Fundamentals Of Molecular Structural Biology


Fundamentals Of Molecular Structural Biology
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Fundamentals Of Molecular Structural Biology


Fundamentals Of Molecular Structural Biology
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Author : Subrata Pal
language : en
Publisher: Academic Press
Release Date : 2019-08-13

Fundamentals Of Molecular Structural Biology written by Subrata Pal and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Science categories.


Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease



Foundations Of Structural Biology


Foundations Of Structural Biology
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Author : Leonard J. Banaszak
language : en
Publisher: Elsevier
Release Date : 2000-02-08

Foundations Of Structural Biology written by Leonard J. Banaszak and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-08 with Science categories.


Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features* Explains how to use coordinate databases and atomic coordinates of biological macromolecules* Teaches the skills of stereoviewing* Contains computer-generated stereographics* Describes the principles of symmetry and handedness in proteins and DNA* Introduces metal and lipid binding proteins and DNA-protein interactions* Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions



Structural Molecular Biology


Structural Molecular Biology
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Author : David Davies
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Structural Molecular Biology written by David Davies and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.


Structural biology is undergoing a revolution in both the sophistication of new biophysical methods and the complexity of problems in biomolecular structure and organization opened up for study. These changes are directly attributable to major advances in computer technology, computational methods, development of high intensity synchrotron radiation sources, new magnetic resonance methods, laser optical techniques, etc. Structure-function problems previously considered intractable may now be solved. As this area of specialisation continues to expand, there is a need to review the various physical methods currently being used and developed in struc tural molecular biology. At the same time that individual techniques and their applications become more specialized, the need for effect ive communication between investigators gains in imperative. It is vital to forge links among sub-disciplines and to emphasise the complementary nature of results observed by different biophysical methods. This publication contains the review lectures given at a meeting on "Current Methods in Structural Molecular Biology" spon sored by NATO as an Advanced Study Institute and by FEBS ~s Advanced Course No. 78. The aim of the meeting was to bring together, in a teaching environment, students and specialists in diverse biophysical methodologies with the specific purpose of exploring, questioning and critically assessing the present and future state of biological structure research. The scientific content of the interdisciplinary Study Institute centred around three interrelated aspects; biophysical methods and instrumentation, their application to biological structure problems, and derivation of structural information and insights.



Fundamentals Of Biochemistry


Fundamentals Of Biochemistry
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Author : Donald Voet
language : en
Publisher: John Wiley & Sons
Release Date : 2016-02-29

Fundamentals Of Biochemistry written by Donald Voet and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-29 with Science categories.


Voet, Voet and Pratt's Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. While continuing in its tradition of presenting complete and balanced coverage that is clearly written and relevant to human health and disease, Fundamentals of Biochemistry, 5e includes new pedagogy and enhanced visuals that provide a pathway for student learning.



Fundamentals Of Protein Nmr Spectroscopy


Fundamentals Of Protein Nmr Spectroscopy
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Author : Gordon S. Rule
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-10-28

Fundamentals Of Protein Nmr Spectroscopy written by Gordon S. Rule and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-28 with Science categories.


NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.



Essentials Of Molecular Biology


Essentials Of Molecular Biology
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Author : George M. Malacinski
language : en
Publisher:
Release Date : 2003

Essentials Of Molecular Biology written by George M. Malacinski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Molecular biology categories.


Focuses on the fundamental aspects of molecular structure and funciton by reviewing key features, and along the way, capsulizing them as a series of concise concepts. Users are encouraged to place the essential knowledge of molecular biology into broad contexts and develop both academic and personal meaning for this discipline.



Textbook Of Structural Biology


Textbook Of Structural Biology
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Author : Anders Liljas
language : en
Publisher: World Scientific
Release Date : 2009

Textbook Of Structural Biology written by Anders Liljas and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.


A textbook for undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine. It covers various aspects of proteins, nucleic acids and lipids, including the rise and fall of proteins, membranes and gradients, the structural biology of cells, and evolution - the comparative structural biology.



Protein Nucleic Acid Interactions


Protein Nucleic Acid Interactions
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Author : Phoebe A. Rice
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008-05-22

Protein Nucleic Acid Interactions written by Phoebe A. Rice and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-22 with Science categories.


This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.



Fundamentals Of Molecular Biology


Fundamentals Of Molecular Biology
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Author : Jayanta K. Pal
language : en
Publisher: Oxford University Press, USA
Release Date : 2009

Fundamentals Of Molecular Biology written by Jayanta K. Pal and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Fundamentals categories.


Fundamentals of Molecular Biology is designed to serve as a syllabus-oriented textbook for undergraduate students of Biotechnology from JNTU, Anna University, BITS Pilani, WBUT etc. The focus is on explaining the basic concepts and techniques in molecular biology and their applications thereof. Starting with the definition and role of molecular biology, the book provides complete coverage of topics such as micro and macromolecule, DNA enzymes, the concept of genomes and various techniques used through its study and an overview of recombinant DNA technology and its applications. The book delves deeper into the subject by providing discussions on DNA replication, its damage, repair and recombination, transcription machinery in prokaryotes and eukaryotes, translation, protein folding, modifications and degradations, finally concluding with a detailed discussion on Genomics and Proteomics. The book is written in simple language aimed at helping students assimilate complex theories with ease. The text is complemented by a large number of diagrams, colour illustrations, and end-chapter questions. Key terms are highlighted in the text for students to grasp concepts quickly. Exhaustive references for further reading are provided at the end of every chapter for the interested reader.



Molecular Biology Of Assemblies And Machines


Molecular Biology Of Assemblies And Machines
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Author : Alasdair Steven
language : en
Publisher: Garland Science
Release Date : 2016-02-18

Molecular Biology Of Assemblies And Machines written by Alasdair Steven and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-18 with Medical categories.


Molecular Biology of Assemblies and Machines provides a comprehensive narrative of the ways in which macromolecular structures assemble and how they interact with other complexes and organelles in the cell. Richly illustrated in full color, the text is written for advanced undergraduates, graduate students, and researchers in biochemistry, molecular biology, biophysics, cell biology, chemistry, structural biology, immunology, microbiology, and medicine.