Flavonoids Inflammation And Cancer


Flavonoids Inflammation And Cancer
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Flavonoids Inflammation And Cancer


Flavonoids Inflammation And Cancer
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Author : Hollie Swanson
language : en
Publisher: World Scientific
Release Date : 2015-08-28

Flavonoids Inflammation And Cancer written by Hollie Swanson and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-28 with Medical categories.


This book provides an insightful analysis of the chemopreventive actions of flavonoids. Flavonoids are naturally occurring constituents of plants that have been traditionally used as anti-inflammatory and anti-cancer medicines. In addition, human consumption of vegetables and fruits with high concentrations of flavonoids is associated with decreased cancer mortalities rates. Flavonoids, Inflammation and Cancer presents an in-depth analysis of the mechanisms by which flavonoids are thought to prevent inflammation and the development of GI and steroid-responsive cancers. In addition, the promise and pitfalls associated with using flavonoids as chemopreventive agents are discussed. This book is an invaluable reference for basic and clinical scientists who are interested in exploring the link between nutrition and cancer. Contents:Introduction to Flavonoids and ChemopreventionMechanisms by Which Flavonoids Exert Their Beneficial Anti-cancer EffectsFlavonoids and the Inflammatory ResponseFlavonoids and Cancers of the Gastrointestinal TractFlavonoids and Steroid-responsive CancersSummary and Future Directions Readership: Researchers in the pharmaceutical industry, cancer researchers, immunologists, biochemists, natural product researchers. Key Features:Links the biochemical properties of flavonoids to the events associated with the carcinogenic processExamines both the promise and pitfalls associated with the potential use of flavonoids as chemopreventive therapiesThe results obtained from clinical and preclinical (in vitro and in vivo) studies are compared and contrastedKeywords:Flavonoid;Tumor;Proliferation;Chemoprevention



Flavonoids And Their Disease Prevention And Treatment Potential


Flavonoids And Their Disease Prevention And Treatment Potential
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Author : H.P. Vasantha Rupasinghe
language : en
Publisher: MDPI
Release Date : 2021-03-29

Flavonoids And Their Disease Prevention And Treatment Potential written by H.P. Vasantha Rupasinghe and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-29 with Science categories.


Flavonoids are ubiquitously present in plant-based foods and natural health products. The molecule of flavonoids is characterized by a 15-carbon skeleton of C6–C3–C6, with the different structural configuration of subclasses. The major subclasses of flavonoids with health-promotional properties are the flavanols or catechins (e.g., epigallocatechin 3-gallate from green tea), the flavones (e.g., apigenin from celery), the flavonols (e.g., quercetin glycosides from apples, berries, and onion), the flavanones (e.g., naringenin from citrus), the anthocyanins (e.g., cyanidin-3-O-glucoside from berries), and the isoflavones (e.g., genistein from soya beans). Scientific evidence has strongly shown that regular intake of dietary flavonoids in efficacious amounts reduces the risk of oxidative stress- and chronic inflammation-mediated pathogenesis of human diseases such as cardiovascular disease, certain cancers, and neurological disorders. The physiological benefits of dietary flavonoids have been demonstrated to be due to multiple mechanisms of action, including regulating redox homeostasis, epigenetic regulations, activation of survival genes and signaling pathways, regulation of mitochondrial function and bioenergetics, and modulation of inflammation response. The role of flavonoids on gut microbiota and the impact of microbial metabolites of flavonoids on optimal health has begun to unravel. The complex physiological modulations of flavonoid molecules are due to their structural diversity. However, some flavonoids are not absorbed well, and their bioavailability could be enhanced through structural modifications and applications of nanotechnology, such as encapsulation. This Special Issue consists of four review articles on flavonoids and 15 original research articles, which cover the latest findings on the role of dietary flavonoids and their derivatives in disease prevention and treatment.



Current Aspects Of Flavonoids Their Role In Cancer Treatment


Current Aspects Of Flavonoids Their Role In Cancer Treatment
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Author : Hardeep Singh Tuli
language : en
Publisher: Springer
Release Date : 2019-05-21

Current Aspects Of Flavonoids Their Role In Cancer Treatment written by Hardeep Singh Tuli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-21 with Medical categories.


The book comprehensively introduces readers to various aspects of flavonoids, a category of natural metabolites that exhibits various pharmacological effects. It discusses their chemistry, absorption and metabolism, mechanisms of action and toxicology as well as future perspectives for clinical applications, and also provides detailed insights into their anti-cancer properties, since flavonoids are known to modulate tumor-associated intracellular as well as extracellular signaling pathways. The book also highlights the current research on the health effects of selected flavonoids, and their various roles in cancer prevention and treatment. Lastly, the book elucidates nanotechnology-mediated tools to enhance the bioavailability and solubility of flavonoids to improve their bioactivity and pharmacokinetic parameters.



Advances In Flavonoids For Human Health And Prevention Of Diseases


Advances In Flavonoids For Human Health And Prevention Of Diseases
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Author : Nisha Sharma
language : en
Publisher: CRC Press
Release Date : 2024-01-09

Advances In Flavonoids For Human Health And Prevention Of Diseases written by Nisha Sharma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-09 with Medical categories.


