Functional Tissue Engineering For Regenerative Medical Research And New Drug Development

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Functional Tissue Engineering For Regenerative Medical Research And New Drug Development
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Author : Junxi Wu
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-19
Functional Tissue Engineering For Regenerative Medical Research And New Drug Development written by Junxi Wu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-19 with Technology & Engineering categories.
The animal-based model remains the predominant research platform in biomedical and pharmaceutical research. Animal usage in the UK alone increased by 6% in 2021, with mice and rats accounting for just under 1 million experimental procedures. However, the mismatch between animal models and clinical reality (e.g. species barrier, age mismatch, populational diversity level) presents a major hurdle for clinical translation. Consequently, only ~10% of new drug candidates are eventually certified for clinical use, presenting a soaring research cost of $ 4-12 billion/new drug in recent years. This grand challenge stimulates the development of human tissue-engineered human models (e.g. organoids, microfluidic chips, and organ-on-a-chip systems) as potential solutions to replace animal models. Despite the rapid progress in this field, current tissue-engineered human models are still insufficient to recapitulate the complex morphology of target tissues, and consequently, inadequate to model realistic tissue function or generate transplantable tissue/organ.
Principles Of Regenerative Medicine
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Author : Anthony Atala
language : en
Publisher: Academic Press
Release Date : 2010-12-16
Principles Of Regenerative Medicine written by Anthony Atala and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-16 with Science categories.
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs
Bionanocomposites In Tissue Engineering And Regenerative Medicine
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Author : Shakeel Ahmed
language : en
Publisher: Elsevier
Release Date : 2021-06-09
Bionanocomposites In Tissue Engineering And Regenerative Medicine written by Shakeel Ahmed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-09 with Medical categories.
Bionanocomposites in Tissue Engineering and Regenerative Medicine explores novel uses of these in tissue engineering and regenerative medicine. This book offers an interdisplinary approach, combining chemical, biomedical engineering, materials science and pharmacological aspects of the characterization, synthesis and application of bionanocomposites. Chapters cover a broad selection of bionanocomposites including chitosan, alginate and more, which are utilized in tissue engineering, wound healing, bone repair, drug formulation, cancer therapy, drug delivery, cartilage regeneration and dental implants. Additional sections of Bionanocomposites in Tissue Engineering and Regenerative Medicine discuss, in detail, the safety aspects and circular economy of bionanocomposites - offering an insight into the commercial and industrial aspects of these important materials. Bionanocomposites in Tissue Engineering and Regenerative Medicine will prove a highly useful text for for those in the fields of biomedical engineering, chemistry, pharmaceutics and materials science, both in academia and industrial R&D groups. Each bionanocomposite type is covered individually, providing specific and detailed information for each material Covers a range of tissue engineering and regenerative medicine applications, from dental and bone engineering to cancer therapy Offers an integrated approach, with contributions from authors across a variety of related disciplines, including biomedical engineering, chemistry and materials science
Novel Biomaterials For Regenerative Medicine
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Author : Heung Jae Chun
language : en
Publisher: Springer
Release Date : 2018-10-24
Novel Biomaterials For Regenerative Medicine written by Heung Jae Chun and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-24 with Science categories.
This book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.
Regenerative Pharmacology
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Author : George J. Christ
language : en
Publisher: Cambridge University Press
Release Date : 2013-04-15
Regenerative Pharmacology written by George J. Christ and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-15 with Medical categories.
A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.
Advanced Therapies For Cardiac Regeneration
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Author : Valeria Chiono
language : en
Publisher: Frontiers Media SA
Release Date : 2021-04-13
Advanced Therapies For Cardiac Regeneration written by Valeria Chiono and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-13 with Science categories.
The Research Topic is organized in the framework of the project BIORECAR (grant number: 772168; http://www.biorecar.polito.it/index.html)
Stem Cell Biology And Tissue Engineering In Dental Sciences
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Author : Ajaykumar Vishwakarma
language : en
Publisher: Academic Press
Release Date : 2014-11-05
Stem Cell Biology And Tissue Engineering In Dental Sciences written by Ajaykumar Vishwakarma and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-05 with Technology & Engineering categories.
Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. - Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization - Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology - Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine - Print book is available and black and white, and the ebook is in full color
Health Technology Sourcebook 2nd Ed
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Author : James Chambers
language : en
Publisher: Infobase Holdings, Inc
Release Date : 2021-07-01
Health Technology Sourcebook 2nd Ed written by James Chambers and has been published by Infobase Holdings, Inc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-01 with Health & Fitness categories.
