Fixing Your Damaged And Incorrect Genes
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Fixing Your Damaged And Incorrect Genes
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Author : Friedberg Errol C
language : en
Publisher: World Scientific
Release Date : 2019-09-24
Fixing Your Damaged And Incorrect Genes written by Friedberg Errol C and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-24 with Science categories.
Fixing Your Damaged and Incorrect Genes is a book about a well-established biological process called DNA REPAIR. The book describes the multiple and varied biochemical strategies by which damaged or incorrect nucleotides are removed from DNA or are corrected. The book includes multiple figures of notable past and present scientists in the field. The book is uniquely focused on an audience of non-biologists and is written in simple language with minimal use of technical terms. It contains an extensive glossary that provides explanations of key words that readers are encouraged to refer to as they read. Fixing Your Damaged and Incorrect Genes is unique, there being no previously published books for non-biologists on the topic of DNA repair.
Gene Therapy Treating Disease By Repairing Genes
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Author : Joseph Panno
language : en
Publisher:
Release Date : 2005
Gene Therapy Treating Disease By Repairing Genes written by Joseph Panno and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Gene therapy categories.
A compelling examination of this controversial form of treatment that faces close monitoring by the public, the government, and the media. Since the 1990s, scientists have identified several thousand genetic disorders that are known to be responsible for diseases and disorders, including cancer, senility, diabetes, and asthma. Gene therapy attempts to cure these disease by replacing the damaged gene that is causing the problem.
Advances In Medical Biochemistry Genomics Physiology And Pathology
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Author : Raj Bawa
language : en
Publisher: CRC Press
Release Date : 2021-12-22
Advances In Medical Biochemistry Genomics Physiology And Pathology written by Raj Bawa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Medical categories.
The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine’s potential to address health problems from both the patient’s and the provider’s perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.
Learning About Your Genes A Primer For Non Biologists
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Author : Friedberg Errol C
language : en
Publisher: World Scientific
Release Date : 2018-09-18
Learning About Your Genes A Primer For Non Biologists written by Friedberg Errol C and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-18 with Science categories.
Genes were unknowingly discovered in the 19th century by Gregor Mendel, a Czechoslovakian monk. It was later established that genes are made of DNA, a biological compound found in tiny thread-like structures called chromosomes that are located in the nuclei of all cells in our bodies. DNA consists of chains of entities called bases of which there are four in nature. DNA consists of long chains of bases (sometimes referred to as DNA sequences) that are joined in any order, but the precise order and length of which constitute different genes.Many (but not all) genes carry a code called the genetic code, a code that instructs the synthesis (manufacture) of the many hundreds of proteins that we require to survive and execute the many functions of life. The genetic code was deciphered in relatively recent years and is considered one of the most significant discoveries in the history of biology.Genes that encode instructions for the synthesis of proteins and those that regulate the manufacture of proteins comprise a mere two percent of our DNA. Despite our extensive knowledge of biology and the sub-discipline of molecular biology (the study of biology at the molecular level), the function (if any) of the rest of the DNA in our cells is unknown.Research about genes and DNA has in recent years spawned an endeavor referred to as the Human Genome Project, an international collaboration that has successfully determined, stored, and rendered publicly available the sequences of almost all the genetic content of the chromosomes of the human organism, otherwise known as the human genome.DNA sequences that are unique to every person on earth have been discovered (DNA fingherprints) and are now used for identifying criminals. The book relates a specific example of identifying a criminal who murdered two women.This is the first and only book that we are aware of that educates non-biologists about genes. It is written in a style and uses a vocabulary that can be comprehended by the average reader who knows very little if anything about genes.
Replicating And Repairing The Genome From Basic Mechanisms To Modern Genetic Technologies
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Author : Kenneth N Kreuzer
language : en
Publisher: World Scientific
Release Date : 2020-03-16
Replicating And Repairing The Genome From Basic Mechanisms To Modern Genetic Technologies written by Kenneth N Kreuzer and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-16 with Science categories.
