Fundamentals Of Toxicologic Pathology
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Fundamentals Of Toxicologic Pathology
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Author : Matthew A. Wallig
language : en
Publisher: Academic Press
Release Date : 2009-11-23
Fundamentals Of Toxicologic Pathology written by Matthew A. Wallig and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-23 with Medical categories.
Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
Fundamentals Of Toxicologic Pathology
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Author : Matthew A. Wallig
language : en
Publisher: Academic Press
Release Date : 2017-10-25
Fundamentals Of Toxicologic Pathology written by Matthew A. Wallig and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-25 with Medical categories.
Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development. The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others. - Presents revised and updated information for each chapter on systems - Contains expanded sections on applied toxicologic pathology - Includes the essential information necessary to understand toxicologic pathology in an accessible language
Toxicologic Pathology For Non Pathologists
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Author : Thomas J. Steinbach
language : en
Publisher: Springer Nature
Release Date : 2019-10-31
Toxicologic Pathology For Non Pathologists written by Thomas J. Steinbach and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-31 with Medical categories.
This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.
Haschek And Rousseaux S Handbook Of Toxicologic Pathology
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Author : Wanda M Haschek
language : en
Publisher: Academic Press
Release Date : 2013-05-01
Haschek And Rousseaux S Handbook Of Toxicologic Pathology written by Wanda M Haschek and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-01 with Medical categories.
Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. - Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations
Fundamental Neuropathology For Pathologists And Toxicologists
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Author : Brad Bolon
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-08
Fundamental Neuropathology For Pathologists And Toxicologists written by Brad Bolon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-08 with Science categories.
This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 2 Safety Assessment And Toxicologic Pathology
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Author : Wanda M. Haschek
language : en
Publisher: Academic Press
Release Date : 2023-02-18
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 2 Safety Assessment And Toxicologic Pathology written by Wanda M. Haschek and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-18 with Medical categories.
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety. - Previous chapters on such topics as drug discovery and development, toxicity and carcinogenicity testing, report preparation, and risk assessment and communication have undergone extensive revision that includes in-depth discussion of new developments in the field - New chapters consider fundamental attributes for additional product classes including protein therapeutics, nucleic acid pharmaceutical agents, gene therapy and gene editing, stem cell and other cell therapies, vaccines, agricultural and bulk chemicals, and assigning adversity - Chapters dealing with product-specific practices address pathology and regulatory issues - Chapters offer high-quality and up-to-date content in a trusted work written by the collaborative efforts of many leading international subject matter experts - Hundreds of full-color images and diagrams are featured in both the print and electronic versions of this book to illustrate classic examples and highlight difficult concepts
Principles And Methods Of Toxicology Fifth Edition
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Author : A. Wallace Hayes
language : en
Publisher: CRC Press
Release Date : 2007-09-25
Principles And Methods Of Toxicology Fifth Edition written by A. Wallace Hayes and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-25 with Medical categories.
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.
Forensic Toxicology
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Author : Nicholas T. Lappas
language : en
Publisher: Academic Press
Release Date : 2015-11-14
Forensic Toxicology written by Nicholas T. Lappas and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-14 with Medical categories.
Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies. - Significant emphasis on the fundamental principles and concepts of forensic toxicology - Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field - Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases - The book's companion website, http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780127999678 features exclusive web-based content
Fundamentals Of Surgical Pathology
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Author : Shameem Shariff
language : en
Publisher: Jaypee Brothers Medical Publishers Pvt. Limited
Release Date : 2011-01-28
Fundamentals Of Surgical Pathology written by Shameem Shariff and has been published by Jaypee Brothers Medical Publishers Pvt. Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-28 with Medical categories.
This clear and concise reference book on surgical pathology is written for the pathologist who needs a well structured guide on specimen procedure and covers protocol for reporting results. It includes images of gross and microscopic pathology with correlating appearance of normal morphology and new sections providing points of differentiation between lesions with similar microscopic morphology. A section dedicated to Synoptic Histopathology Reporting and Minimum Data Sets outlines the responsibilities of a reporting pathologist in conveying to the clinician all relevant data for patient management.
A Primer Of Chemical Pathology
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Author : Evelyn S C Koay
language : en
Publisher: World Scientific Publishing Company
Release Date : 1996-02-09
A Primer Of Chemical Pathology written by Evelyn S C Koay and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-09 with Medical categories.
This book has been written primarily for medical students and junior doctors in clinical practice, but would also be a useful reference for postgraduate students in chemical pathology (clinical biochemistry), laboratory scientists, pathologists and medical laboratory technologists. It covers the field of chemical pathology, the biochemical basis of disease, and provides a basic understanding of the relationship between abnormal biochemical test results and disease states. A rational approach to proper selection and interpretation of biochemical investigations is adopted for each organ system or analyte covered in the 28 chapters. Emphasis is placed on areas and problems most commonly met with in clinical practice. Meant primarily as an introductory study book to the subject rather than as a reference text, the materials have been presented in a clear, condensed format to aid the study process. The written text is amply supplemented with relevant illustrations.