Fraud In The Lab

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Fraud In The Lab
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Author : Nicolas Chevassus-au-Louis
language : en
Publisher: Harvard University Press
Release Date : 2019-08-13
Fraud In The Lab written by Nicolas Chevassus-au-Louis and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Science categories.
From a journalist and former lab researcher, a penetrating investigation of the explosion in cases of scientific fraud and the factors behind it. In the 1970s, a scientific scandal about painted mice hit the headlines. A cancer researcher was found to have deliberately falsified his experiments by coloring transplanted mouse skin with ink. This widely publicized case of scientific misconduct marked the beginning of an epidemic of fraud that plagues the scientific community today. From manipulated results and made-up data to retouched illustrations and plagiarism, cases of scientific fraud have skyrocketed in the past two decades, especially in the biomedical sciences. Fraud in the Lab examines cases of scientific misconduct around the world and asks why this behavior is so pervasive. Nicolas Chevassus-au-Louis points to large-scale trends that have led to an environment of heightened competition, extreme self-interest, and emphasis on short-term payoffs. Because of the move toward highly specialized research, fewer experts are qualified to verify experimental findings. And the pace of journal publishing has exacerbated the scientific rewards system—publish or perish holds sway more than ever. Even when instances of misconduct are discovered, researchers often face few consequences, and falsified data may continue to circulate after an article has been retracted. Sharp and damning, this exposé details the circumstances that have allowed scientific standards to decline. Fraud in the Lab reveals the intense social pressures that lead to fraud, documents the lasting impact it has had on the scientific community, and highlights recent initiatives and proposals to reduce the extent of misconduct in the future.
Plastic Fantastic
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Author : Eugenie Samuel Reich
language : en
Publisher: St. Martin's Press
Release Date : 2009-05-12
Plastic Fantastic written by Eugenie Samuel Reich and has been published by St. Martin's Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-12 with Science categories.
This is the story of wunderkind physicist Jan Hendrik Schön who faked the discovery of a new superconductor made from plastic. A star researcher at the world-renowned Bell Laboratories in New Jersey, he claimed to have stumbled across a powerful method for making carbon-based crystals into transistors, the switches found on computer chips. Had his experiments worked, they would have paved the way for huge advances in technology--computer chips that we could stick on a dress or eyewear, or even use to make electronic screens as thin and easy-to-fold as sheets of paper. But as other researchers tried to recreate Schön's experiments, the scientific community learned that it had been duped. Why did so many top experts, including Nobel prize-winners, support Schön? What led the major scientific journals to publish his work, and promote it with press releases? And what drove Schön, by all accounts a mild-mannered, modest and obliging young man, to tell such outrageous lies?
Science Fictions
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Author : Stuart Ritchie
language : en
Publisher: Arrow
Release Date : 2021-09-16
Science Fictions written by Stuart Ritchie and has been published by Arrow this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-16 with Errors, Scientific categories.
Fostering Integrity In Research
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2018-01-13
Fostering Integrity In Research written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-13 with Science categories.
The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.
Bad Blood
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Author : John Carreyrou
language : en
Publisher: Vintage
Release Date : 2018-05-21
Bad Blood written by John Carreyrou and has been published by Vintage this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-21 with Business & Economics categories.
NATIONAL BESTSELLER • The gripping story of Elizabeth Holmes and Theranos—one of the biggest corporate frauds in history—a tale of ambition and hubris set amid the bold promises of Silicon Valley, rigorously reported by the prize-winning journalist. With a new Afterword covering her trial and sentencing, bringing the story to a close. “Chilling ... Reads like a thriller ... Carreyrou tells [the Theranos story] virtually to perfection.” —The New York Times Book Review In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the next Steve Jobs: a brilliant Stanford dropout whose startup “unicorn” promised to revolutionize the medical industry with its breakthrough device, which performed the whole range of laboratory tests from a single drop of blood. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.5 billion. There was just one problem: The technology didn’t work. Erroneous results put patients in danger, leading to misdiagnoses and unnecessary treatments. All the while, Holmes and her partner, Sunny Balwani, worked to silence anyone who voiced misgivings—from journalists to their own employees.
The Baltimore Case A Trial Of Politics Science And Character
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Author : Daniel J. Kevles
language : en
Publisher: W. W. Norton & Company
Release Date : 2000-01-17
The Baltimore Case A Trial Of Politics Science And Character written by Daniel J. Kevles and has been published by W. W. Norton & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-17 with Science categories.
"You read with a rising sense of despair and outrage, and you finish it as if awakening from a nightmare only Kafka could have conceived."--Christopher Lehmann-Haupt, New York Times David Baltimore won the Nobel Prize in medicine in 1975. Known as a wunderkind in the field of immunology, he rose quickly through the ranks of the scientific community to become the president of the distinguished Rockefeller University. Less than a year and a half later, Baltimore resigned from his presidency, citing the personal toll of fighting a long battle over an allegedly fraudulent paper he had collaborated on in 1986 while at MIT. From the beginning, the Baltimore case provided a moveable feast for those eager to hold science more accountable to the public that subsidizes its research. Did Baltimore stonewall a legitimate government inquiry? Or was he the victim of witch hunters? The Baltimore Case tells the complete story of this complex affair, reminding us how important the issues of government oversight and scientific integrity have become in a culture in which increasingly complicated technology widens the divide between scientists and society.
The Laboratory Of The Mind
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Author : James Robert Brown
language : en
Publisher: Psychology Press
Release Date : 1993
The Laboratory Of The Mind written by James Robert Brown and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Philosophy categories.
An investigation into the philosophical implications of thought experiments in science. Brown provides a fascinating account of some of the most influential thought experiments in the history of science.
Intuition
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Author : Allegra Goodman
language : en
Publisher: Atlantic Books Ltd
Release Date : 2010-08-01
Intuition written by Allegra Goodman and has been published by Atlantic Books Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-01 with Fiction categories.
LONGLISTED FOR THE ORANGE PRIZE FOR FICTION 2009 SHORTLISTED FOR THE WELLCOME TRUST BOOK PRIZE 2009 A charismatic doctor and a rigorous scientist are co-directors of a cancer research lab. They demand nothing less than complete dedication and obedience from their young protégés. In this high-pressure setting, one young man's experiments begin to show exciting results. At first the entire lab is giddy with expectation. But his colleagues become suspicious, and soon an all-too-public controversy engulfs the lab and everyone in it... Intuition is a rich and compelling human drama about the quest for 'truth', that asks: who can you trust when you aren't even sure you can trust yourself?
Fraud And Abuse Among Clinical Laboratories
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Author : United States. Congress. Senate. Special Committee on Aging. Subcommittee on Long-Term Care
language : en
Publisher:
Release Date : 1976
Fraud And Abuse Among Clinical Laboratories written by United States. Congress. Senate. Special Committee on Aging. Subcommittee on Long-Term Care and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Fraud categories.
Evolution Of Translational Omics
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-09-13
Evolution Of Translational Omics written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-13 with Science categories.
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.