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Gene And Immunotherapy For Hematological Diseases


Gene And Immunotherapy For Hematological Diseases
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Gene And Immunotherapy For Hematological Diseases


Gene And Immunotherapy For Hematological Diseases
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Author : Dagmar Dilloo
language : en
Publisher: S Karger Ag
Release Date : 2003-01-01

Gene And Immunotherapy For Hematological Diseases written by Dagmar Dilloo and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-01 with Medical categories.




Gene Based Therapies For Pediatric Blood Diseases An Issue Of Hematology Oncology Clinics Of North America E Book


Gene Based Therapies For Pediatric Blood Diseases An Issue Of Hematology Oncology Clinics Of North America E Book
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Author : Nirali N. Shah
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-07-19

Gene Based Therapies For Pediatric Blood Diseases An Issue Of Hematology Oncology Clinics Of North America E Book written by Nirali N. Shah and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-19 with Medical categories.


In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.



Blood Cell Biochemistry


Blood Cell Biochemistry
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Author : Leslie J. Fairbairn
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-03-31

Blood Cell Biochemistry written by Leslie J. Fairbairn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-03-31 with Medical categories.


This volume, the last in the excellent Blood Cell Biochemistry series, focuses specifically on gene therapy in the hematopoietic system; its applications, aspirations and problems, and provides insight as to how the hematopoietic system may be considered as a target in therapy of acquired and inherited disease of other tissues.



Cell Therapy


Cell Therapy
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Author : George Morstyn
language : en
Publisher: Cambridge University Press
Release Date : 1996-03-29

Cell Therapy written by George Morstyn and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-03-29 with Medical categories.


Cell therapy is a rapidly developing area, drawing on cell biology, molecular biology, virology, immunology, cell quantitation techniques and biomedical engineering. It has potential in many clinical settings, in the treatment of cancer and other diseases. This volume in the series Cancer: Clinical Science in Practice examines the current state and future prospects of cell therapy, which seems likely to have an even more profound impact on health care than did the production of proteins by recombinant DNA technology. The coverage is broad, including the scientific principles of haematopoietic cell therapy, the technology of cell collection and preparation, current and likely future clinical applications of cell therapy, and the principles and practice of cellular immunotherapy. Up-to-date and authoritative, volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.



Hematology


Hematology
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Author : Ronald Hoffman
language : en
Publisher: Elsevier Health Sciences
Release Date : 2022-10-27

Hematology written by Ronald Hoffman and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-27 with Medical categories.


Extensively revised, comprehensive content from leading global contributors ensures that Hematology, 8th Edition, remains your #1 choice for expert guidance in all areas of this rapidly advancing subspecialty. This edition reflects the numerous advances that are redefining the field and dramatically influencing new approaches to diagnosis, treatment, and outcomes. Well-illustrated and clinically focused, it details the basic science and clinical practice of hematology and hematopoietic cellular therapy—covering virtually all aspects of hematology in one definitive resource. Covers all hematologic disorders, including comprehensive discussions of hematologic malignancies, individualized patient care, cell-based therapies, transplantation, transfusion medicine, hemostasis, thrombosis, and consultative hematology—in one convenient volume. Provides state-of-the-art guidance from global experts at the forefront of the latest research and clinical practice. Provides extensive updates throughout on basic science research, advances in molecular diagnostics, new drugs, immunotherapies, personalized medicine, laboratory medicine, transfusion medicine, stem cell transplantation, and clinical treatment for all hematologic malignancies and non-malignancies Contains new chapters on gene editing; the impact of mitochondria on hematopoiesis; myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes; immunotherapy and management of its toxicities; transfusion medicine in sickle cell disease; principles of radiation therapy; and COVID-19, including complications of vaccination and its impact on the hematologic system. Discusses many new advances in the field, including details and the future of gene therapy for hemophilia, gene editing for sickle cell disease and thalassemia, the evolution of cellular therapy, use of cells, transfusion medicine vs. protein therapy, gene sequencing, immunotherapy, and new targeted drugs. Includes more decision-making algorithms for formulating diagnoses and personalized treatment plans for those highly complex disorders that require individualized approaches. Addresses the effects of aging on hematopoiesis and on the manifestations of a variety of hematologic disorders. Discusses cardio-oncology and its impact on the treatment of patients with hematologic disorders. Presents relevant basic science as background for clinical application in later sections.