Replicating and Repairing the Genome provides a concise overview of the fields of DNA replication and repair. The book is particularly appropriate for graduate students and advanced undergraduates, and scientists entering the field or working in related fields. The breadth of information regarding DNA replication and repair is vast and often difficult to absorb, with terminology that differs between experimental systems and with complex interconnections of these processes with other cellular pathways. This book provides simple conceptual descriptions of replication and repair pathways using mostly generic protein names, laying out the logic for how the pathways function and highlighting fascinating aspects of the underlying biochemical mechanisms and biology. The book incorporates extensive and informative diagrams and figures, as well as descriptions of a number of carefully chosen experiments that had major influences in the field.The process of DNA replication is explained progressively by starting with the system of a simple bacterial virus that uses only a few proteins, followed by the well-understood bacterial (E coli) system, and then culminating with the more complex eukaryotic systems. In the second half of the book, individual chapters cover key areas of DNA repair — postreplication repair of mismatches and incorporated ribonucleotides, direct damage reversal, excision repair, and DNA break repair, as well as the related areas of DNA damage tolerance (including translesion DNA polymerases) and DNA damage responses. The book closes with chapters that describe the huge impact of DNA replication and repair on aspects of human health and on modern biotechnology.
Your Genes Your Health
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Author : Aubrey Milunsky, MD, DSc
language : en
Publisher: Oxford University Press
Release Date : 2011-09-29
Your Genes Your Health written by Aubrey Milunsky, MD, DSc and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-29 with Health & Fitness categories.
New advances in genetics have dramatically expanded our ability to avoid, prevent, diagnose, and treat a wide range of disorders. Now, more than ever, families need to know about these new discoveries, especially as there are some 7,000 rare genetic diseases that afflict about 1 in 12 of us. In Your Genes, Your Health, Aubrey Milunsky provides an invaluable and authoritative guide to what you should know about your genes. Illustrated with poignant family histories that underscore the lifesaving importance of knowing one's family medical history and ethnic origin, the book highlights the importance of recognizing seemingly unrelated disorders in a family as due to the same gene mutation and it outlines the key genetic tests needed for diagnosis, detection of carriers, and prenatal diagnosis. Many genetic disorders are discussed including cancer, heart disease, autism, mental illness, birth defects, neurologic disorders, diabetes, obesity and much more. The message of this book is clear--know your family history, be cognizant of your ethnic origins, seek appropriate consultations, and opt for meaningful genetic tests. Recognition of your risk(s) enables prompt preemptive action. By knowing your genes, you may save your life and the lives of those you love.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Dna Repair Protocols
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Author : Lotte Bjergb K
language : en
Publisher: Humana Press
Release Date : 2016-05-01
Dna Repair Protocols written by Lotte Bjergb K and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-01 with Medical categories.
In its 3rd edition, this Methods in Molecular Biology book covers the eukaryotic response to genomic insult including advanced protocols and standard techniques in the field of DNA repair. Offers expert guidance for DNA repair, recombination, and replication."
Dna Replication Recombination And Repair
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Author : Fumio Hanaoka
language : en
Publisher: Springer
Release Date : 2016-01-22
Dna Replication Recombination And Repair written by Fumio Hanaoka and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-22 with Science categories.
This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.
Genetics
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Author : Carla Mooney
language : en
Publisher: Nomad Press
Release Date : 2014-04-15
Genetics written by Carla Mooney and has been published by Nomad Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-15 with Juvenile Nonfiction categories.
Why do children resemble their parents and siblings? Introducing young readers to the fascinating world of genetics, this educational resource presents the main concepts of the science, including what a chromosome does, how DNA is structured, and how genetic inheritance works. Students learn about new discoveries in the field of genetics and how those discoveries have helped to cure or even prevent certain diseases, as well as examine controversial issues in genetics such as genetically modified foods and stem cell research. Combining inquiry-based, age-appropriate activities with biology, Genetics: Breaking the Code of Your DNA features graphic novel illustrations, fascinating sidebars, and a glossary of important vocabulary to illuminate the complex world of genetics and bring it to life. Projects include building 3D DNA double helix models, extracting DNA, using a Punnet Square to predict an offspring’s probability of inheritance, and evaluating the benefits and risks of genetically engineering a new species. Additional materials include a list of current reference works, websites, and Internet resources. Genetics meets common core state standards in language arts for reading informational text and literary nonfiction and is aligned with Next Generation Science Standards. Guided Reading Levels and Lexile measurements indicate grade level and text complexity.