Signal Transduction Pathways Mechanisms And Diseases
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Signal Transduction Pathways Mechanisms And Diseases
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Author : Ari Sitaramayya
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-02
Signal Transduction Pathways Mechanisms And Diseases written by Ari Sitaramayya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-02 with Science categories.
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Regulation Of Signal Transduction In Human Cell Research
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Author : Nariyoshi Shinomiya
language : en
Publisher: Springer
Release Date : 2018-03-01
Regulation Of Signal Transduction In Human Cell Research written by Nariyoshi Shinomiya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-01 with Medical categories.
This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.
Heat Shock Proteins In Signaling Pathways
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Author : Alexzander A. A. Asea
language : en
Publisher:
Release Date : 2019
Heat Shock Proteins In Signaling Pathways written by Alexzander A. A. Asea and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biochemistry categories.
This edited volume offers an insightful overview of contemporary research on signaling pathways. These signaling processes are the comprehensive mechanisms by which all cellular organisms communicate internally and externally with their microenvironment. The volume is focused on heat shock proteins (HSP), which are uniquely involved in a number of critical signaling pathways. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. The knowledge gained from better understanding these mechanisms can help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
International Textbook Of Diabetes Mellitus
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Author : R. A. DeFronzo
language : en
Publisher: John Wiley & Sons
Release Date : 2015-03-11
International Textbook Of Diabetes Mellitus written by R. A. DeFronzo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-11 with Medical categories.
The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.
Microrna In Regenerative Medicine
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Author : Chandan K. Sen
language : en
Publisher: Academic Press
Release Date : 2023-05-08
Microrna In Regenerative Medicine written by Chandan K. Sen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-08 with Science categories.
Regulating virtually all biological processes, the genome's 2,654 newly discovered variants of mature microRNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body's toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In MicroRNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of miRNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, miRNA as biomarkers, microRNA in pregnancy and embryo development, exogenous and diet derived microRNA in tissue development, ocular microRNA, mitochondrial microRNA, sensory hair cell death and regeneration, and microRNA in senescence. - Features chapter contributions from international leaders in the field, covering the spectrum from bench to bedside - Includes short, applied chapters offering focused discussion and practical examples - Incorporates multi-color text layout with more than 150 color figures to illustrate important findings
Essentials Of Plant Anatomy
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Author : Ameyatma Mahajan
language : en
Publisher: Educohack Press
Release Date : 2025-02-20
Essentials Of Plant Anatomy written by Ameyatma Mahajan and has been published by Educohack Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-20 with Science categories.
"Essentials of Plant Anatomy" is a comprehensive guide to understanding the intricate structure and organization of plant tissues and organs. This book delves into the fundamental principles of plant anatomy, exploring diverse cell types, tissue systems, and anatomical adaptations that enable plants to grow, develop, and thrive in various environments. We embark on a journey through the microscopic world of plant cells, learning about the specialized functions and interactions of different cell types within tissues such as epidermis, parenchyma, collenchyma, and sclerenchyma. The book illuminates the role of these tissues in supporting plant growth, providing structural support, storing nutrients, and facilitating essential metabolic processes like photosynthesis and gas exchange. Furthermore, we delve into the complex organization of plant organs such as roots, stems, leaves, and flowers, unraveling anatomical adaptations that enable plants to absorb water and nutrients from the soil, transport fluids and nutrients throughout the plant, and engage in reproductive processes like pollination and seed dispersal. Through detailed illustrations, diagrams, and explanatory text, "Essentials of Plant Anatomy" provides readers with a deeper understanding of the developmental processes that shape plant morphology and anatomy, from meristematic tissue activity to the formation of specialized structures such as stomata, trichomes, and vascular bundles. This book serves as an invaluable resource for students, educators, researchers, and plant enthusiasts seeking to deepen their knowledge of plant structure and function. Whether used as a textbook for academic courses or as a reference guide for botanical research, it offers a rich and insightful exploration of the fascinating world of plant anatomy.
Targeting Signalling Pathways In Inflammatory Diseases
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Author : Uzma Saqib
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-14
Targeting Signalling Pathways In Inflammatory Diseases written by Uzma Saqib and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-14 with Medical categories.
Biochemistry Of Signal Transduction And Regulation
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Author : Gerhard Krauss
language : de
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Biochemistry Of Signal Transduction And Regulation written by Gerhard Krauss and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)
Structure And Function In Cell Signalling
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Author : John Nelson
language : en
Publisher: John Wiley & Sons
Release Date : 2008-08-06
Structure And Function In Cell Signalling written by John Nelson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-06 with Science categories.
"This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions ... the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009 "A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information." –Australian Biochemist, August 2009 "From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." –Doody's, January 2009 This text is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities – the ‘nuts and bolts’ of cellular information exchange. With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding. An accessible introduction to the complex field of cell signalling Interacts with RasMol software – freely downloadable for viewing structures in 3D Includes exercises and clear instructions in the use of RasMol Well illustrated in full colour throughout Structure and Function in Cell Signalling is an invaluable resource to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book provides a clear, accessible introduction to this rapidly expanding field.
Smad Signal Transduction
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Author : Peter Dijke
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-10
Smad Signal Transduction written by Peter Dijke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-10 with Science categories.
For the first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue homeostasis. In a series of 22 cutting-edge chapters forward looking reviews of Smads are provided that cover their discovery, evolution, role in development, mechanism of action and regulation, and how deregulation in Smad signalling contributes to human diseases. Written for an audience with basic understanding of molecular and cell biology, this volume provides an in-depth review of a rapidly developing field and extensive cross-references between chapters are provided. This book will be of particular interest to basic and applied biomedical researchers (students, post-docs or group leaders) with desire to understand the principles of cell-cell communication and mechanisms by which signaling pathways and gene programs control cell proliferation and differentiation, and how this knowledge may come to be applied in the clinic.