Flavonoids And Anti Aging
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Flavonoids And Anti Aging
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Author : Karam F.A. Soliman
language : en
Publisher: CRC Press
Release Date : 2023-05-03
Flavonoids And Anti Aging written by Karam F.A. Soliman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-03 with Medical categories.
The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, plays a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases. Flavonoids, on the other hand, through their ability to activate and upregulate Nrf2, can have anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals, functional foods, and pharmaceuticals. The present book Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf2 and flavonoids and their applications in various conditions such as aging, osteoporosis, cardiovascular diseases, and neurodegenerative disease and many other areas. Key Features: Focuses on the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and "WELLNESS" molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoid-based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field, this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2, which is responsible for many different disease conditions due to increased reactive oxidative species in the body caused by some physiological triggers.
Flavonoids And Anti Aging
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Author : Karam F. A. Soliman
language : en
Publisher:
Release Date : 2023
Flavonoids And Anti Aging written by Karam F. A. Soliman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Medical categories.
The nuclear factor erythroid 2-related factor 2 (Nrf2) was described as a master regulator of the cellular antioxidant response. Moreover, many critical biological functions linked to cell viability, metabolism, autophagy, inflammation, immunity, and differentiation have been attributed to Nrf2, which regulates over 600 genes. It is well known that oxidative stress, which Nrf2 can ameliorate, play a key role in many pathologic processes such as aging, obesity, diabetes, cancer, and neurodegenerative diseases. Flavonoids, on the other hand, through their ability to activate and upregulate Nrf2, can have anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties. Flavonoids are an essential ingredient in nutraceuticals, functional foods, and pharmaceuticals. The present book Flavonoids and Antiaging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2 focuses on the interaction between Nrf 2 and flavonoids and their applications in various conditions such as aging, osteoporosis, cardiovascular diseases, and neurodegenerative disease and many other areas. Key Features: Focuses on discussing the mechanisms and use of flavonoids in activating Nrf2 as an anti-aging and "WELLNESS" molecule Provides a specific approach to flavonoid activation of Nrf2 and its implications in aging and various disease conditions and its applications as nutraceuticals Presents flavonoids based functional foods Discusses the flavonoid nutraceuticals market and future trends Written by experts in the field, this book provides a unique approach to understanding the flavonoid activation of the transcription factor Nrf2, which is responsible for many different disease conditions due to increased reactive oxidative species in the body due to some physiological triggers.
Antioxidant And Anti Aging Action Of Plant Polyphenols
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Author : Christophe Hano
language : en
Publisher: MDPI
Release Date : 2020-11-13
Antioxidant And Anti Aging Action Of Plant Polyphenols written by Christophe Hano and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Medical categories.
Polyphenols are plant non-nutrient natural products, or plant secondary metabolites, found in fruits, vegetables and seeds that we consume daily. Their intakes from fruit, vegetables, seeds, and nuts are associated with lower risks of chronic and age-related degenerative diseases. Aging is a dynamic and complex biological process involving multiple actors and subject to a number of genetic and/or environmental influences. The famous free radical theory of aging proposed by Prof. Harman in 1956 states that free radicals lead to oxidative damage, causing cellular dysfunction and physiological decline, and are responsible for aging, with the appearance of degenerative diseases and eventually death. From this hypothesis, antioxidant molecules are capable of slowing down the aging process through the successful scavenging of radical oxygen and nitrogen species. Polyphenols have been shown to prolong the lifespan of different model species operating through a well-conserved antioxidant mechanism. This collection of research and review articles covers the most recent advances in the use of plant polyphenols, ranging from their biological properties and possible functions as medicines, the importance of traditional medicines as a source of inspiration, the rationalization of new uses of plant extracts which lead to applications in modern medicine, the status of modern green-chemistry extraction methods, to some reflections on future prospects.
Antioxidant And Anti Aging Action Of Plant Polyphenols
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Author : Christophe Hano
language : en
Publisher:
Release Date : 2020
Antioxidant And Anti Aging Action Of Plant Polyphenols written by Christophe Hano and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Polyphenols are plant non-nutrient natural products, or plant secondary metabolites, found in fruits, vegetables and seeds that we consume daily. Their intakes from fruit, vegetables, seeds, and nuts are associated with lower risks of chronic and age-related degenerative diseases. Aging is a dynamic and complex biological process involving multiple actors and subject to a number of genetic and/or environmental influences. The famous free radical theory of aging proposed by Prof. Harman in 1956 states that free radicals lead to oxidative damage, causing cellular dysfunction and physiological decline, and are responsible for aging, with the appearance of degenerative diseases and eventually death. From this hypothesis, antioxidant molecules are capable of slowing down the aging process through the successful scavenging of radical oxygen and nitrogen species. Polyphenols have been shown to prolong the lifespan of different model species operating through a well-conserved antioxidant mechanism. This collection of research and review articles covers the most recent advances in the use of plant polyphenols, ranging from their biological properties and possible functions as medicines, the importance of traditional medicines as a source of inspiration, the rationalization of new uses of plant extracts which lead to applications in modern medicine, the status of modern green-chemistry extraction methods, to some reflections on future prospects.
Flavonoids And Their Disease Prevention And Treatment Potential
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Author : H.P. Vasantha Rupasinghe
language : en
Publisher: MDPI
Release Date : 2021-03-29
Flavonoids And Their Disease Prevention And Treatment Potential written by H.P. Vasantha Rupasinghe and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-29 with Science categories.
