Gain Of Function Research
DOWNLOAD
Download Gain Of Function Research PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Gain Of Function Research book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Potential Risks And Benefits Of Gain Of Function Research
DOWNLOAD
Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2015-04-13
Potential Risks And Benefits Of Gain Of Function Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-13 with Science categories.
On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.
Biotechnology Research In An Age Of Terrorism
DOWNLOAD
Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2004-03-02
Biotechnology Research In An Age Of Terrorism written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-02 with Technology & Engineering categories.
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
What Really Happened In Wuhan
DOWNLOAD
Author : Sharri Markson
language : en
Publisher: HarperCollins
Release Date : 2021-10-01
What Really Happened In Wuhan written by Sharri Markson and has been published by HarperCollins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-01 with Health & Fitness categories.
Walkley Award-winning journalist, Sharri Markson is the Investigations Editor at The Australian and host of prime-time show Sharri on Sky News Australia. The origins of Covid-19 are shrouded in mystery. Scientists and government officials insisted, for a year and a half, that the virus had a natural origin, ridiculing anyone who dared contradict this view. Tech giants swept the internet, censoring and silencing debate in the most extreme fashion. Yet it is undeniable that a secretive facility in Wuhan was immersed in genetically manipulating bat-coronaviruses in perilous experiments. And as soon as the news of an outbreak in Wuhan leaked, the Chinese military took control and gagged all laboratory insiders. Part-thriller, part-expose, What Really Happened in Wuhan is a ground-breaking investigation from leading journalist Sharri Markson into the origins of Covid-19, the cover-ups, the conspiracies and the classified research. It features never-before-seen primary documents exposing China's concealment of the virus, fresh interviews with whistleblower doctors in Wuhan and crucial eyewitness accounts that dismantle what we thought we knew about when the outbreak hit. With unprecedented access to Washington insiders, Markson takes you inside the White House, with senior Trump lieutenants revealing first-hand accounts of fiery Oval Office clashes and new stories of compromised government advisors and censored scientists. Bravely reported and chillingly laid out, Markson brings to light the stories of the pandemic from the people on the ground: the scientists and national security officials who raised uncomfortable truths and were labelled conspiracy theorists, until government agencies began to suspect they might have been right all along. These brave individuals persisted through bruising battles and played a crucial role in investigating the origins of Covid-19 to finally, in this book, bring us closer to the truth of what really happened in Wuhan.
Dual Use Research Of Concern In The Life Sciences
DOWNLOAD
Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2017-10-01
Dual Use Research Of Concern In The Life Sciences written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-01 with Science categories.
The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
Viral
DOWNLOAD
Author : Matt Ridley
language : en
Publisher: HarperCollins
Release Date : 2022-06-28
Viral written by Matt Ridley and has been published by HarperCollins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-28 with Medical categories.
"Chan and Ridley write with an urgency...that inspires gripping depictions of what viruses are, how infectious-disease laboratories work and wonderfully lucid descriptions of bats. . . . They powerfully recount how dangerous pathogens can both leak from a lab and emerge in nature." (New York Times Book Review) Understanding how Covid-19 started is crucial for the future of humankind. Viral is the most incisive and authoritative book about the search for the source of the virus. A new virus descended on the human species in 2019 wreaking unprecedented havoc. Finding out where it came from and how it first jumped into people is an urgent priority, but early expectations that this would prove an easy question to answer have been dashed. Nearly two years into the pandemic, the crucial mystery of the origin of SARS-CoV-2 is not only unresolved but has deepened. In this uniquely insightful book, a scientist and a writer join forces to try to get to the bottom of how a virus whose closest relations live in bats in subtropical southern China somehow managed to begin spreading among people more than 1,500 kilometres away in the city of Wuhan. They grapple with the baffling fact that the virus left none of the expected traces that such outbreaks usually create: no infected market animals or wildlife, no chains of early cases in travellers to the city, no smouldering epidemic in a rural area, no rapid adaptation of the virus to its new host—human beings. To try to solve this pressing mystery, Viral delves deep into the events of 2019 leading up to 2021, the details of what went on in animal markets and virology laboratories, the records and data hidden from sight within archived Chinese theses and websites, and the clues that can be coaxed from the very text of the virus’s own genetic code. The result is a gripping detective story that takes the reader deeper and deeper into a metaphorical cave of mystery. One by one the authors explore promising tunnels only to show that they are blind alleys, until, miles beneath the surface, they find themselves tantalisingly close to a shaft that leads to the light.
Flu Hunter
DOWNLOAD
Author : Robert G. Webster
language : en
Publisher:
Release Date : 2018
Flu Hunter written by Robert G. Webster and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Avian influenza categories.
When a new influenza virus emerges that is able to be transmitted between humans, it spreads globally as a pandemic, often with high mortality. Enormous social disruption and substantial economic cost can result. The 1918 Spanish influenza pandemic was undoubtedly the most devastating influenza pandemic to date, and it has been Dr Robert Websters lifes work to figure out how and why. In so doing he has made a remarkable contribution to our understanding of the evolution of influenza viruses and how to control them. A century on, Flu Hunter is a gripping account of the tenacious scientific detective work involved in revealing the secrets of this killer virus. Dubbed Flu Hunter by Smithsonian Magazine in 2006, Dr Webster began his research in the early 1960s with the insight that the natural ecology of most influenza viruses is among wild aquatic birds. Painstaking tracking and testing of thousands of birds eventually led him and the other scientists involved to establish a link between these bird virus reservoirs and human influenza pandemics. Some of this fascinating scientific work involved exhuming bodies of Spanish flu victims from the Arctic permafrost in a search for tissue samples containing genetic material from the virus. Could a global influenza pandemic occur again? Websters warning is clear: "... it is not only possible, it is just a matter of when."
