Functional Analysis And Fine Mapping Of A Neurodevelopmental Mutation In Zebrafish
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Functional Analysis And Fine Mapping Of A Neurodevelopmental Mutation In Zebrafish
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Author : Juli A. Armstrong
language : en
Publisher:
Release Date : 2004
Functional Analysis And Fine Mapping Of A Neurodevelopmental Mutation In Zebrafish written by Juli A. Armstrong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Zebra danio categories.
The World According To Zebrafish How Neural Circuits Generate Behaviour
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Author : Gonzalo G. De Polavieja
language : en
Publisher: Frontiers E-books
Release Date : 2014-11-07
The World According To Zebrafish How Neural Circuits Generate Behaviour written by Gonzalo G. De Polavieja and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-07 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.
Translational Toxicology
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Author : Claude L. Hughes
language : en
Publisher: Humana Press
Release Date : 2016-03-23
Translational Toxicology written by Claude L. Hughes and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-23 with Medical categories.
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.
The Zebrafish
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Author : Joseph A. Holden
language : en
Publisher: Cambridge University Press
Release Date : 2013-01-21
The Zebrafish written by Joseph A. Holden and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-21 with Science categories.
The zebrafish (Danio rerio) is a valuable and common model for researchers working in the fields of genetics, oncology and developmental sciences. This full-color atlas will aid experimental design and interpretation in these areas by providing a fundamental understanding of zebrafish anatomy. Over 150 photomicrographs are included and can be used for direct comparison with histological slides, allowing quick and accurate identification of the anatomic structures of interest. Hematoxylin and eosin stained longitudinal and transverse sections demonstrate gross anatomic relationships and illustrate the microscopic anatomy of major organs. Unlike much of the current literature, this book is focused exclusively on the zebrafish, eliminating the need for researchers to exclude structures that are only found in other fish.
Brain Development
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Author : Simon G Sprecher
language : en
Publisher: Humana
Release Date : 2013-09-19
Brain Development written by Simon G Sprecher and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-19 with Medical categories.
Providing widely used techniques in genetic model systems and many complementing animal models, Brain Development: Methods and Protocols focuses its expert contributions on two key technical aspects of developmental neurobiology: detection of gene expression and functional characterization of developmental control genes. Covering animal models such as the fruit fly, zebra fish, chicken, and mouse, this detailed book views in situ hybridization, reporter gene expression, and immunohistochemical staining methods, as well as RNA interference, Morpholino, or transgenic techniques through the prism of these models. Written in the highly successful Methods in Molecular Biology series format, chapter include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Brain Development: Methods and Protocols aims to provide precise technical protocols but also allows for comparing a wide range of protocols in different tissues and species.
Biology Of The Nmda Receptor
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Author : Antonius M. VanDongen
language : en
Publisher: CRC Press
Release Date : 2008-10-29
Biology Of The Nmda Receptor written by Antonius M. VanDongen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-29 with Medical categories.
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Diagnosis Management And Modeling Of Neurodevelopmental Disorders
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Author : Colin R. Martin
language : en
Publisher: Academic Press
Release Date : 2021-05-29
Diagnosis Management And Modeling Of Neurodevelopmental Disorders written by Colin R. Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-29 with Medical categories.
Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. In addition, the book also examines the pharmacological and non-pharmacological interventions of development-related conditions. Provides the most comprehensive coverage of the broad range of topics relating to the neuroscience of aging Features sections on the genetics that influences aging and diseases of aging Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables
Neurodevelopmental Disorders
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Author : Bin Chen
language : en
Publisher: Academic Press
Release Date : 2020-05-24
Neurodevelopmental Disorders written by Bin Chen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-24 with Medical categories.
Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development
Molecular And Genetic Mechanisms In Neurodevelopmental Disorders From Bench To Bedside
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Author : Rebecca Ann Muhle
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-02
Molecular And Genetic Mechanisms In Neurodevelopmental Disorders From Bench To Bedside written by Rebecca Ann Muhle and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-02 with Science categories.
Systems Biology Of Cancer
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Author : Sam Thiagalingam
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-09
Systems Biology Of Cancer written by Sam Thiagalingam and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-09 with Mathematics categories.
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.