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Folded Selves

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Author : Michelle Burnham
language : en
Publisher: Dartmouth College Press
Release Date : 2014-06-14

Folded Selves written by Michelle Burnham and has been published by Dartmouth College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-14 with History categories.

Folded Selves radically refigures traditional portraits of seventeenth-century New England literature and culture by situating colonial writing within the spatial, transnational, and economic contexts that characterized the early-modern "world system" theorized by Immanuel Wallerstein and others. Michelle Burnham rethinks American literary history and the politics of colonial dissent, and her book breaks new ground in making the economic relations of investment, credit, and trade central to this new framework for early American literary and cultural study. Transcontinental colonialism and mercantile capitalism underwrote not just the emerging world system but New World writing -- suggesting that early modern literary aesthetics and the early modern economy helped to sponsor each other. Burnham locates in New England's literature of dissent -- from Ma-re Mount to the Salem witchcraft trials -- a persistent use of economic language, as well as competing economies of style. The brilliance of Burnham's study is that it exposes the transoceanic material and commercial concerns of colonial America's literature and culture of dissent.

Folding And Self Assembly Of Biological Macromolecules

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Author : Eric Westhof
language : en
Publisher: World Scientific
Release Date : 2004

Folding And Self Assembly Of Biological Macromolecules written by Eric Westhof and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.

This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers - and audience interaction - are edited and illustrated versions of the transcribed oral presentations.

Protein Folding And Self Avoiding Walks Polyhedral Studies And Solutions

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Author : Agnes Dittel
language : en
Publisher: Logos Verlag Berlin GmbH
Release Date : 2008

Protein Folding And Self Avoiding Walks Polyhedral Studies And Solutions written by Agnes Dittel and has been published by Logos Verlag Berlin GmbH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.

The protein folding problem refers to the correlation of a protein's amino acid sequence and its native three-dimensional structure which is essential for functionality. It still constitutes one of the major challenges in computational biology. One commonly studied model for the protein folding problem is the HP lattice model in which proteins are considered in a fairly abstract representation. However, the HP model proteins exhibit significant parallels to proteins occurring in nature. The solution of the HP lattice mode as a combinatorial optimization problem has been proven to be NP-complete, and there have already been developed various different approaches for efficient algorithms. We study an integer programming formulation of the problem. Starting with an analysis of this model, where we concentrate on symmetry issues, we show how the model can be consolidated by exploiting symmetry properties of the underlying lattice. The main focus lies in the development of specific components of a branch-and-cut framework for the computation of solutions for the HP model by means of integer programming methods. In order to understand the structure of the model, we perform a series of polyhedral studies from which we derive two main classes of cutting planes. Furthermore, we exploit the knowledge of folding principles which are also valid for HP model proteins for the development of related branching strategies. For the solution of a special class of instances, we present an implementation of a genetic algorithm for the generation of primal feasible start solutions. Finally, we document the performance of the methods developed for each of the four topics (model consolidation, primal method, branching strategy and cutting planes) within the branch-and-cut procedure. We present computational results for different types of lattices, where we both consider known benchmark instances from literature and random instances.

On Folding

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Author : Michael Friedman
language : en
Publisher: transcript Verlag
Release Date : 2016-05-31

On Folding written by Michael Friedman and has been published by transcript Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Philosophy categories.

It is only recently, with the increasing interest in origami and folding in natural sciences and the humanities, that the fold as a new conception in a whole range of disciplines has begun to be conceived in a broader way. Folding as a material and structural process offers a new methodology to think about the close relationship of matter, form and code. It henceforth crosses out old dichotomies, such as the organic and the inorganic or nature and technology, and blurs the boundaries between experimental, conceptual and historical approaches. This anthology aims to unfold this new interdisciplinary field and its disciplinary impact, ranging from materials science, biology, architecture, and mathematics to literature and philosophy.

Molecular Biology Of Protein Folding Part B

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Author : P. Michael Conn
language : en
Publisher: Academic Press
Release Date : 2009-01-09

Molecular Biology Of Protein Folding Part B written by P. Michael Conn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-09 with Science categories.

Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. Follow the new editor-in-chief, P. Michael Conn, as he introduces this second thematic volume in the series – an in-depth aid to researchers who are looking for the best techniques and tools for understanding the complexities of protein folding Understand the advantages of protein folding over other therapeutic approaches and see how protein folding plays a critical role in the development of diseases such as Alzheimer’s and diabetes Decipher the rules of protein folding through compelling and timely reviews combined with chapters written by international authors in engineering, biochemistry, physics and computer science

The College Of Life Or Practical Self

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Author : Henry Davenport Northrop
language : en
Publisher:
Release Date : 1896

The College Of Life Or Practical Self written by Henry Davenport Northrop and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1896 with African American women categories.

The Folded Clock

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Author : Heidi Julavits
language : en
Publisher: Bloomsbury Publishing
Release Date : 2017-03-09

The Folded Clock written by Heidi Julavits and has been published by Bloomsbury Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-09 with Biography & Autobiography categories.

An insightful meditation on time, relationships and identity, The Folded Clock is a funny, thoughtful and inquisitive diary for fans of Olivia Laing and Jenny Offill Like many young people, Heidi Julavits kept a diary. Decades later she found her old diaries in a storage bin, and hoped to discover the early evidence of the person (and writer) she'd since become. Instead, they 'revealed me to possess the mind of a paranoid tax auditor'. Thus was born a desire to try again, to chronicle her daily life as a fortysomething woman, wife, mother and writer. The dazzling result is The Folded Clock, in which the diary form becomes a meditation on time and self, youth and aging, betrayal and loyalty, friendship and romance, faith and fate, marriage and family, desire and death, gossip and secrets, art and ambition. The Folded Clock is as playful as it is brilliant, a tour de force by one of the most gifted prose stylists in the English language.