Consumer health information about the application of science to develop solutions to health problems or issues such as the prevention or delay of onset of diseases or the promotion and monitoring of good health. Includes index, glossary of related terms, and other resources.
Bionanocomposites In Tissue Engineering And Regenerative Medicine
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Author : Shakeel Ahmed
language : en
Publisher: Woodhead Publishing
Release Date : 2021-06-03
Bionanocomposites In Tissue Engineering And Regenerative Medicine written by Shakeel Ahmed and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-03 with Technology & Engineering categories.
Bionanocomposites in Tissue Engineering and Regenerative Medicine explores novel uses of these in tissue engineering and regenerative medicine. This book offers an interdisplinary approach, combining chemical, biomedical engineering, materials science and pharmacological aspects of the characterization, synthesis and application of bionanocomposites. Chapters cover a broad selection of bionanocomposites including chitosan, alginate and more, which are utilized in tissue engineering, wound healing, bone repair, drug formulation, cancer therapy, drug delivery, cartilage regeneration and dental implants. Additional sections of Bionanocomposites in Tissue Engineering and Regenerative Medicine discuss, in detail, the safety aspects and circular economy of bionanocomposites – offering an insight into the commercial and industrial aspects of these important materials. Bionanocomposites in Tissue Engineering and Regenerative Medicine will prove a highly useful text for for those in the fields of biomedical engineering, chemistry, pharmaceutics and materials science, both in academia and industrial R&D groups. - Each bionanocomposite type is covered individually, providing specific and detailed information for each material - Covers a range of tissue engineering and regenerative medicine applications, from dental and bone engineering to cancer therapy - Offers an integrated approach, with contributions from authors across a variety of related disciplines, including biomedical engineering, chemistry and materials science
Advances In Additive Manufacturing
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Author : Sandip Kunar
language : en
Publisher: John Wiley & Sons
Release Date : 2024-09-17
Advances In Additive Manufacturing written by Sandip Kunar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-17 with Technology & Engineering categories.
This volume focuses on the fundamentals of additive manufacturing and its components, explains why and what we do, outlines what is crucial to the user, offers details on important applications such as in the aerospace, automotive, or medical areas, and the difficult certification process. This book explores the advancements in additive manufacturing which produces solid, free-form, nearly net-shaped objects. This refers to items that are easy to use, out-of-the-box, and not bound by the design constraints of modern manufacturing techniques. AM expands the definition of 3D printing to encompass a variety of procedures that begin with a three-dimensional computer model, incorporate an AM production procedure, and result in a useful product. The AM process can be confusing due to the rapid rise of competing techniques for fabricating 3D parts. This volume provides a thorough review of the basic components and procedures involved in additive manufacturing. It outlines a road map for where to begin, what to study, how everything goes together, and how AM might enable ideas outside traditional processing to realize those ideas in AM. Furthermore, this book investigates the benefits of AM including affordable access to 3D solid modeling software. With this software, learning is achieved without having to invest in costly industrial equipment. AM encompasses a variety of techniques, including those that use high-intensity beams to fuse powder or wire, and hybrid techniques that combine additive and subtractive manufacturing techniques. AM-related processes have developed at breakneck speed, giving rise to a deluge of acronyms and terminology, not to mention the emergence, acquisition, and demise of new businesses. By combining ideas and aspirations, better methods will be revealed that result in useful products that will serve and contribute to a lasting future. Although expensive commercial additive manufacturing equipment can cost hundreds of thousands to millions of dollars, a lack of access to equipment does not preclude the study of the technology. 3D printing services will undoubtedly become more reasonable for small- and medium-sized organizations as their prices decline. Hybrid 3D plastic printing technologies and low-cost hobbyist 3D weld deposition systems are already in development which will make the best 3D printers accessible and affordable. This book will assist the reader in determining what is required to begin, which software, supplies, and procedures best suit, and where to obtain additional information. Audience The book will be used by engineers and R&D researchers involved in advanced additive manufacturing technology, postgraduate students in various disciplines such as mechanical, manufacturing, biomedical, and industrial engineering, etc. It will also serve as a reference manual for manufacturing and materials engineers involved in additive manufacturing and product development.