Andoh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-26 with Medical categories.
Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy is based on conference proceedings from the International Symposium on DNA Topoisomerases in Chemotherapy, held in Nagoya, Japan, in November 1991. The book opens with a discussion of the structural and functional properties of various types of DNA topoisomerases identified in prokaryotes and eukaryotes, in addition to their roles as cellular targets of anticancer and antimicrobial agents. Other topics addressed include the genetics and biology of DNA topoisomerases, inhibitors of microbial DNA topoisomerases and drug resistance, inhibitors of mammalian DNA topoisomerases and drug resistance, and preclinical and clinical studies of DNA topoisomerase inhibitors. Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy will broaden the understanding of biology and genetics of DNA topoisomerases and contribute to the development of antimicrobial and anticancer agents-inhibitors of topoisomerases. It will be invaluable for oncologists, molecular biologists, cellular biologists, geneticists, biochemists, and pharmaceutical researchers.
Dna Topoisomerases In Cancer Therapy
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Author : Toshiwo Andoh
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-06-30
Dna Topoisomerases In Cancer Therapy written by Toshiwo Andoh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-30 with Medical categories.
This volume commemorates the 30th anniversary of the discovery in 1971 of the first DNA topoisomerases, i.e topoisomerase I in E. coli, then provisionally named `omega' protein, by the pioneering work of Jim Wang at Harvard University, who has contributed an article to this volume: `Reflections on an accidental discovery' of the enzyme. Many kinds of topoisomerase have since been found from type I through to type VI in a variety of organisms ranging from viruses to higher eukaryote mammals. The wide distribution of enzymes in various forms of life implies that the DNA topoisomerase is essential for life. In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology.
Dna Topoisomerases And Cancer
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Author : Yves Pommier
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-21
Dna Topoisomerases And Cancer written by Yves Pommier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-21 with Medical categories.
DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.
The Fifth Conference On Dna Topoisomerases In Therapy
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Author : New York University. Medical Center
language : en
Publisher:
Release Date : 1994
The Fifth Conference On Dna Topoisomerases In Therapy written by New York University. Medical Center and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Cancer categories.