Free Radical Damage And Its Control
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Free Radical Damage And Its Control
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Author : C.A. Rice-Evans
language : en
Publisher: Elsevier
Release Date : 1994-02-09
Free Radical Damage And Its Control written by C.A. Rice-Evans and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-09 with Science categories.
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Free Radical Damage And Its Control
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Author : Catherine Rice-Evans
language : en
Publisher: Elsevier Science
Release Date : 1994-02-09
Free Radical Damage And Its Control written by Catherine Rice-Evans and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-09 with categories.
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth. The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Free Radical Damage And Its Control
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Author :
language : en
Publisher:
Release Date : 1994
Free Radical Damage And Its Control written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Active oxygen categories.
Phytochemicals
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Author : Toshiki Asao
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-11-07
Phytochemicals written by Toshiki Asao and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-07 with Science categories.
Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.
Oxidative Stress And Free Radical Damage In Neurology
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Author : Natan Gadoth
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-19
Oxidative Stress And Free Radical Damage In Neurology written by Natan Gadoth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-19 with Medical categories.
The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinson’s are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.
Antioxidants In Sport Nutrition
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Author : Manfred Lamprecht
language : en
Publisher: CRC Press
Release Date : 2014-09-17
Antioxidants In Sport Nutrition written by Manfred Lamprecht and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-17 with Medical categories.
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Free Radicals Oxidative Stress And Antioxidants
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Author : Tomris Özben
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Free Radicals Oxidative Stress And Antioxidants written by Tomris Özben and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.
Techniques In Free Radical Research
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Author : A.T. Diplock
language : en
Publisher: Elsevier
Release Date : 1991-12-11
Techniques In Free Radical Research written by A.T. Diplock and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-12-11 with Science categories.
Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage. Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.
Handbook Of Free Radicals
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Author : Dimitri Kozyrev
language : en
Publisher:
Release Date : 2010
Handbook Of Free Radicals written by Dimitri Kozyrev and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Free radicals categories.
Free radicals are molecules, ions, or atoms with unpaired electrons in their outermost shell of electrons. Although it is a relatively recent discovery, the occurrence of free radicals in biological processes is now widely accepted. Free radicals are involved in the pathogenesis of many diseases, such as diabetes, cardiovascular and pulmonary diseases and also in inflammation. Free radicals are also involved in important physiological processes, such as ageing. Free radicals are constantly formed in the human body, but they can become toxic when generated in excess or in the presence of a deficiency in the naturally occurring antioxidant defences. In general, the body has adequate antioxidant defences to cope with the production of free radicals under physiological conditions. This book reviews the updated knowledge on free radicals and its possible mechanisms in neurological disorders and in some oxidative stress processes, such as in intractable epilepsy and febrile seizures. Some approaches useful to elucidate the effects of free radical exposure on the overall protein structure are also discussed. Additionally, the potential risk factors and major cellular events contributing to the generation of reactive oxygen species and retinal pigment epithelium (EPI)/photoreceptor cell damage, and their roles in the pathogenesis of AMD are examined. Furthermore, thyroid cells are a unique model to study free radical processes involving reactive oxygen and iodine species. The role of oxidative stress in impairment in the thyroid function is explored. Other chapters in this book explore free radicals and its role in the in vivo disease control of malaria, as well as the monitoring of free radical in ultrasonic field in vitro and in vivo, its role in laboratory medicine, the relationship between rabies and free radicals, the correlation between exercise and free radical production, and the role of free radicals in several homeostatic processes through methods that can be used to detect free radicals either directly or indirectly (also known as fingerprinting methods).
Oxidative Stress And Antioxidant Protection
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Author : Donald Armstrong
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-11
Oxidative Stress And Antioxidant Protection written by Donald Armstrong and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-11 with Science categories.
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.