Free Radicals In Biology V4
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Free Radicals In Biology V4
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V4 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and the chemistry of the enzyme glutathione peroxidase. The next chapter is devoted to the kinetic aspects of lipid peroxidation and the multiple ways in which autoxidants can react. The reader is then introduced to the mechanisms of hepatoxicity by synthetic chemicals present in the environment, together with direct mechanisms of radiation damage to nucleic acids. Subsequent chapters deal with spin trapping in biological systems; the role of free radicals in arylamine carcinogenesis and their influence on the structure and reactivity of melanins; and the involvement of vitamin ? and lipid antioxidants in free-radical-initiated reactions. This book will be of value to chemists, biologists, and physicians.
Free Radicals In Biology
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Author : William A. Pryor
language : en
Publisher:
Release Date : 1976
Free Radicals In Biology written by William A. Pryor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Science categories.
Free Radicals in Biology V4 ...
Free Radicals In Biology And Medicine
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Author : Barry Halliwell
language : en
Publisher: OUP Oxford
Release Date : 2015-08-21
Free Radicals In Biology And Medicine written by Barry Halliwell and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Science categories.
Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
Oxygen Radicals In Biology And Medicine
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Author : Michael Simic
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Oxygen Radicals In Biology And Medicine written by Michael Simic and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.
Free Radicals In Biology V1
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V1 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume 1, provides an introduction to some of the basic concepts of free radical biology. The book emerged from the President's Symposium of the American Society for Experimental Pathology held in Atlantic City in April 1970. The book's opening chapter introduces a mechanistic view of free radical reactions using examples from biological systems. This is followed by a discussion of autoxidative damage to lipids in membranes. Some of the special chemistry of lipid oxidation are presented, and a number of novel ideas are suggested. The third chapter deals with the uses of electron-spin resonance in biology. Spin labeling is also discussed, which is one of the most useful methods of probing the chemical and physical environment of molecules in cells. The remaining chapters cover free radicals which occur in photosynthesis and the importance of the enzyme, superoxide dismutase. The study of the occurrence and reactions of this enzyme provides an important and extensive body of data clearly pointing to the significance of free radicals in cellular chemistry.
Free Radicals In Biology And Environment
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Author : F. Minisci
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Free Radicals In Biology And Environment written by F. Minisci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Our understanding of the quantitative aspects of free radical chemistry and the involvement of radicals in such areas as biology, medicine, the environment, etc., has developed spectacularly over recent years, yet the various topics are commonly discussed separately, in specific meetings and specialised publications. Free Radicals in Biology and Environment draws together two important areas of free radical chemistry, using as a bridge the fundamental physical chemistry of free radicals (spectroscopic detection of free radicals, evaluation of absolute rate constants, elucidation of mechanisms of free radical reactions and catalysis, photochemical and radiation processes, etc.). The most relevant topics covered are the EPR detection of radicals in biochemical systems and in pollutant formation and degradation, oxidation processes in biology and in the troposphere, radiation and induced damage, and atmospheric pollutants arising from incomplete combustion. Also covered are the chemistry and biochemistry of nitric oxide and peroxynitrite, the chemistry and biochemistry of DNA radicals, the role of radicals in myeloperoxidase, lignineperoxidase, radicals and cardiovascular injury, radiation and the fragmentation of cells and tissues.
Free Radical Medicine And Biology
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-15
Free Radical Medicine And Biology written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-15 with Science categories.
Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems.
Free Radicals In Biology V3
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Author : William Pryor
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Free Radicals In Biology V3 written by William Pryor and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Free Radicals in Biology, Volume III reviews diverse topics in free radical biology and relates the results of chemical and biochemical investigations to clinical situations. It attempts to bridge the gap between chemical investigations and the medical applications and implications of free radical reactions. Topics covered range from radiation chemistry to biochemistry, biology, and medicine. Comprised of seven chapters, this volume begins with a general introduction to the technique of radiation chemistry; the thermodynamics and kinetic factors that need be considered; the use of pulse radiolysis and flow techniques; and the application of these methods to free radicals of biological interest. The reader is then introduced to the pulse radiolysis method and the mechanisms of carbon tetrachloride toxicity. Subsequent chapters discuss the morphological, histochemical, biochemical, and chemical nature of lipofuscin pigments; production of free radicals from the reactions of selected enzymes with their substrates; and the damage caused to skin by sunlight. The final chapter deals with the involvement of free radicals in chemical carcinogenesis. This monograph will be of value to chemists, biologists, and physicians.
Oxidative Stress And Antioxidant Protection
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Author : Donald Armstrong
language : en
Publisher: John Wiley & Sons
Release Date : 2016-01-14
Oxidative Stress And Antioxidant Protection written by Donald Armstrong and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Science categories.
Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
Free Radicals And Oxidation Phenomena In Biological Systems
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Author : Roberfroid
language : en
Publisher: CRC Press
Release Date : 1994-12-14
Free Radicals And Oxidation Phenomena In Biological Systems written by Roberfroid and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-12-14 with Medical categories.
This work offers an analysis of the biological processes mediated by free radicals, from a toxicological point of view, providing easy access to information in an integrated, coherent presentation. The chemistry and biochemistry of all principal types of radical are explained, and the multiple forms in whch radicals participate in living organisms are investigated.;This work should be of use to biochemists, pharmacologists, pharmaceutical researchers, food scientists and technologists, nutritionists, toxicologists, chemists, biologists and graduate students in these disciplines.