Functional Neural Transplantation Ii Novel Cell Therapies For Cns Disorders
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Functional Neural Transplantation Ii
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Author : Stephen B. Dunnett
language : en
Publisher:
Release Date : 2000
Functional Neural Transplantation Ii written by Stephen B. Dunnett and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Central nervous system categories.
Functional Neural Transplantation Ii Novel Cell Therapies For Cns Disorders
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Author : S.B. Dunnett
language : en
Publisher: Elsevier Science
Release Date : 2000-12-11
Functional Neural Transplantation Ii Novel Cell Therapies For Cns Disorders written by S.B. Dunnett and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-11 with Science categories.
The first edition of Functional Neural Transplantation, appearing in 1994, was commissioned to provide a systematic overview of the main areas of active research into the use of neural transplantation for functional repair at that time. There have though been major developments in the field over the last decade. First, whereas many of the model systems are the same, the sophistication of the research has developed dramatically. Secondly, there has been a major change in focus related to the nature of the optimal reparative process, moving away from a primary goal involving repair by replacement of lost cells, to strategies based on halting or reversing the disease process itself. Thirdly, the last decade has (not surprisingly) seen an expansion in the breadth of clinical applications for transplantation not only of primary embryonic neural tissues but also the initial applications of cells and cell lines. In order to address these recent developments as we enter the 21st century, 10 years after conception and 6 years after the publication of Functional Neural Transplantation, the Editors have now sought to co-ordinate and edit an updated version, Functional Neural Transplantation II. Functional Neural Transplantation II is not just a revised edition of the previous volume, but an entirely new and complementary second volume to update the field to 'state of the art' for the new millennium. For many major topic areas (such as functional repair in neurodegenerative disorders of the basal ganglia) there has been a continual flow of significant advances. Although these topics are covered in both volumes, the Editors have sought to avoid duplication by requiring that the present coverage emphasises the major developments over the last decade while relying on the first volume for the background overviews. Other topics though are entirely new in the present volume, such as novel applications of neural transplantation to other major clinical relevance such as retinal repair or alleviation of pain. A key departure of the present volume is the addition of several early chapters addressing the technical and developmental issues associated with identification of alternative sources of cells for transplantation - cell lines, immortalised cells, precursor/stem cells and xenotransplantation.
Functional Neural Transplantation Iii
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Author :
language : en
Publisher: Newnes
Release Date : 2012-12-31
Functional Neural Transplantation Iii written by and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Functional Neural Transplantation Iii
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Author :
language : en
Publisher: Elsevier
Release Date : 2012-12-26
Functional Neural Transplantation Iii written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Functional Neural Transplantation Iv
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-05-25
Functional Neural Transplantation Iv written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-25 with Medical categories.
Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides a survey of the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science to an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair. Selected chapters review the latest advances in translating the new technologies to a broader range of neurodegenerative diseases, stroke, spinal cord injury, glial and retinal disease and pain than had hitherto been considered possible, with the realization that the opportunities of off-the-shelf cell therapy may fast be approaching a plausible reality. Comprehensive set of critical reviews covering the field Presents state-of-the-art topics in science and translational medicine Written by international leaders in the field of neural transplantation
Functional Neural Transplantation Iii
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Author : Stephen B. Dunnett
language : en
Publisher:
Release Date : 2012
Functional Neural Transplantation Iii written by Stephen B. Dunnett and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Brain categories.
"This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery."--Publisher's website
Functional Neural Transplantation Iv
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-05-26
Functional Neural Transplantation Iv written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-26 with Medical categories.
Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodegenerative disease. New to this release are chapters that delve into the Mechanisms and Use of Neural Transplants for Brain Repair, Reprogramming of Somatic Cells: iPS and iN Cells, Brain Repair from Intrinsic Cell Sources: Turning Reactive Glia into Neurons, and Ex Vivo Gene Therapy for the Treatment of Neurological Disorders, Preparation, Characterization and Banking of Clinical-grade Cells for Neural Transplantation. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments related to the application of advances in cellular and molecular science, providing an understanding of the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the topic of the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.
Handbook Of Innovations In Central Nervous System Regenerative Medicine
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Author : António Salgado
language : en
Publisher: Elsevier
Release Date : 2020-06-10
Handbook Of Innovations In Central Nervous System Regenerative Medicine written by António Salgado and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-10 with Medical categories.
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Functional Neural Transplantation Iv
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-06-07
Functional Neural Transplantation Iv written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-07 with Medical categories.
Functional Neural Transplantation IV: Translation to Clinical Application, Part B, Volume 231 provides the current status of cell transplantation in the nervous system, focusing on the conditions for achieving structural repair and functional recovery after brain damage or disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments in cellular and molecular science, providing the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, and also addressing the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair. Selected chapters review the latest advances in translating new technologies to a broader range of neurodegenerative diseases, stroke, spinal cord injury, glial and retinal disease and pain than had hitherto been considered impossible, with a realization that the opportunities of off-the-shelf cell therapy may fast be approaching a plausible reality. Provides a comprehensive set of critical reviews covering the field Presents state-of-the-art topics in science and translational medicine Written by international leaders in the field of neural transplantation
Neural Stem Cells For Brain And Spinal Cord Repair
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Author : Tanja Zigova
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-11-05
Neural Stem Cells For Brain And Spinal Cord Repair written by Tanja Zigova and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-05 with Medical categories.
Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.