In response to the recent upsurge of interest in the therapeutic potential of medicinal plants, with their promising phenolic compounds, this new book offers an important overview of advances in the applications of flavonoids for health. The book explores the nutritional and pharmacological properties of polyphenols and flavonoids, including their ability to prevent the start and development of diseases and how they aid in the management of several chronic pathological illnesses, including cancer, diabetes, cardiovascular disease, neuro-degenerative illness and aging, pregnancy-induced disorders, and others. Also discussed in depth are the properties, classes, and degrees that formulate a phenolic compound and which subsequently supports the development of drugs/products with health benefits.



Polyphenols Based Nanotherapeutics For Cancer Management


Polyphenols Based Nanotherapeutics For Cancer Management
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Author : Shams Tabrez
language : en
Publisher: Springer Nature
Release Date : 2021-10-01

Polyphenols Based Nanotherapeutics For Cancer Management written by Shams Tabrez and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-01 with Medical categories.


This book reviews the applications of polyphenols in cancer treatment. The initial chapter of the book classifies different polyphenols and discusses their biological and chemical properties. The subsequent chapters then explore the diverse role of polyphenols in modulating signal transduction pathways in cancer including, cellular proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis. This book highlights the usefulness of polyphenol enriched seafood in modulating the anti-tumor and anti-inflammatory cytokine IFN-γ. The book also presents nanoformulation of polyphenol as a promising strategy for their enhanced bioavailability and targeted delivery. Lastly, the book examines the toxicity and safety evaluations of polyphenols as anticancer agents.



Inflammation Oxidative Stress And Cancer


Inflammation Oxidative Stress And Cancer
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Author : Ah-Ng Tony Kong
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Inflammation Oxidative Stress And Cancer written by Ah-Ng Tony Kong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


Increasing scientific evidence suggests that the majority of diseases including cancer are driven by oxidative stress and inflammation, attributed to environmental factors. These factors either drive genetic mutations or epigenetically modify expression of key regulatory genes. These changes can occur as early as gestational fetal development, and



Flavonoids And Their Disease Prevention And Treatment Potential


Flavonoids And Their Disease Prevention And Treatment Potential
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Author : H.P. Vasantha Rupasinghe
language : en
Publisher:
Release Date : 2021

Flavonoids And Their Disease Prevention And Treatment Potential written by H.P. Vasantha Rupasinghe and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.


Flavonoids are ubiquitously present in plant-based foods and natural health products. The molecule of flavonoids is characterized by a 15-carbon skeleton of C6-C3-C6, with the different structural configuration of subclasses. The major subclasses of flavonoids with health-promotional properties are the flavanols or catechins (e.g., epigallocatechin 3-gallate from green tea), the flavones (e.g., apigenin from celery), the flavonols (e.g., quercetin glycosides from apples, berries, and onion), the flavanones (e.g., naringenin from citrus), the anthocyanins (e.g., cyanidin-3-O-glucoside from berries), and the isoflavones (e.g., genistein from soya beans). Scientific evidence has strongly shown that regular intake of dietary flavonoids in efficacious amounts reduces the risk of oxidative stress- and chronic inflammation-mediated pathogenesis of human diseases such as cardiovascular disease, certain cancers, and neurological disorders. The physiological benefits of dietary flavonoids have been demonstrated to be due to multiple mechanisms of action, including regulating redox homeostasis, epigenetic regulations, activation of survival genes and signaling pathways, regulation of mitochondrial function and bioenergetics, and modulation of inflammation response. The role of flavonoids on gut microbiota and the impact of microbial metabolites of flavonoids on optimal health has begun to unravel. The complex physiological modulations of flavonoid molecules are due to their structural diversity. However, some flavonoids are not absorbed well, and their bioavailability could be enhanced through structural modifications and applications of nanotechnology, such as encapsulation. This Special Issue consists of four review articles on flavonoids and 15 original research articles, which cover the latest findings on the role of dietary flavonoids and their derivatives in disease prevention and treatment.



Flavonoids


Flavonoids
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Author : José Justino
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-08-23

Flavonoids written by José Justino and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Science categories.


Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.



Advances In Cancer Research


Advances In Cancer Research
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-09-12

Advances In Cancer Research written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-12 with Medical categories.


Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike



Apigenin And Naringenin


Apigenin And Naringenin
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Author : Nilus M. Stacks
language : en
Publisher: Nova Science Publishers
Release Date : 2015

Apigenin And Naringenin written by Nilus M. Stacks and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Bioflavonoids categories.


Apigenin is one of the most bioactive naturally occurring flavonoids, found in fruits, plant-derived beverages, vegetables, wheat sprouts, and some seasonings. It has been found to possess anti-oxidant, anti-inflammatory, and anti-cancer properties. Naringenin is one of the most studied flavonoids abundant in citrus plants. Naringenin and their derivatives are known to exhibit strong anti-oxidant potential along with plenty of protective effects for the improvement of human health. This book discusses the natural sources, pharmacology and role in cancer prevention of the flavonoids, apigenin and naringenin.