Functional Genomics And Proteomics In The Clinical Neurosciences
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Functional Genomics And Proteomics In The Clinical Neurosciences
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Author : Scott E. Hemby
language : en
Publisher: Elsevier
Release Date : 2006-10-09
Functional Genomics And Proteomics In The Clinical Neurosciences written by Scott E. Hemby and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-09 with Science categories.
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses. * Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry* Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies* Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques
Functional Genomics And Proteomics In The Clinical Neurosciences
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Author : S. E. Hemby
language : en
Publisher:
Release Date : 2006
Functional Genomics And Proteomics In The Clinical Neurosciences written by S. E. Hemby and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Genomics categories.
Genomics Proteomics And The Nervous System
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Author : James D Clelland
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-03
Genomics Proteomics And The Nervous System written by James D Clelland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-03 with Medical categories.
This newest volume of Advances in Neurobiology discusses the utilization of genomic and proteomic technologies, to address facets of neurobiology including development and epigenetic regulation, functions in learning and memory, and changes associated with neurological and psychiatric disorders.
Functional Genomics And Proteomics In The Clinical Neurosciences
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Author : Scott E. Hemby
language : en
Publisher: Elsevier Science
Release Date : 2006-12-22
Functional Genomics And Proteomics In The Clinical Neurosciences written by Scott E. Hemby and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-22 with Science categories.
The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression. There are many potential applications for proteomics in neuroscience: determination of the neuro-proteome, comparative protein expression profiling, post-translational protein modification profiling and mapping protein-protein interactions, to name but a few. Functional Genomics and Proteomics in Clinical Neuroscience will comment on all of these applications, but with an emphasis on protein expression profiling. This book combines the basic methodology of genomics and proteomics with the current applications of such technologies in understanding psychiatric illnesses. * Introduction of basic methodologies in genomics and proteomics and their integration in psychiatry * Development of the text in sections related to methods, application and future directions of these rapidly advancing technologies * Use of actual data to illustrate many principles of functional genomics and proteomics. * Introduction to bioinformatics and database management techniques
Genomics Circuits And Pathways In Clinical Neuropsychiatry
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Author : Thomas Lehner
language : en
Publisher: Academic Press
Release Date : 2016-06-07
Genomics Circuits And Pathways In Clinical Neuropsychiatry written by Thomas Lehner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Science categories.
This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment
Neuroscience For Neurologists
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Author : Patrick F. Chinnery
language : en
Publisher: Imperial College Press
Release Date : 2006
Neuroscience For Neurologists written by Patrick F. Chinnery and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.
The last decade has seen major advances in our understanding of the basic scientific principles that underpin clinical neurology. Many of these advances have already had a major impact on routine clinical practice, and this is likely to continue in the future. Although this makes it an exciting time to practice neurology, it also presents new challenges. How can established general neurologists keep up-to-date with clinically relevant scientific advances, and how can the specialist remain competent outside his own field? What should trainee neurologists learn to prepare themselves for the future career?. Written by experts in the field, this timely book presents the scientific principles behind neurology. It aims to take the reader from the human genome, through gene expression, to molecular and cellular pathology, and subsequently to contemporary clinical investigations and clinical trials. Each contribution includes a discussion about the future of the field and highlights areas of potential growth and their relevance to routine clinical practice over the next decade. The succinctly written chapters will be easily accessible to both neurologists and trainees who have no expertise in the area. Many of the chapters are co-written by a clinician and a basic scientist, and each has been subject to peer review OCo both by experts in the field and a OC jobbingOCO general neurologist. This has ensured that the contributions reflect contemporary scientific thinking which is presented in a way that is easy to digest. The book includes generous use of diagrams to help explain difficult concepts, a glossary explaining the terminology, and provides information on links to web-based resources for further information. Sample Chapter(s). Chapter 1: Neurogenetics -- Single Gene Disorders (761 KB). Contents: Neurogenetics OCo Single Gene Disorders; Neurogenetics II: Complex Disorders; Functional Genomics and Proteomics: Application in Neurosciences; Mitochondria; Nanotechnology for Neuronal Ion Channels; Molecular and Cellular Pathways of Neurodegeneration in Motor Neurone Disease; Neurodegenerative Disorders: Parkinson''s Disease and Huntington''s Disease; Molecular Pathogenesis of Neuroinflammation; Neurovirology; Molecular Neurology of Prion Disease; Monitoring and Interpretation of Intracranial Pressure; Cerebral Perfusion and Stroke; A Review of Structural Magnetic Resonance Neuroimaging; Applications of Positron Emission Tomography (PET) in Neurology; Functional Magnetic Resonance Imaging; How to Spot Bias and Other Potential Problems in Randomised Controlled Trials. Readership: Neurologists, trainees/interns in neurology and related disciplines, neurobiologists."
Bioinformatics And Functional Genomics
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Author : Jonathan Pevsner
language : en
Publisher: John Wiley & Sons
Release Date : 2015-08-17
Bioinformatics And Functional Genomics written by Jonathan Pevsner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-17 with Science categories.
The bestselling introduction to bioinformatics and genomics – now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research. This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include: Extensive revisions and a slight reorder of chapters for a more effective organization A brand new chapter on next-generation sequencing An expanded companion website, also updated as and when new information becomes available Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics. Bioinformatics and Functional Genomics, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.
Genomics Proteomics And The Nervous System
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Author :
language : en
Publisher:
Release Date : 2011-04-11
Genomics Proteomics And The Nervous System written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-11 with categories.
Memories Molecules And Circuits
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Author : B. Bontempi
language : en
Publisher: Springer
Release Date : 2010-11-30
Memories Molecules And Circuits written by B. Bontempi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-30 with Medical categories.
This volume surveys the recent advances and provides an integrative view of molecular, cellular, and systems level mechanisms underlying cognitive processes in both animals and humans. Current and future avenues are discussed by distinguished scientists. They provide an overview of the underlying neurobiology of cognitive processes, and focus on clinical and therapeutic aspects surrounding impairments associated with disorders that affect cognition.
Cultural Neuroscience Cultural Influences On Brain Function
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Author : Juan Y. Chiao
language : en
Publisher: Elsevier
Release Date : 2009-11-25
Cultural Neuroscience Cultural Influences On Brain Function written by Juan Y. Chiao and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-25 with Science categories.
This volume presents recent empirical advances using neuroscience techniques to investigate how culture influences neural processes underlying a wide range of human abilities, from perception and scene processing to memory and social cognition. It also highlights the theoretical and methodological issues with conducting cultural neuroscience research. Section I provides diverse theoretical perspectives on how culture and biology interact are represented. Sections II –VI is to demonstrate how cultural values, beliefs, practices and experience affect neural systems underlying a wide range of human behavior from perception and cognition to emotion, social cognition and decision-making. The final section presents arguments for integrating the study of culture and the human brain by providing an explicit articulation of how the study of culture can inform the study of the brain and vice versa.