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Fundamentals Of Modern Bioprocessing


Fundamentals Of Modern Bioprocessing
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Fundamentals Of Modern Bioprocessing


Fundamentals Of Modern Bioprocessing
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2017-07-27

Fundamentals Of Modern Bioprocessing written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-27 with Medical categories.


Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.



Bioprocess Engineering For A Green Environment


Bioprocess Engineering For A Green Environment
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Author : V. Sivasubramanian
language : en
Publisher: CRC Press
Release Date : 2018-05-04

Bioprocess Engineering For A Green Environment written by V. Sivasubramanian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-04 with Medical categories.


Bioprocess Engineering for a Green Environment examines numerous bioprocesses that are crucial to our day-to-day life, specifically the major issues surrounding the production of energy relating to biofuels and waste management. The nuance of this discussion is reflected by the text’s chapter breakdown, providing the reader with a fulsome investigation of the energy sector; the importance of third-generation fuels; and the application of micro- and macroalgae for the production of biofuels. The book also provides a detailed exploration of biocatalysts and their application to the food industry; bioplastics production; conversion of agrowaste into polysaccharides; as well as the importance of biotechnology in bio-processing. Numerous industries discharge massive amounts of effluents into our rivers, seas, and air systems. As such, two chapters are dedicated to the treatment of various pollutants through biological operation with hopes of achieving a cleaner, greener, environment. This book represents the most comprehensive study of bioprocessing—and its various applications to the environment—available on the market today. It was furthermore written with various researchers in mind, ranging from undergraduate and graduate students looking to enhance their knowledge of the topics presented to scholars and engineers interested in the bioprocessing field, as well as members of industry and policy-makers. Provides a comprehensive overview of bioprocesses that apply to day-to-day living. Is learner-centered, providing detailed diagrams for easy understanding. Explores the importance of biocatalysts and their applications to the food industry, as well as bioplastics production. Examines the unique capabilities of bioprocess engineering and its ability to treat various pollutants. .



Handbook Of Preformulation


Handbook Of Preformulation
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2019-03-22

Handbook Of Preformulation written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with Medical categories.


Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this fully revised and updated Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second Edition provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity. Features: Addresses the preformulation studies of three different types of new active entities - chemical, biological, and botanical, which is the latest established class of active ingredient classified by the FDA Illustrates the activities comprised in preformulation studies and establishes a method of tasking for drug development projects Includes extensive flow charts for characterization decision making Gives extensive theoretical treatment of principles important for testing dissolution, solubility, stability, and solid state characterization Includes over 50% new material



Microbial Biotechnology


Microbial Biotechnology
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Author : Kay Yeoman
language : en
Publisher: Academic
Release Date : 2021

Microbial Biotechnology written by Kay Yeoman and has been published by Academic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.


La 4e de couverture indique : "In this title, a team of microbiologists explore how microbial biotechnology and its applications are fundamental to our way of life. They explain microbial growth and how this relates to food biotechnology as well as a number of othermicrobial products, from fine chemicals to pharmaceuticals, examine ethical and societal factors, and consider the future of microbial biotechnology in the context of advances being made in synthetic biology."



Disposable Bioprocessing Systems


Disposable Bioprocessing Systems
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Disposable Bioprocessing Systems written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


Written by a researcher with experience designing, establishing, and validating biological manufacturing facilities worldwide, this is the first comprehensive introduction to disposable systems for biological drug manufacturing. It reviews the current state of the industry; tackles questions about safety, costs, regulations, and waste disposal; and guides readers to choose disposable components that meet their needs. This practical manual covers disposable containers, mixing systems, bioreactors, connectors and transfers, controls and sensors, downstream processing systems, filling and finishing systems, and filters. The author also shares his predictions for the future, calling disposable bioprocessing technology a "game changer."



Bioprocessing For Value Added Products From Renewable Resources


Bioprocessing For Value Added Products From Renewable Resources
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Author : Shang-Tian Yang
language : en
Publisher: Elsevier
Release Date : 2011-08-11

Bioprocessing For Value Added Products From Renewable Resources written by Shang-Tian Yang and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-11 with Technology & Engineering categories.


Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry



Bioprocess Engineering Principles


Bioprocess Engineering Principles
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Author : Pauline M. Doran
language : en
Publisher: Elsevier
Release Date : 1995-04-03

Bioprocess Engineering Principles written by Pauline M. Doran and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-03 with Science categories.


The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.



Handbook Of Pharmaceutical Manufacturing Formulations Third Edition


Handbook Of Pharmaceutical Manufacturing Formulations Third Edition
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2019-12-09

Handbook Of Pharmaceutical Manufacturing Formulations Third Edition written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-09 with Medical categories.


The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Six, Sterile Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this sixth volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features: Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines



Biochemical Reaction Engineering


Biochemical Reaction Engineering
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Author : Kaustubha Mohanty
language : en
Publisher: CRC Press
Release Date : 2025-01-29

Biochemical Reaction Engineering written by Kaustubha Mohanty and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-29 with Technology & Engineering categories.


This textbook comprehensively covers fundamental and advanced aspects of biochemical engineering along with MATLAB codes. It comprehensively covers important topics including enzyme catalyzed reaction kinetics, catalytic antibodies and non-protein biomolecules as catalysts, process flow diagram (PFD), piping & instrumentation diagram (P&ID), wastewater treatment processes, design of fermenters and mass and energy balance. Pedagogical features including solved problems and unsolved exercises are interspersed throughout the text for better understanding. This book: Provides solid foundation and understanding of the fundamental principles of mathematics, science, and engineering Explores tools for solving theoretical and open-ended biochemical engineering problems Covers principles of downstream process and biochemical engineering principles with illustration and problems Discusses application of computer and programming in biochemical engineering Covers case studies for bioprocess plant design. The textbook is primarily written for senior undergraduate and graduate students in the fields of chemical engineering, biotechnology, and food process engineering for courses on biochemical engineering/bioprocess engineering/downstream processing.



Biosimilars And Interchangeable Biologics


Biosimilars And Interchangeable Biologics
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Author : Sarfaraz K. Niazi
language : en
Publisher: CRC Press
Release Date : 2018-10-30

Biosimilars And Interchangeable Biologics written by Sarfaraz K. Niazi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-30 with Medical categories.


What’s the Deal with Biosimilars? Biosimilars are gaining momentum as new protein therapeutic candidates that can help fill a vital need in the healthcare industry. The biological drugs are produced by recombinant DNA technology that allows for large-scale production and an overall reduction time in costs and development. Part of a two-volume set that covers varying aspects of biosimilars, Biosimilars and Interchangeable Biologics: Strategic Elements explores the strategic planning side of biosimilar drugs and targets issues surrounding biosimilars that are linked to legal matters. This includes principal patents and intellectual property, regulatory pathways, and concerns about affordability on a global scale. It addresses the complexity of biosimilar products, and it discusses the utilization of biosimilars and related biological drugs in expanding world markets. Of specific interest to practitioners, researchers, and scientists in the biopharmaceutical industry, this volume examines the science, technology, finance, legality, ethics, and politics of biosimilar drugs. It considers strategic planning elements that include an overall understanding of the history and the current status of the art and science of biosimilars, and it provides detailed descriptions of the legal, regulatory, and commercial characteristics. The book also presents a global strategy on how to build, take to market, and manage the next generation of biosimilars throughout their life cycle.