Fixing Genes And Treating Disease
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Gene Therapy
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Author : Joseph Panno
language : en
Publisher: Infobase Publishing
Release Date : 2005
Gene Therapy written by Joseph Panno and has been published by Infobase Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Biology categories.
Many diseases are caused by a simple point mutation.
Fixing Genes And Treating Disease
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Author : Maria Kefalas
language : en
Publisher: Archway Publishing
Release Date : 2021-06-17
Fixing Genes And Treating Disease written by Maria Kefalas and has been published by Archway Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-17 with Science categories.
This book is for families, patients, medical professionals and the patient advocacy community. It discusses the history and science of gene therapy in a manner young children can understand.
Correcting The Code
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Author : Larry Thompson
language : en
Publisher:
Release Date : 1994
Correcting The Code written by Larry Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Medical categories.
"When Dr. French Anderson, researcher and physician at the National Institutes of Health, assembled the team that injected a young girl from the suburbs of Cleveland with a special solution of white blood cells, he ushered in a brave new world of science and medicine. Those cells were genetically altered - or corrected - to produce a critical enzyme necessary to create a fully functioning immune system, which his young patient was born without. The age of human gene therapy had arrived. Along with it will come the molecular cures for cancers and heretofore incurable conditions such as cystic fibrosis, perhaps even AIDS." "Correcting the Code is the eminently readable and remarkable story of the handful of doctors and researchers who deeply believed they could break one of the last barriers in medicine: repairing human genes that cause illnesses. Even before Watson and Crick successfully modeled DNA, the idea of changing the genetic composition of humans had long been a scientific Holy Grail - despite the stain of eugenics and the public phobia of genetic engineering gone amok. Over the last twenty years, as the pace of research has accelerated, laboratories have entered a sort of race to claim the final breakthrough, to be the first to successfully treat a human patient. The story of that frenzied research contains the great scientific upheavals in the field of biology, including a new understanding of how specific molecules interact to compose living cells that make up the human body." "This is the riveting account of how a great scientific puzzle - finding a way to repair actual human molecules - was solved, of the intellectual and political milieu in which it occurred, and of the remarkable people who committed their lives to the task - Anderson, Michael Blaese, Ken Culver, Richard Mulligan, and others." "Author Larry Thompson makes the seemingly indecipherable world of genetic science understandable to the general reader. Furthermore, he unravels a dramatic story of inspired invention, frustrating dead ends, the clash of egos, the fits and starts of innovation that reveal how science is conducted in the real world."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Crispr Cas9 Based Genome Editing For Treating Genetic Disorders And Diseases
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Author : Luis María Vaschetto
language : en
Publisher: CRC Press
Release Date : 2022-01-31
Crispr Cas9 Based Genome Editing For Treating Genetic Disorders And Diseases written by Luis María Vaschetto and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-31 with Mathematics categories.
The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases is a unique reading material for college students, academicians, and other health professionals interested in learning about the broad range of applications of CRISPR/Cas9 genetic scissors. Some topics included in this book are: the role of the CRISPR/Cas9 system in neuroscience, gene therapy, epigenome editing, genome mapping, cancer, virus infection control strategies, regulatory challenges and bioethical considerations.
Heritable Human Genome Editing
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Author : The Royal Society
language : en
Publisher: National Academies Press
Release Date : 2021-01-16
Heritable Human Genome Editing written by The Royal Society and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-16 with Medical categories.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Gene Therapy For Cancer
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Author : Kelly K. Hunt
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-26
Gene Therapy For Cancer written by Kelly K. Hunt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-26 with Medical categories.
The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.
Gene Therapy
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Author : Clay Farris Naff
language : en
Publisher: Greenhaven Press, Incorporated
Release Date : 2004
Gene Therapy written by Clay Farris Naff and has been published by Greenhaven Press, Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Juvenile Nonfiction categories.
Presents an anthology of signed entries that examines the concepts, history, techniques, and ethics of correcting genes that are responsible for the development of disease, with a chronology listing events from 1859 to 2003.
Gene Therapy Therapeutic Mechanisms And Strategies
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Author : Marvin Walker
language : en
Publisher:
Release Date : 2022-09-20
Gene Therapy Therapeutic Mechanisms And Strategies written by Marvin Walker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-20 with categories.
Gene therapy is a field of medical science that focuses on the genetic modifications of the cells to achieve a therapeutic effect for the treatment of a disease by repairing defective genetic material. The main objective of gene therapy is to fix a genetic disorder at its source. For example, if mutation in a certain gene occurs in an inherited disease which results in the production of a dysfunctional protein, then, gene therapy can be used to incorporate a copy of this gene that is normal and does not contain the mutation, and thus, produces a functional protein. This strategy is used to treat inherited retinal diseases and is also known as gene replacement therapy. This book outlines the therapeutic management and strategies of gene therapy in detail. It traces the progress of this field and highlights some of its key concepts and applications. For someone with an interest and eye for detail, this book covers the most significant topics in the field of gene therapy.
Genetics And The Law Iii
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Author : Aubrey Milunsky
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Genetics And The Law Iii written by Aubrey Milunsky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, ... it was the spring of hope, it was the winter of despair. . . . -Charles Dickens, A Tale of Two Cities Dickens, of course, did not have the contemporary dilemmas of modern genetics in mind. Indeed, we need to remind ourselves how short the history of modern genetics really is. Recognition that genetic traits are carried by deoxyribonucleic acid (DNA) occurred only about 40 years ago. Knowledge of the three-dimensional structure of DNA is only about 30 years old. The correct number of human chromosomes was not deter mined until the mid-1950s, and Down syndrome was recognized only in 1959. It was not until in 1968 that the exact location of a gene was determined on an autosomal chromo some, and the study of genes, rather than their protein products, has been possible for barely a decade.
Curing Genetic Diseases Through Genome Reprogramming
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Author : Gianluca Petris
language : en
Publisher: Elsevier
Release Date : 2021-06-23
Curing Genetic Diseases Through Genome Reprogramming written by Gianluca Petris and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-23 with Science categories.
Curing Genetic Diseases through Genome Reprogramming, Volume 182 captures an historic moment in the field of gene therapy-the dawn of a new age in which the dream of curing genetic diseases has become realizable. The volume presents the most clinically advanced gene therapy and genome editing approaches for the treatment of genetic diseases in specific organs, including difficult therapeutic targets, futuristic ideas of genetic interventions, and large scale human genome repair. An initial chapter addresses the complex ethical aspects involved in the very idea of modifying the human genome. Provides a comprehensive view of gene therapy and genome editing technologies, including epigenetic editing Describes the state-of-the-art and future directions for the treatment of genetic diseases, also considering economical aspects Presents chapters that each give a thorough review of a specific disease, target organ or visionary approach, including ethical considerations