Functional Screening For Cancer Drug Discovery From Experimental Approaches To Data Integration
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Functional Screening For Cancer Drug Discovery From Experimental Approaches To Data Integration
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Author : Wenyu Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-28
Functional Screening For Cancer Drug Discovery From Experimental Approaches To Data Integration written by Wenyu Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-28 with Science categories.
Advances In Cancer Research
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Author :
language : en
Publisher: Elsevier
Release Date : 2011-07-29
Advances In Cancer Research written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-29 with Science categories.
The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development – Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.
Methods Of Cancer Diagnosis Therapy And Prognosis
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Author : M. A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-07
Methods Of Cancer Diagnosis Therapy And Prognosis written by M. A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-07 with Medical categories.
There are more than 100 types of cancers In Part II, head and neck cancer is d- affecting all parts of the human body. cussed. The global number of annual new More than 11 million people are diagnosed cases of this malignancy is ~500,000. These with cancer every year, and it is estimated malignancies include oral squamous cell that there will be 16 million new cases by carcinoma, salivary gland tumors, tons- the year 2020. In 2005, 7. 6 million peo- lar cancer, tongue cancer, nasopharyngeal ple died of cancer, that is, 13% of the 58 carcinoma, and retinoblastoma, which are million deaths worldwide. It is estimated detailed. In Part III, diagnosis, therapy, and that 9 million people will die from can- prognosis of thyroid carcinoma are d- cer worldwide in 2015 and 11. 4 million cussed. The global number of new cases of will die in 2030. More than 70% of all thyroid cancer is ~141,000, and the number cancer deaths occur in low and middle of worldwide thyroid mortalities is ~35,375. income countries. These statistics underlie The number of new cases of this cancer in the fact that cancer is the deadliest of all the United States is ~33,550. Molecular human diseases. The enormity of the glo- genetics of thyroid cancer, gene expr- bal healthcare costs as a result of cancer sion markers for diagnosis, papillary t- cannot be overemphasized.
Biotechnology Annual Review
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Author : M. Raafat El-Gewely
language : en
Publisher: Elsevier
Release Date : 2005-08-29
Biotechnology Annual Review written by M. Raafat El-Gewely and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-29 with Medical categories.
Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists' knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, vehicles for the production of biotechnology products and methods for their detection, separation and analysis - to topics that are focused on the role of biotechnology in the health sciences. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.
Multidisciplinary Research Area In Arts Science Commerce Volume 3
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Author : Chief Editor- Biplab Auddya, Editor- Nazia Qureshi, Dr. Ratnaprava Parija, Dr. R. Senthamizh Veena, Dr. C. Salma, Milinkumar Maru, Mr Romero D’Souza
language : en
Publisher: The Hill Publication
Release Date : 2025-06-25
Multidisciplinary Research Area In Arts Science Commerce Volume 3 written by Chief Editor- Biplab Auddya, Editor- Nazia Qureshi, Dr. Ratnaprava Parija, Dr. R. Senthamizh Veena, Dr. C. Salma, Milinkumar Maru, Mr Romero D’Souza and has been published by The Hill Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Antiques & Collectibles categories.
Epigenetic Approaches In Drug Discovery Development And Treatment
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Author : Shibashish Giri
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-07
Epigenetic Approaches In Drug Discovery Development And Treatment written by Shibashish Giri and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-07 with categories.
