Focus On Homocysteine And The Vitamins


Focus On Homocysteine And The Vitamins
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Focus On Homocysteine And The Vitamins


Focus On Homocysteine And The Vitamins
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Author : Christina Bolander-Gouaille
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-22

Focus On Homocysteine And The Vitamins written by Christina Bolander-Gouaille and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-22 with Medical categories.


During the last 10-12 years, the research on homocysteine has become very active. About 1500 of articles are now published each year on homocysteine and the vitamins involved in its metabolism. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalised by treatment with folate and/or vitamines B12 and B6. Many of these findings therefore directly concern most practitioners. However, if there are good reviews covering single aspects of this research, these are published in specialised journals. The author has realised the difficulties for the practitioner in keeping updated. This second edition has been thoroughly updated and also offers more data on the vitamins. Over 1600 references are made available.



Homocysteine


Homocysteine
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Author : Christina Bolander-Gouaille
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Homocysteine written by Christina Bolander-Gouaille and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


While research on homocysteine and vitamins involved in its metabolism has focused on associations with cardiovascular disease, pregnancy complications and fetal malformations, recent research explores connections between homocysteine metabolism and neuropsychiatric disease, particularly cognitive decline and dementia. If homocysteine-lowering vitamin treatment can reduce the incidence or delay the onset of dementia, the impact would be significant. This book summarises current research, reviews the underlying biochemistry and surveys diagnostic aspects.



Focus On Homocysteine


Focus On Homocysteine
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Author : Christine Bolander-Gouaille
language : en
Publisher: Springer
Release Date : 2013-03-09

Focus On Homocysteine written by Christine Bolander-Gouaille and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


During the last 8-10 years the research on homocysteine has become very active. Hundreds of articles are now published each year. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalized by treatment with folate and/or vitamines B 12 and B 6. Many of these findings therefore directly concern most practitioners. However, if there are good reviews covering single aspects of this research, these are published in specialized journals. The author has realized the difficulties for the practitioner in keeping updated.



Water Soluble Vitamins


Water Soluble Vitamins
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Author : Olaf Stanger
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-27

Water Soluble Vitamins written by Olaf Stanger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-27 with Medical categories.


The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from “vital-amines”, indicates their elementary metabolic key functions in human metabolism. Vitamins are truly families of compounds, which include precursors and various free and bound forms, all with individual roles in metabolism and function. A more recent approach therefore searches for the components, the understanding of their roles in physiology and pathology as well as looking for novel pharmacological applications. When used properly, vitamins are, indeed, “magical” substances. Due to their efficacy, they should therefore be regarded as drugs with effects and side effects to be weighted against each other. Today, it is not the previously fatal deficiency-associated diseases that are in the focus of interest, but rather the relation of suboptimal vitamin bioavailability to chronic disease. This is complicated by genetic susceptibility, lifestyle, and the presence or absence of health-compromising habits, such as smoking. In turn, the development and application of new and more sensitive and specific assays further enable us to look more closely into the many functions of vitamins. Water soluble vitamins are complex molecular structures and even today, many areas in vitamin biochemistry are not yet fully understood. Novel effects and functions of vitamins remain and continue to be discovered. This book presents most recent research results and fascinating new knowledge on the role and effects of the water soluble vitamins in man. Some of the most distinguished chemists, biochemists, biologists and clinicians have contributed valuable chapters sharing unexpected novel insights into the biochemistry, (epi)genetics, metabolism, and function of water soluble vitamins, with their potential for clinical applications. Thus, physicians, clinicians, scientists, researchers, epidemiologists. nutritional specialists and health professionals alike will find stimulating and fascinating new insight in the many roles that water soluble vitamins play in human health and disease.



Homocysteine Ralated Vitamines And Neuropsychiatric Disdorders


Homocysteine Ralated Vitamines And Neuropsychiatric Disdorders
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Author : Steven Finch
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2017-06

Homocysteine Ralated Vitamines And Neuropsychiatric Disdorders written by Steven Finch and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06 with categories.


While research on homocysteine and vitamins involved in its metabolism has focused on associations with cardiovascular disease, pregnancy complications and fetal malformations, recent research explores connections between homocysteine metabolism and neuropsychiatric disease, particularly cognitive decline and dementia. If homocysteine-lowering vitamin treatment can reduce the incidence or delay the onset of dementia, the impact would be significant. This book summarises current research, reviews the underlying biochemistry and surveys diagnostic aspects.



