Frontiers In The Actin Cytoskeleton
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Frontiers In The Actin Cytoskeleton
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Author : Francisco Rivero
language : en
Publisher: MDPI
Release Date : 2020-12-02
Frontiers In The Actin Cytoskeleton written by Francisco Rivero and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-02 with Science categories.
This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to the most complex animal cell. The actin cytoskeleton contributes to developing and maintaining cell shape and tissue integrity and is crucial for cell migration, movement of organelles, vesicle trafficking, and the completion of cell division. Elaborate structures like the sarcomere, the inner ear cell stereocilia, and the brush border microvilli are built on actin filament scaffolds. Dozens of actin-binding proteins orchestrate the dynamic remodeling of the actin cytoskeleton and integrate it with microtubules and intermediate filaments and with the cell signaling machinery. Playing such fundamental roles in a plethora of cellular processes, it comes as no surprise that defects in actin and associated proteins have been found to be implicated in pathological conditions as diverse as myopathies and neurodegenerative diseases. This Special Issue gathers 15 contributions highlighting the impressive advances made in recent years in this exciting field.
Frontiers In The Actin Cytoskeleton
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Author : Francisco Rivero
language : en
Publisher:
Release Date : 2020
Frontiers In The Actin Cytoskeleton written by Francisco Rivero and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to the most complex animal cell. The actin cytoskeleton contributes to developing and maintaining cell shape and tissue integrity and is crucial for cell migration, movement of organelles, vesicle trafficking, and the completion of cell division. Elaborate structures like the sarcomere, the inner ear cell stereocilia, and the brush border microvilli are built on actin filament scaffolds. Dozens of actin-binding proteins orchestrate the dynamic remodeling of the actin cytoskeleton and integrate it with microtubules and intermediate filaments and with the cell signaling machinery. Playing such fundamental roles in a plethora of cellular processes, it comes as no surprise that defects in actin and associated proteins have been found to be implicated in pathological conditions as diverse as myopathies and neurodegenerative diseases. This Special Issue gathers 15 contributions highlighting the impressive advances made in recent years in this exciting field.
International Journal Of Medical And Biological Frontiers
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Author :
language : en
Publisher:
Release Date : 2001
International Journal Of Medical And Biological Frontiers written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medicine categories.
Biomedical Engineering Frontier Research And Converging Technologies
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Author : Hanjoong Jo
language : en
Publisher: Springer
Release Date : 2015-07-23
Biomedical Engineering Frontier Research And Converging Technologies written by Hanjoong Jo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-23 with Technology & Engineering categories.
This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.
The Immunological Synapse Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-01-16
The Immunological Synapse Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-16 with Science categories.
The Immunological Synapse, Part A, Volume 173 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. Sections cover Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: control by polarity regulators, Analysis of centrosomal area actin reorganization and centrosome polarization upon lymphocyte activation at the immunological synapse, P815-based redirected degranulation assay to study human NK cell effector functions, Cytotoxic and Chemotactic Dynamics of Natural Killer Cells Quantified by Live-cell Imaging, Quantification of interaction frequency between antigen-presenting cells and T cells by conjugation assay, and more. Other chapters focus on the Study of the Effects of NK-Tumor Cell Interaction by Proteomic Analysis and Imaging, Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, An in vitro model to monitor natural killer cell effector functions against primary breast cancer, and Standardized Protocol for the Evaluation of Chimeric Antigen Receptor (CAR)-modified Cell Immunological Synapse Quality using the Glass-supported Planar L. - Covers various methods related to the study of the immunological synapse - Includes detailed, point-by-point, methods as well as various important notes - Provides the authority and expertise from an international board of leading scientists
Adsorption The New Frontier In Extracorporeal Blood Purification
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Author : Rinaldo Bellomo
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2023-08-07
Adsorption The New Frontier In Extracorporeal Blood Purification written by Rinaldo Bellomo and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-07 with Medical categories.
2023 is the time to collect available knowledge and basic concepts around extracorporeal blood purification in a book that may become the basis for expansion of awareness in the scientific community and a stimulus for new studies and new discoveries by scientists and investigators. We need to answer the question for hemoadsorption that we answered in the last four decades for hemodialysis and CRRT. The pathway towards the new frontier of hemoadsorption starts from this book.
Gpcrs
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Author : Beata Jastrzebska
language : en
Publisher: Academic Press
Release Date : 2019-09-11
Gpcrs written by Beata Jastrzebska and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-11 with Science categories.
GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer's disease, Parkinson's disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth. - Addresses our current understanding and novel advances in the GPCR field, directing readers towards recent finding of key significance for translational medicine - Combines a thorough discussion of structure and function of GPCRs with disease association and drug discovery - Features chapter contributions from international experts in GPCR structure, signaling, physiology and pharmacology
Frontiers Of Gastrointestinal Research
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Author : Leo Van der Reis
language : en
Publisher:
Release Date : 1995
Frontiers Of Gastrointestinal Research written by Leo Van der Reis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Digestive organs categories.
Frontiers Of Life
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Author : David Baltimore
language : en
Publisher:
Release Date : 2002
Frontiers Of Life written by David Baltimore and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Philosophy categories.
Comprehensive Frontier Of Kidney Disease In 2 Volumes
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Author : Shanyi Lin
language : en
Publisher: World Scientific
Release Date : 2024-10-11
Comprehensive Frontier Of Kidney Disease In 2 Volumes written by Shanyi Lin and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-11 with Medical categories.
In a world where kidney injury poses an ever-growing threat to human health due to aging populations and changing lifestyles, understanding and combating renal diseases have never been more critical.This book delves into cutting-edge renal disease research, where rapid developments have illuminated new technologies for diagnosis and treatment of the disease. The book systematically and comprehensively addresses clinical issues related to kidney diseases, where readers can explore topics such as hypoxia-inducible factors and renal anemia, pathogenesis of IgA nephropathy, hypertension, diabetic nephropathy, PLA2R antibodies and membranous nephropathy, immune nephropathy treatments using biological agents, renal glucose and energy metabolism, the application of SGLT2 inhibitors, and mechanisms of renal fibrosis.Written by over thirty experts who are actively shaping the field of nephrology in China and the USA, this book offers profound insights to understanding renal diseases, making it an indispensable resource for researchers, clinicians, and readers seeking to grow their knowledge on the scientific issues of kidney disease.