Establishment of a normal phenotype involves dynamic epigenetic regulation of gene expression that when affected contributes to human diseases. On a molecular level, epigenetic regulation is marked by specific covalent modifications (acetylation, methylation, phosphorylation, sumoylation, PARylation and ubiquitylation) of DNA and its associated histones. Studies also suggest the influence of such epigenetic modifications on non-coding RNA expression implicated in normal and diseased phenotypes. Epigenetic control of genetic expression is a reversible process essential for normal development and function of an organism. Alteration of epigenetic regulation leads to various disease forms such as cancer, diabetes, inflammation and neuropsychiatric disorders. Assessing these alterations provides a deeper insight into the changes induced in the genome, which is often informative for identifying disease subtypes or developing suitable treatments. Therefore, epigenetics proves to be a key area of clinical investigation in diagnosis, prognosis, and treatment of complex diseases. Genetic mutations, environmental stress, pathogens and drugs of abuse are some of the predominant factors that induce and impact changes on chromatin, which directly dictate a diseased phenotype. It is essential to consider the interaction between genetic and epigenetic factors to understand the molecular mechanisms of complex human diseases for safer and efficient drug development. Furthermore, genetic variation in absorption, distribution, metabolism, and excretion (ADME) genes is insufficient to account for interindividual variability of drug response. Therefore, current efforts aim to identify epigenetic components of ADME gene regulation, which include phase-I and phase-II enzymes, uptake transporters, efflux transporters and nuclear receptors involved in regulation of ADME genes. Monitoring circulatory epigenetic biomarkers in liquid biopsies (blood, saliva, urine, cerebrospinal fluid) of disease-associated and drug-associated epigenetic alterations may prove useful for decision support for routine clinical treatment and drug discovery. Hence, recent drug discovery efforts on targeting the epigenome, has emerged an area of interest with several new drugs being developed, tested and some already approved by the US Food and Drug Administration (FDA). These new insights into the complexities of epigenetic regulation are key contributors to our basic understanding of this process in human health and disease, which will provide scope for innovative drug therapies. It is of urgency to aid the present understanding of epigenomics driven diseased outcomes, with the expectation that further studies will identify early markers of disease and targets for therapeutics.
Multi Omic Data Integration In Oncology
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Author : Chiara Romualdi
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-03
Multi Omic Data Integration In Oncology written by Chiara Romualdi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-03 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Deep Learning In Medical Signal And Image Processing
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Author : Aamir, Muhammad
language : en
Publisher: IGI Global
Release Date : 2025-05-23
Deep Learning In Medical Signal And Image Processing written by Aamir, Muhammad and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-23 with Computers categories.
Deep learning is revolutionizing the analysis of medical signals and images, offering unprecedented advancements in diagnostic accuracy and efficiency. Techniques such as convolutional and recurrent neural networks are transforming the processing of radiological scans, ultrasound images, and ECG readings. By enabling more detailed and precise interpretations, deep learning enhances the ability of healthcare providers to make timely and informed decisions. These innovations are reshaping medical workflows, improving patient outcomes, and paving the way for a future of more reliable and efficient healthcare solutions. Deep Learning in Medical Signal and Image Processing offers a comprehensive examination of deep learning, specifically through convolutional neural networks (CNNs) and recurrent neural networks (RNNs), to medical data. It explores the application of AI in the analysis of medical signals and images. Covering topics such as diagnostic accuracy, enhanced decision-making, and data augmentation techniques, this book is an excellent resource for medical practitioners, clinicians, data scientists, AI researchers, healthcare professionals, engineers, professionals, researchers, scholars, academicians, and more.
Phenotypic Drug Discovery
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Author : Angelique Augustin
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-10
Phenotypic Drug Discovery written by Angelique Augustin and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-10 with Medical categories.
Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of novel medical entities. This book aims to equip researchers with a thought-provoking guide to the application and development of contemporary phenotypic drug discovery for clinical success.
Application Of Ai
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Author : Dr. Surender Kumar Yadav
language : en
Publisher: GEH Press
Release Date : 2024-11-11
Application Of Ai written by Dr. Surender Kumar Yadav and has been published by GEH Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-11 with Computers categories.
IoT stands for the Internet of Things. It refers to the network of physical objects or "things" embedded with sensors, software, and other technologies that enable them to connect and exchange data with other devices and systems over the internet. These objects can range from everyday items such as household appliances, wearable devices, and vehicles to industrial machines and infrastructure components.