Nutritional Management And Metabolic Aspects Of Hyperhomocysteinemia


Nutritional Management And Metabolic Aspects Of Hyperhomocysteinemia
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Author : Mostafa I. Waly
language : en
Publisher: Springer Nature
Release Date : 2021-03-31

Nutritional Management And Metabolic Aspects Of Hyperhomocysteinemia written by Mostafa I. Waly and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Medical categories.


Elevated blood concentrations of homocysteine, B vitamins deficiencies and oxidative stress are etiological factors for many human chronic diseases, yet the etiologic relationship of hyperhomocysteinemia to these disorders remains poorly understood. Clinical trials continue to support the notion that hyperhomocysteinemia is involved in the pathogenesis of oxidative stress and its associated impairment of cellular redox status. Antioxidants, phytochemicals, and bioactive agents are thought to be associated with the reduction of oxidative stress and reducing risk of chronic diseases, yet their role in preventing hyperhomocysteinemia-mediated oxidative stress has not been well covered in the literature. Nutritional Management and Metabolic Aspects and of Hyperhomocysteinemia comprehensively covers the nutritional-based intervention for combating hyperhomocysteinemia-mediated oxidative stress, metabolic regulation of homocysteine-dependent transulfuration and transmethylation pathways, and the identification of novel biomarkers for early diagnosis of hyperhomocysteinemia. The main goal of this text is to address the biochemical and nutritional aspects of hyperhomocysteinemia in relation to increasing risk of chronic diseases, providing insight into the etiology of hyperhomocysteinemia and covering new research on the effective reduction and management of hyperhomocysteinemia-associated chronic diseases. For researchers seeking a singular source for the understanding of the biochemical aspects and nutrition-based combat of hyperhomocysteinemia, its risk factors, preventive measures, and possible treatments currently available, this text provides all of the important needed information in up-to-date and comprehensive form.



Focus On Homocysteine


Focus On Homocysteine
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Author : Christina Bolander-Gouaille
language : en
Publisher:
Release Date : 2014-01-15

Focus On Homocysteine written by Christina Bolander-Gouaille and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.




Folic Acid


Folic Acid
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Author : Stephen M. Lee
language : en
Publisher:
Release Date : 2017

Folic Acid written by Stephen M. Lee and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medical categories.


This book reviews and discusses the most relevant epidemiological aspects of OFCs and its prevention. It evaluates the role of folate and other factors in preventing OFC by analysing the health and socio-demographic data collected from a population sample. Individuals that are deficient in folates are suggested to have increase vulnerability to disease, including neurological conditions. Folates are involved in the metabolism of homocysteine which is a sulfur containing non-protein amino acid. This book will also highlight the recent advances made in understanding the effect of dietary folic acid over supplementation on neurological function. Patients with low levels of folic acid and other B vitamins, metabolism disorders, and renal failure have frequently high homocysteine levels that have been especially associated with cardiovascular and bone disease. This book reviews and analyzes the most important results about the effects of folic acid supplementation on clinical targets and it focuses on the effects of folic acid therapy on clinical outcomes of chronic renal failure patients with high homocysteine levels.



Homocysteine And Vascular Disease


Homocysteine And Vascular Disease
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Author : K. Robinson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Homocysteine And Vascular Disease written by K. Robinson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


This is an important and timely volume. The history of research in homocysteine metabolism can be divided into three periods. The first phase was the exploration of the individual reactions and metabolites that characterize the transmethylation and transsulfuration sequences. The former originated with his description of the biosynthesis of methylpyridine and culminated in the work of Cantoni and Axelrod. Similarly the finding that insulin contained cystine was a potent catalyst for the metabolic and nutritional studies of Rose and du Vigneaud. The description and the definition of homocystinuria, a rare inherited meta bolic disorder, marked the beginning of the second historical period. Where previously there had been few laboratories located largely in the United States soon there were numerous research groups representing many nationalities. The more intense focus led to major advances, both in the laboratory and in the clinics. Studies of afflicted individuals, when combined with investigations in experimental animals, provided the basis for a concept of methionine metabo lism that encompassed both transmethylation and transsulfuration. The central role of homocysteine was apparent.



B Vitamins And Folate


B Vitamins And Folate
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Author : Victor R. Preedy
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013

B Vitamins And Folate written by Victor R. Preedy and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Health & Fitness categories.


Written by an expert team, this research compilation provides a fascinating insight into the scientific knowledge around these compounds for health and nutritional scientists.