Five Lipoxygenase Products In Asthma
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Five Lipoxygenase Products In Asthma
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Author : Jeffrey Drazen
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Five Lipoxygenase Products In Asthma written by Jeffrey Drazen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Five-Lipoxygenase Products in Asthma offers an authoritative examination of the biochemistry, basic pharmacology, and clinical pharmacology of the leukotrienes with special emphasis on their role in asthma. A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma highlights agents and products
Lipoxygenases And Their Products
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Author : Stanley Crooke
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Lipoxygenases And Their Products written by Stanley Crooke and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Lipoxygenases and Their Products provides a cogent summary of the advances in understanding lipoxygenases and their products, emphasizing their pharmacology and pathophysiology; regulation and structure; physiological role; and receptors and receptor antagonists. This text also reviews the literature where specific receptor antagonists (as opposed to enzymatic inhibitors) have been used to characterize the pharmacologic action and the pathophysiologic roles of some of lipoxygenase products of arachidonic acid metabolism. This book is organized into 11 chapters and begins with an overview of the biochemical, pharmacological, and pathophysiological aspects of 5-lipoxygenase products of arachidonic acid metabolism in the respiratory, cardiovascular, renal, gastrointestinal, and central nervous systems. The discussion then shifts to human 5-lipoxygenase, emphasizing this enzyme purification, stimulatory factors, and membrane translocation. The reader is methodically introduced to 5-lipoxygenase activity in rats and pigs; the potential and therapeutic value of 5-lipoxygenase inhibitors; the distribution of 15-lipoxygenase in cells or tissues; and products formed through the 15-lipoxygenase pathway. This book also considers lipoxins and third-generation peptidoleukotriene receptor antagonists, and then concludes with a summary of the physiological and pathophysiological effects of leukotrienes and lipoxins in a variety of organs. This book is of interest to scientists interested in arachidonic acid and its metabolites, to scientists engaged in drug discovery-and-development activities in academia and the pharmaceutical industry, and to clinicians interested in diseases associated with leukotrienes and related products.
Lipid Oxidation
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Author : Edwin N. Frankel
language : en
Publisher: Elsevier
Release Date : 2014-01-23
Lipid Oxidation written by Edwin N. Frankel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-23 with Science categories.
In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems. The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease. Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.
Diabetes
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2020-04-24
Diabetes written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-24 with Medical categories.
Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer. Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of diabetes and oxidation issues Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet, its food matrix or plant Includes preclinical, clinical and population studies to help endocrinologists, diabetologists, nutritionists, dieticians and clinicians map out key areas for research and further clinical recommendations
Dietary Interventions In Liver Disease
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Author : Ronald Ross Watson
language : en
Publisher: Academic Press
Release Date : 2019-01-10
Dietary Interventions In Liver Disease written by Ronald Ross Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-10 with Science categories.
Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development. Provides information on agents that affect metabolism and other health-related conditions in the liver Explores the impact of composition, including differences based on country of origin and processing techniques Addresses the most positive results from dietary interventions using bioactive foods to impact liver disease, including reduction of inflammation and improved function
Anesthetic Pharmacology
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Author : Alex S. Evers
language : en
Publisher: Cambridge University Press
Release Date : 2011-03-10
Anesthetic Pharmacology written by Alex S. Evers and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-10 with Medical categories.
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Ion Channel Factsbook
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Author :
language : en
Publisher: Academic Press
Release Date : 1995-11-16
Ion Channel Factsbook written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-11-16 with Science categories.
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for.In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. Nomenclature Expression Sequence analyses Structure and function Electrophysiology Pharmacology Information retrieval
Chronic Obstructive Pulmonary Disease
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Author : Robert A. Stockley
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Chronic Obstructive Pulmonary Disease written by Robert A. Stockley and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
The only international clinical textbook for COPD – one of the top 5 causes of death and disability worldwide The only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatment International team of contributors covers all aspects of COPD – from physiology and epidemiology to diagnosis and treatment Everything the busy physician needs to understand, diagnose and treat the COPD patient: Structure and physiology of the respiratory system Clinical considerations and allied conditions Therapy (including current and developing treatments) Diagnostic tests used in daily practice
Lipoxygenases In Inflammation
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Author : Dieter Steinhilber
language : en
Publisher: Springer
Release Date : 2016-04-27
Lipoxygenases In Inflammation written by Dieter Steinhilber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-27 with Medical categories.
Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.
Personalizing Asthma Management For The Clinician
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Author : Stanley J. Szefler
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-09-22
Personalizing Asthma Management For The Clinician written by Stanley J. Szefler and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-22 with Medical categories.
Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. Prepares you to meet your patients’ needs regarding asthma exacerbation prevention and asthma prevention. Consolidates today’s available information and guidance in this timely area into one convenient resource.