G Protein Signaling Mechanisms In The Retina
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G Protein Signaling Mechanisms In The Retina
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Author : Kirill A. Martemyanov
language : en
Publisher: Springer
Release Date : 2014-09-04
G Protein Signaling Mechanisms In The Retina written by Kirill A. Martemyanov and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-04 with Medical categories.
The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light. The organization of this volume will generally follow the path of signal flow in the retina. First we will describe recent advances in understanding the phototransduction cascade of rod and cone photoreceptors, which use signaling cascade based on the GPCR rhodopsin to transduce incident light into neural activity. Chapters will be devoted to unique specializations of the two major types of photosensitive cells that comprise the predominant input for our spatial and color vision. Subsequently, the mechanisms of synaptic information encoding by retinal ON bipolar cells will be described, where the GPCR mGluR6 plays a fundamental role. Chapters in this section will examine macromolecular organization of the mGluR6 signaling pathway as well as current understanding of its function. The functional characteristics of this signaling mechanism will be explored in detail. Additionally, this section will cover the role of dopamine receptors in modulating signal transmission between photoreceptors and ON-bipolar cells. Finally, chapters will be focused on the output neurons of the inner retina, ganglion cells, where the components of the emerging GPCR melanopsin cascade in intrinsically photosensitive ganglion cells will be detailed. Collectively these mechanisms allow the retina to represent visual space over a wide range of light intensities.
G Protein Signaling Mechanisms In The Retina
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Author : Kirill Martemyanov
language : en
Publisher:
Release Date : 2014-09-30
G Protein Signaling Mechanisms In The Retina written by Kirill Martemyanov and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-30 with categories.
Signal Transduction In The Retina
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Author : Steven J. Fliesler
language : en
Publisher: CRC Press
Release Date : 2007-12-26
Signal Transduction In The Retina written by Steven J. Fliesler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-26 with Science categories.
In the twenty-first century, we are just beginning to understand more clearly the enormous diversity and complexity of signaling processes in the retina. Integrating advances in the biochemistry, cell biology, physiology, and physics of phototransduction, Signal Transduction in the Retina presents the methodologies and experimental approaches that yield key information on the mechanisms underlying normal retinal physiology. This in-depth work discusses the latest techniques and applications for understanding retinal function and degradation, developing novel therapeutic strategies, and promoting cellular survival and functional retention. Drawing contributions from experts in a range of disciplines, each chapter presents a brief overview of the area discussed along with specific methodology for obtaining the primary data to understand the cellular and molecular process. Given the dominance and wealth of information on rhodopsin-based phototransduction, the book devotes substantial attention to this topic, but also evaluates a diversity of signaling mechanisms. Beginning with the molecular mechanisms of vertebrate phototransduction, this volume presents the structure of phototransduction cascade components at atomic resolution, as well as molecular interactions in multi-protein complexes and novel cell-based strategies for understanding signal shut-off and light adaptation. It discusses non-visual phototransduction and the role of melanopsin in adaptive photoresponses and circadian clock regulation. The book also compares the visual signaling processes of vertebrates and invertebrates. It examines experimental studies of insulin-based signaling in the inner and outer retina; investigates retinal development including signaling in progenitor cells, cell-cell communication in developing cells, and neovascularization; and studies lipid-derived mediators such as neuroprotectins and discusses the participation of retinal pigment epithelium in neuronal survival.
Signaling Mechanisms Regulating The Dual Function Transcription Factor Protein Phosphatase Eyes Absent During Drosophila Eye Development
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Author : Santiago Alejandro Morillo Salazar
language : en
Publisher:
Release Date : 2012
Signaling Mechanisms Regulating The Dual Function Transcription Factor Protein Phosphatase Eyes Absent During Drosophila Eye Development written by Santiago Alejandro Morillo Salazar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
In addition, I have contributed to a study examining the functions of the Abl kinase in patterning the Drosophila retina. Abl was previously identified as a regulator of Eya during photoreceptor morphogenesis, and here we show that Abl is also required for cell fate maintenance. Loss of Abl results in loss of neuronal markers in photoreceptor cells during late pupal stages and this correlates with upregulation of Notch signaling. Our results reveal developmental plasticity in photoreceptor cells and suggest a novel mechanism for terminal cell fate maintenance.
Webvision
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Author : Helga Kolb
language : en
Publisher:
Release Date : 2007
Webvision written by Helga Kolb and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Neuromorphic Olfaction
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Author : Krishna C. Persaud
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Neuromorphic Olfaction written by Krishna C. Persaud and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Principles Of Endocrinology And Hormone Action
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Author : Antonino Belfiore
language : en
Publisher: Springer
Release Date : 2018-02-08
Principles Of Endocrinology And Hormone Action written by Antonino Belfiore and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-08 with Medical categories.
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Signal Transduction Pathways Mechanisms And Diseases
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Author : Ari Sitaramayya
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-02
Signal Transduction Pathways Mechanisms And Diseases written by Ari Sitaramayya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Science categories.
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Ap Biology
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Author : Deborah T. Goldberg
language : en
Publisher: Simon and Schuster
Release Date : 2020-06-19
Ap Biology written by Deborah T. Goldberg and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-19 with Study Aids categories.
Be prepared for exam day with Barron’s. Trusted content from AP experts! Barron’s AP Biology: 2020-2021 includes in-depth content review and practice. It’s the only book you’ll need to be prepared for exam day. Written by Experienced Educators Learn from Barron’s--all content is written and reviewed by AP experts Build your understanding with comprehensive review tailored to the most recent exam Get a leg up with tips, strategies, and study advice for exam day--it’s like having a trusted tutor by your side Be Confident on Exam Day Sharpen your test-taking skills with 2 full-length practice tests Strengthen your knowledge with in-depth review covering all Units on the AP Biology Exam Reinforce your learning with practice questions at the end of each chapter