Transplantation In Hematology And Oncology


Transplantation In Hematology And Oncology
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Author : T. Büchner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Transplantation In Hematology And Oncology written by T. Büchner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Some three decades after bone marrow transplantation was introduced in the field of hematology and oncology, transplantation today continues to rapidly grow and expand into a variety of new modalities. Peripheral blood has been established as an effective source of autologous progenitor cells. Furthermore, the graft-versus-leukemia effect has resulted in novel strategies of adoptive immunotherapy for cancer. Finally, approaches to gene transfer and therapy are utilizing transplantation methodologies and can augment their effects. Current results, new developments and perspectives are presented in this volume. Conventional and innovative experimental approaches, the past and the future of bone marrow transplantation are reviewed and discussed by leading representatives.



Genetic Variants As Targets For Immunotherapy Of Hematological Tumors


Genetic Variants As Targets For Immunotherapy Of Hematological Tumors
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Author : Marieke Griffioen
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-15

Genetic Variants As Targets For Immunotherapy Of Hematological Tumors written by Marieke Griffioen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-15 with Medical categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Gene Technology


Gene Technology
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Author : Axel R. Zander
language : en
Publisher: Springer
Release Date : 2011-10-28

Gene Technology written by Axel R. Zander and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-28 with Science categories.


The 11 th meeting in "Modern Trends in Human Leukemia" took place from June 19 to 21, 1994 in Wilsede in the middle of the Liineburger Heide, South of Hamburg. Interwoven with the Leukemia program was the Nato-sponsored Symposium of the ASI-Series "Gene Technology in Analysis of Malignant and Inherited Human Diseases Related to Development" . The Wilsede meeting was continued on a ship of the Neva leading through lake Ladoga and lake Onega. The topics of both meetings included discussion on recent progress isolation and development of hematopoietic stem cells, genes crucial for development and diseases, methods of gene transfer, application of gene transfer; oncogenes and anti-oncogenes as targets for gene therapy; receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukemias and bone marrow transplantation. The Nato workshop concentrated not only on analysis of cell systems useful for somatic gene therapy, but also on actual themes directly related to correction of human diseases. The latter aspects emphasized themes related to biotechnology, the first part was by nature more general. We also included a few contributions that discussed perspectives for the future of gene therapy and possible relationships to evolution.



Transplantation In Hematology And Oncology Ii


Transplantation In Hematology And Oncology Ii
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Author : W.E. Berdel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Transplantation In Hematology And Oncology Ii written by W.E. Berdel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Transferring hematopoietic stem cells and immune cells has continued to be a promising therapeutic alternative and a fascinating area of cell biology as well as a field of persistent procedural problems. This explains why substantial parts of basic research on cell growth and differentiation, immune tolerance and antitumor effects, gene transfer, minimal residual disease and supportive care have settled around clinical transplantation in hematology and oncology. This second volume updates the current role of allogeneic and autologous transplantation in leukemias, lymphomas and solid cancers, including controversial strategies and novel experimental approaches. Outstanding representatives of leading groups guarantee first-hand information and indicate how we can work and cooperate more effectively to the benefit of our patients.



Biologic Therapy Of Leukemia


Biologic Therapy Of Leukemia
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Author : Matt Kalaycio
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-04-04

Biologic Therapy Of Leukemia written by Matt Kalaycio and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-04 with Medical categories.


Exciting new "biologic" therapies for treating leukemia are appearing so rapidly that clinicians often find it difficult to make informed decisions about their use when making patient treatment decisions. Biologic Therapy of Leukemia summarizes and reviews all the available data concerning these cutting-edge biologic therapies so that practicing clinicians can make the correct patient-care choices. Here the busy physician will find in one convenient place crucial information on the uses and limitations of the major biologic therapies for leukemia, the different biologic strategies for its treatment, the management of patients being treated with such biologic agents, and the current and future role of emerging biologic agents.