Flavonoids are ubiquitously present in plant-based foods and natural health products. The molecule of flavonoids is characterized by a 15-carbon skeleton of C6–C3–C6, with the different structural configuration of subclasses. The major subclasses of flavonoids with health-promotional properties are the flavanols or catechins (e.g., epigallocatechin 3-gallate from green tea), the flavones (e.g., apigenin from celery), the flavonols (e.g., quercetin glycosides from apples, berries, and onion), the flavanones (e.g., naringenin from citrus), the anthocyanins (e.g., cyanidin-3-O-glucoside from berries), and the isoflavones (e.g., genistein from soya beans). Scientific evidence has strongly shown that regular intake of dietary flavonoids in efficacious amounts reduces the risk of oxidative stress- and chronic inflammation-mediated pathogenesis of human diseases such as cardiovascular disease, certain cancers, and neurological disorders. The physiological benefits of dietary flavonoids have been demonstrated to be due to multiple mechanisms of action, including regulating redox homeostasis, epigenetic regulations, activation of survival genes and signaling pathways, regulation of mitochondrial function and bioenergetics, and modulation of inflammation response. The role of flavonoids on gut microbiota and the impact of microbial metabolites of flavonoids on optimal health has begun to unravel. The complex physiological modulations of flavonoid molecules are due to their structural diversity. However, some flavonoids are not absorbed well, and their bioavailability could be enhanced through structural modifications and applications of nanotechnology, such as encapsulation. This Special Issue consists of four review articles on flavonoids and 15 original research articles, which cover the latest findings on the role of dietary flavonoids and their derivatives in disease prevention and treatment.
Flavonoids As Nutraceuticals
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Author : Rajesh K. Kesharwani
language : en
Publisher: CRC Press
Release Date : 2024-04-09
Flavonoids As Nutraceuticals written by Rajesh K. Kesharwani and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-09 with Medical categories.
Flavonoids are well-known plant metabolites that have extraordinary properties that can be used for treating health issues. The pharmaceutical importance of flavonoids is due to their anti-depressant, anti-viral, anti-inflammatory, and antioxidant capacities. They are also of great importance when it comes to neuroprotection, cardiovascular disorders, and many types of cancer. Flavonoids are also easily available and produce less harmful side effects than some conventional therapeutics. This new volume examines the growing use of flavonoids for prevention and treatment of diseases and discusses their beneficial mechanisms. Chapters in the volume address diverse uses as anti-aging tools, as anti-inflammatory agents, for treating pregnancy-induced disorders, as a promising tool to combat infection of Covid-19, etc. The book explores their specific therapeutic antiviral potentials, the gene expression by flavonoids, and the role of flavonoids in agriculture.
Plant Derived Bioactives
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Author : Mallappa Kumara Swamy
language : en
Publisher: Springer Nature
Release Date : 2020-05-11
Plant Derived Bioactives written by Mallappa Kumara Swamy and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-11 with Science categories.
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Bioactive Molecules In Food
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Author : Jean-Michel Mérillon
language : en
Publisher: Springer Nature
Release Date : 2019-01-25
Bioactive Molecules In Food written by Jean-Michel Mérillon and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-25 with Technology & Engineering categories.
This reference work provides comprehensive information about the bioactive molecules presented in our daily food and their effect on the physical and mental state of our body. Although the concept of functional food is new, the consumption of selected food to attain a specific effect existed already in ancient civilizations, namely of China and India. Consumers are now more attentive to food quality, safety and health benefits, and the food industry is led to develop processed- and packaged-food, particularly in terms of calories, quality, nutritional value and bioactive molecules. This book covers the entire range of bioactive molecules presented in daily food, such as carbohydrates, proteins, lipids, isoflavonoids, carotenoids, vitamin C, polyphenols, bioactive molecules presented in wine, beer and cider. Concepts like French paradox, Mediterranean diet, healthy diet of eating fruits and vegetables, vegan and vegetarian diet, functional foods are described with suitable case studies. Readers will also discover a very timely compilation of methods for bioactive molecules analysis. Written by highly renowned scientists of the field, this reference work appeals to a wide readership, from graduate students, scholars, researchers in the field of botany, agriculture, pharmacy, biotechnology and food industry to those involved in manufacturing, processing and marketing of value-added food products.
Complementary And Alternative Therapies And The Aging Population
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Author : Ronald Ross Watson
language : en
Publisher: Academic Press
Release Date : 2011-04-28
Complementary And Alternative Therapies And The Aging Population written by Ronald Ross Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.
The major objective of this book is to review in detail health problems occurring with significant frequency in aging adults which are proposed to be treated or ameliorated using nutriceuticals as foods and dietary supplements as well as other complementary and alternative therapies. Chapters primarily focusing on nutrients have been excluded to maintain a focus on complementary and alternative medicine (CAM). The book is divided into three general sections: 1. Nutriceuticals and Botanicals in Health Promotion - including Specific Nutriceuticals Used in Treating Aged; and General Nutraceutical Approaches to Therapy with emphasis on cancer. 2. Non-nutritional CAM Therapies – including Mind-mediated Therapies; and Physically Applied CAM Therapies3. Non-dietary Complementary and Alternative Medicine (CAM) Use and Benefits to the Elderly in Health Identifies the important nutritional requirements of the aging population, and how nutraceuticals and other CAM options affect those Addresses the many disease entities and cancers are found with higher frequency in the aged, including cancer, trauma, or infectious disease that can alter intakes of nutraceutical containing foods and/or requirements for various nutrients. Explores the nutritional materials botanical extracts and components that can have important health promotion benefits and risks, to ensure safe consumption Reviews the frequently used non-traditional and often unproven CAM therapies, beyond nutritional and nutraceutical supplements, including a variety of physical and psychosocial treatments.
Flavonoids
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Author : José Justino
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-08-23
Flavonoids written by José Justino and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Science categories.
Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.