Free Energy Transduction And Biochemical Cycle Kinetics
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Free Energy Transduction And Biochemical Cycle Kinetics
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Author : Terrell L. Hill
language : en
Publisher: Courier Corporation
Release Date : 2013-01-09
Free Energy Transduction And Biochemical Cycle Kinetics written by Terrell L. Hill and has been published by Courier Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-09 with Science categories.
This three-part treatment translates the technical language of research monographs on the theory of free energy transfer in biology, making the subject more accessible to those entering the field. Designed for upper-level classes in biochemistry or biophysics, it can also be used for independent study. 36 figures. 1989 edition.
Free Energy Transduction In Biology
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Author : Terrell Hill
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Energy Transduction In Biology written by Terrell Hill and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Energy Transduction in Biology: The Steady-State Kinetic and Thermodynamic Formalism focuses on the steady-state kinetic and thermodynamic formalism related to free energy transduction. As the word ""formalism"" implies, the discussion concerns general principles and methods and not details of proposed mechanisms in the various special cases. Organized into seven chapters, this book first describes the diagram method, which is the main analytical tool in the study of discrete state, cycling system. The next chapter describes the essential topic of cycles and cycle fluxes. Some chapters discuss the more important bioenergetic principles that emerge from the diagram approach. This book is also concerned with somewhat more specialized aspects of the subject (stochastics and fluctuations) and interacting subsystems and multienzyme complexes, including oxidative phosphorylation.
Thermodynamics And Control Of Biological Free Energy Transduction
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Author : Hans V. Westerhoff
language : en
Publisher: Elsevier Publishing Company
Release Date : 1987
Thermodynamics And Control Of Biological Free Energy Transduction written by Hans V. Westerhoff and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Science categories.
This book contains a description of how quantitative notions from physics and chemistry may be applied to biological systems, in particular those involved in biological free energy transduction. Researchers in the fields of bioenergetics and biochemistry will find this volume to be an excellent, in-depth review of the subject and an invaluable source of information.
Enzyme Kinetics
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Author : Arthur R. Schulz
language : en
Publisher: Cambridge University Press
Release Date : 1994-11-25
Enzyme Kinetics written by Arthur R. Schulz and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-11-25 with Medical categories.
This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which constitute metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. Algorithms are developed which can be implemented in computer programs for the derivation of equations. The treatment of steady-state enzyme kinetics is extended to allosteric enzymes and subunit interactions in polymeric enzymes. Principles are presented which provide for mathematical analysis of the control of multi-enzyme systems. Problems are included at the end of each chapter and their solutions are found at the end of the book. This book will be a useful text for advanced undergraduates and graduate students taking courses in enzyme chemistry and enzyme kinetics.
Hierarchical Genome And Differentiation Waves The Novel Unification Of Development Genetics And Evolution In 2 Volumes
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Author : Gordon Richard
language : en
Publisher: World Scientific
Release Date : 1999-07-12
Hierarchical Genome And Differentiation Waves The Novel Unification Of Development Genetics And Evolution In 2 Volumes written by Gordon Richard and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-07-12 with Science categories.
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
Kinetics Of Enzyme Modifier Interactions
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Author : Antonio Baici
language : en
Publisher: Springer
Release Date : 2015-06-24
Kinetics Of Enzyme Modifier Interactions written by Antonio Baici and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-24 with Science categories.
The kinetic mechanisms by which enzymes interact with inhibitors and activators, collectively called modifiers, are scrutinized and ranked taxonomically into autonomous species in a way similar to that used in the biological classification of plants and animals. The systematization of the mechanisms is based on two fundamental characters: the allosteric linkage between substrate and modifier and the factor by which a modifier affects the catalytic constant of the enzyme. Combinations of the physically significant states of these two characters in an ancestor-descendant-like fashion reveal the existence of seventeen modes of interaction that cover the needs of total, partial and fine-tuning modulation of enzyme activity. These interactions comprise five linear and five hyperbolic inhibition mechanisms, five nonessential activation mechanisms and two hybrid species that manifest either hyperbolic inhibition or nonessential activation characteristics depending on substrate concentration. Five essential activation mechanisms, which are taxonomically independent of the mentioned basic species, complete the inventory of enzyme modifiers. Often masked under conventional umbrella terms or treated as anomalous cases, all seventeen basic inhibition and nonessential activation mechanisms are represented in the biochemical and pharmacological literature of this and the past century, either in the form of rapid or slow-onset reversible interactions, or as irreversible modification processes. The full potential of enzyme inhibitors and activators can only be appreciated after elucidating the details of their kinetic mechanisms of action exploring the entire range of physiologically significant reactant concentrations. This book highlights the wide spectrum of allosteric enzyme modification in physiological occurrences as well as in pharmacological and biotechnological applications that embrace simple and multiple enzyme-modifier interactions. The reader is guided in the journey through this still partly uncharted territory with the aid of mechanistically-oriented criteria aimed at showing the logical way towards the identification of a particular mechanism.
Reviews Of Physiology Biochemistry And Pharmacology
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-02
Reviews Of Physiology Biochemistry And Pharmacology written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-02 with Medical categories.
H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 - A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease.
Mathematical Modeling In Experimental Nutrition Vitamins Proteins Methods
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Author :
language : en
Publisher: Academic Press
Release Date : 1996-12-02
Mathematical Modeling In Experimental Nutrition Vitamins Proteins Methods written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-02 with Mathematics categories.
This book developed from a series of conferences to facilitate the application of mathematical modeling to experimental nutrition. As nutrition science moves from prevention of gross deficiencies to identifying requirements for optimum long term health, more sophisticated methods of nutritional assessment will be needed. Collection and evaluation of kinetic data may be one such method. This books opens with chapters giving specific examples of the application of modeling techniques to vitamin A, carotenoids, folate, vitamin b-6, glycogen phosphorylase, transthyretin, amino acids, and energy metabolism. Obtaining kinetic data on internal processes is a major challenge; therefore, the text includes chapters on the use of microdialysis and ultrafiltration, use of membrane vesicles, and culture of mammary tissue. Many of the authors use the Simulation, Analysis and Modeling program which allows compartmental models to be described without specifying the required differential equations. The final sections of the book, however, present some more mathematical descriptions of physiological processes, including bioperiodicity, metabolic control, and membrane transport; discussions of some computational aspects of modeling such as parameter distributions, linear integrators and identifiability; and alternative mathematical approaches such as neural networks and graph theory. Specific, detailed examples of applications of modeling to vitamins, proteins, amino acids, and energy metabolism Novel methods for collecting kinetic data--microdialysis, ultrafiltration, membrane vesicles, and the culture of mammary tissue Mathematical treatment of complex metabolic processes including bioperiodicity, metabolic control, and membrane transport Computational approaches to distribution of kinetic parameters, evaluation of linear integrators, and identifiability Alternative mathematical approaches--neural networks and graph theory Detailed descriptions of the application of modeling to a variety of nutrients
Biomolecular Kinetics
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Author : Clive R. Bagshaw
language : en
Publisher: CRC Press
Release Date : 2017-10-04
Biomolecular Kinetics written by Clive R. Bagshaw and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-04 with Medical categories.
"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.
Experimental Thermodynamics Volume X
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Author : Dick Bedeaux
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015-10-16
Experimental Thermodynamics Volume X written by Dick Bedeaux and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-16 with Science categories.
Covering recent developments in the theory of non-equilibrium thermodynamics and its applications, this title is aimed at a predominantly, but not exclusively, academic audience of practitioners of thermodynamics and energy conversion.