Folded Synthetic Peptides For Biomedical Applications


Folded Synthetic Peptides For Biomedical Applications
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Folded Synthetic Peptides For Biomedical Applications


Folded Synthetic Peptides For Biomedical Applications
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Author : Alessandro Contini
language : en
Publisher: Frontiers Media SA
Release Date : 2019-09-26

Folded Synthetic Peptides For Biomedical Applications written by Alessandro Contini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-26 with categories.


Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequential arrangement, induce secondary structures peptides. Such building blocks include D- and other non-proteinogenic amino acids, as well as beta- and gamma-amino acids. This Research Topic comprises a collection of papers by an international group of 77 scientists with a background in synthetic, analytical, computational and medicinal chemistry, as well as in biochemistry and pharmacology. Their research is presented here in a total of 11 papers (8 original research reports and 3 reviews), covering diverse aspects of folded synthetic peptides. These studies include the preparation and characterization of new peptide monomers with interesting folding properties, the synthesis and conformational analysis of non-natural peptides, as well as the use of folded peptidomimetics as molecular switches. Additionally, a range of biomedical applications, such as antimicrobial, anti-inflammatory, antiangiogenic and immune-stimulating activities, are also reported. We hope this eBook will be a source of inspiration and knowledge for scientist in various disciplines related to folded peptides and their many applications, as well as for those who want to learn more about this fascinating field of research.



Peptides And Peptide Based Biomaterials And Their Biomedical Applications


Peptides And Peptide Based Biomaterials And Their Biomedical Applications
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Author : Anwar Sunna
language : en
Publisher: Springer
Release Date : 2017-10-26

Peptides And Peptide Based Biomaterials And Their Biomedical Applications written by Anwar Sunna and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-26 with Science categories.


Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.



Biologically Active Peptides


Biologically Active Peptides
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Author : David B. Weiner
language : en
Publisher: CRC Press
Release Date : 1993-11-04

Biologically Active Peptides written by David B. Weiner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-04 with Medical categories.


Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.



Synthetic Peptides And Peptidomimetics From Basic Science To Biomedical Applications


Synthetic Peptides And Peptidomimetics From Basic Science To Biomedical Applications
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Author : Nunzianna Doti
language : en
Publisher:
Release Date : 2022

Synthetic Peptides And Peptidomimetics From Basic Science To Biomedical Applications written by Nunzianna Doti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.


This Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life.



Synthetic Peptides And Peptidomimetics


Synthetic Peptides And Peptidomimetics
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Author : Nunzianna Doti
language : en
Publisher: Mdpi AG
Release Date : 2022-06-10

Synthetic Peptides And Peptidomimetics written by Nunzianna Doti and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-10 with Science categories.


This Special Issue, entitled "Synthetic Peptides and Peptidomimetics: From Basic Science to Biomedical Applications", has included both reviews and original research contributions focused on the chemical design and biomedical applications of structurally modified bioactive peptides. The papers collected show how successful this class of molecules still is, both as model molecules for studying the structure of proteins and as potential therapeutics and diagnostics, and also as laboratory tools for advanced basic and applied studies. The large scientific community working in this field is in fact very active and productive, and is making the most of the potential and versatility of these molecules to generate increasingly interesting and innovative molecules of therapeutic interest and to understand the fundamental molecular mechanisms of life.



Biologically Active Peptides


Biologically Active Peptides
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Author : David B. Weiner
language : en
Publisher: CRC Press
Release Date : 2023-07-28

Biologically Active Peptides written by David B. Weiner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-28 with Medical categories.


Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.



Peptide Applications In Biomedicine Biotechnology And Bioengineering


Peptide Applications In Biomedicine Biotechnology And Bioengineering
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Author : Sotirios Koutsopoulos
language : en
Publisher: Woodhead Publishing
Release Date : 2017-11-16

Peptide Applications In Biomedicine Biotechnology And Bioengineering written by Sotirios Koutsopoulos and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-16 with Technology & Engineering categories.


Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. Presents a self-contained work for the field of biomedical peptides Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering Covers current and potential applications of biomedical peptides



Peptide Synthesis


Peptide Synthesis
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Author : Jaya Varkey
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18

Peptide Synthesis written by Jaya Varkey and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Science categories.


Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides.



Self Assembled Peptide Nanostructures


Self Assembled Peptide Nanostructures
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Author : Jaime Castillo
language : en
Publisher: CRC Press
Release Date : 2012-11-21

Self Assembled Peptide Nanostructures written by Jaime Castillo and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-21 with Medical categories.


The self-organization of bionanostructures into well-defined functional machineries found in nature has been a priceless source of ideas for researchers. The molecules of life, proteins, DNA, RNA, etc., as well as the structures and forms that these molecules assume serve as rich sources of ideas for scientists or engineers who are interested in developing bio-inspired materials for innovations in biomedical fields. In nature, molecular self-assembly is a process by which complex three-dimensional structures with well-defined functions are constructed, starting from simple building blocks such as proteins and peptides. This book introduces readers to the theory and mechanisms of peptide self-assembly processes. The authors present the more common peptide self-assembled building blocks and discuss how researchers from different fields can apply self-assembling principles to bionanotechnology applications. The advantages and challenges are mentioned together with examples that reflect the state of the art of the use of self-assembled peptide building blocks in nanotechnology.



Biomedical Applications Of Peptide Glyco And Glycopeptide Dendrimers And Analogous Dendrimeric Structures


Biomedical Applications Of Peptide Glyco And Glycopeptide Dendrimers And Analogous Dendrimeric Structures
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Author : Jaroslav Sebestik
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-13

Biomedical Applications Of Peptide Glyco And Glycopeptide Dendrimers And Analogous Dendrimeric Structures written by Jaroslav Sebestik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-13 with Science categories.


Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.