Gain Of Function Research
DOWNLOAD
Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-06-20
Gain Of Function Research written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-20 with Medical categories.
On March 10-11, 2016, the National Academies of Sciences, Engineering, and Medicine held a public symposium on potential U.S. government policies for the oversight of gain-of- function (GOF) research. This was the Academies' second meeting held at the request of the U.S. government to provide a mechanism to engage the life sciences community and the broader public and solicit feedback on optimal approaches to ensure effective federal oversight of GOF research as part of a broader U.S. government deliberative process. The first symposium, held in December 2014, examined the underlying scientific and technical questions surrounding the potential risks and benefits of GOF research involving pathogens with pandemic potential. The second symposium focused on discussion of the draft recommendations regarding GOF research of a Working Group of the National Science Advisory Board for Biosecurity. This report summarizes the key issues and ideas identified during the second symposium.
A Framework For K 12 Science Education
DOWNLOAD
Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-02-28
A Framework For K 12 Science Education written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-28 with Education categories.
Science, engineering, and technology permeate nearly every facet of modern life and hold the key to solving many of humanity's most pressing current and future challenges. The United States' position in the global economy is declining, in part because U.S. workers lack fundamental knowledge in these fields. To address the critical issues of U.S. competitiveness and to better prepare the workforce, A Framework for K-12 Science Education proposes a new approach to K-12 science education that will capture students' interest and provide them with the necessary foundational knowledge in the field. A Framework for K-12 Science Education outlines a broad set of expectations for students in science and engineering in grades K-12. These expectations will inform the development of new standards for K-12 science education and, subsequently, revisions to curriculum, instruction, assessment, and professional development for educators. This book identifies three dimensions that convey the core ideas and practices around which science and engineering education in these grades should be built. These three dimensions are: crosscutting concepts that unify the study of science through their common application across science and engineering; scientific and engineering practices; and disciplinary core ideas in the physical sciences, life sciences, and earth and space sciences and for engineering, technology, and the applications of science. The overarching goal is for all high school graduates to have sufficient knowledge of science and engineering to engage in public discussions on science-related issues, be careful consumers of scientific and technical information, and enter the careers of their choice. A Framework for K-12 Science Education is the first step in a process that can inform state-level decisions and achieve a research-grounded basis for improving science instruction and learning across the country. The book will guide standards developers, teachers, curriculum designers, assessment developers, state and district science administrators, and educators who teach science in informal environments.
Is Covid 19 A Bioweapon
DOWNLOAD
Author : Richard M. Fleming
language : en
Publisher: Simon and Schuster
Release Date : 2021-09-07
Is Covid 19 A Bioweapon written by Richard M. Fleming and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-07 with Health & Fitness categories.
What is the true origin of COVID-19? President Joe Biden has ordered US intelligence agencies to further investigate the origins of COVID-19. Clearly, the US government isn't decided on what really happened at the start of the pandemic. Was it truly a animal to human transmission to be blamed on a bat in a Wuhan, China wet market? Or was a much more sinister plan at work? In 2020, Dr. Richard M. Fleming began investigating SARS-CoV-2/COVID-19. Using both his "Inflammation" Theory and Patent (FMTVDM; the first method capable of measuring regional blood flow and metabolic changes occurring inside the body, which makes it possible to accurately determine what is happening inside the body as well as whether treatments prescribed for patients are working or not), he investigated COVID treatments. Simultaneously he began investigating the origins of COVID-19. This book details much of what he has found. What he discovered will shock you. By 1999, US Federal Agencies began funding Gain-of-Function research. Research that by its very nature is designed to increase the ability of pathogens to infect and harm people. In 2019, one of those pathogens was intentionally released upon the world in the Wuhan Wet Market. The key to proving and understanding this bioweapon is its spike protein. The very same spike protein now being made in millions of people after the COVID vaccines are injected into them. These vaccines are nothing more than the genetic code of this bioweapon. This book traces the publication and money trail of COVID-19; showing who is ultimately criminally responsible for the design and development of this weapon, which violates the Biological Weapons Convention (BWC) Treaty, exposing those who have committed crimes against humanity. Dr. Fleming will reveal the ultimate conspiracy: one that puts the future of the entire world at stake.
Influenza Virus
DOWNLOAD
Author : Yohei Yamauchi
language : en
Publisher: Humana Press
Release Date : 2018-08-28
Influenza Virus written by Yohei Yamauchi and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-28 with Medical categories.
This book provides researchers with widely used techniques for the study of virology, focusing on molecular biology and imaging to encourage mechanistic investigation of virus-host interactions. Chapters detail a broad range of methods from diagnosis, virus propagation, proteomics, haploid screening, lentiviral screening, virus entry, single molecule RNA imaging, correlative light and electron microscopy (CLEM), EM, light-sheet microscopy, biochemistry, viral transcription, physiological infection models, animal models, in vivo imaging, antigenic evolution, immunology to mathematical modelling. Reviews cover general influenza, clinical trials, both sides of the gain-of-function debate, and computational modelling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Influenza Virus: Methods and Protocols aims to motivate experienced researchers and newcomers in the field and improve our overall understanding of influenza.