Gene Expression Profiling By Microarrays

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Gene Expression Profiling By Microarrays

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Author : Wolf-Karsten Hofmann
language : en
Publisher: Cambridge University Press
Release Date : 2006-06-22

Gene Expression Profiling By Microarrays written by Wolf-Karsten Hofmann and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-22 with Medical categories.

Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.

Microarray Technology

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Author : Paul C.H. Li
language : en
Publisher: Humana
Release Date : 2015-11-28

Microarray Technology written by Paul C.H. Li and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-28 with Medical categories.

This volume provides updates of this established field in both methods and applications, as well as advances in applications of the microarray method to biomarkers such as DNAs, RNAs, proteins, glycans and whole cells. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microarray Technology: Methods and Applications aims to ensure successful results in the further study of this vital field.

Gene Expression Studies Using Affymetrix Microarrays

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Author : Hinrich Gohlmann
language : en
Publisher: CRC Press
Release Date : 2009-07-15

Gene Expression Studies Using Affymetrix Microarrays written by Hinrich Gohlmann and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-15 with Science categories.

The Affymetrix GeneChip system is one of the most widely adapted microarray platforms. However, due to the overwhelming amount of information available, many Affymetrix users tend to stick to the default analysis settings and may end up drawing sub-optimal conclusions. Written by a molecular biologist and a biostatistician with a combined decade of

Microarray Gene Expression Data Analysis

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Author : Helen Causton
language : en
Publisher: John Wiley & Sons
Release Date : 2009-04-01

Microarray Gene Expression Data Analysis written by Helen Causton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-01 with Science categories.

This guide covers aspects of designing microarray experiments and analysing the data generated, including information on some of the tools that are available from non-commercial sources. Concepts and principles underpinning gene expression analysis are emphasised and wherever possible, the mathematics has been simplified. The guide is intended for use by graduates and researchers in bioinformatics and the life sciences and is also suitable for statisticians who are interested in the approaches currently used to study gene expression. Microarrays are an automated way of carrying out thousands of experiments at once, and allows scientists to obtain huge amounts of information very quickly Short, concise text on this difficult topic area Clear illustrations throughout Written by well-known teachers in the subject Provides insight into how to analyse the data produced from microarrays

A Practical Approach To Microarray Data Analysis

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Author : Daniel P. Berrar
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-31

A Practical Approach To Microarray Data Analysis written by Daniel P. Berrar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-31 with Science categories.

In the past several years, DNA microarray technology has attracted tremendous interest in both the scientific community and in industry. With its ability to simultaneously measure the activity and interactions of thousands of genes, this modern technology promises unprecedented new insights into mechanisms of living systems. Currently, the primary applications of microarrays include gene discovery, disease diagnosis and prognosis, drug discovery (pharmacogenomics), and toxicological research (toxicogenomics). Typical scientific tasks addressed by microarray experiments include the identification of coexpressed genes, discovery of sample or gene groups with similar expression patterns, identification of genes whose expression patterns are highly differentiating with respect to a set of discerned biological entities (e.g., tumor types), and the study of gene activity patterns under various stress conditions (e.g., chemical treatment). More recently, the discovery, modeling, and simulation of regulatory gene networks, and the mapping of expression data to metabolic pathways and chromosome locations have been added to the list of scientific tasks that are being tackled by microarray technology. Each scientific task corresponds to one or more so-called data analysis tasks. Different types of scientific questions require different sets of data analytical techniques. Broadly speaking, there are two classes of elementary data analysis tasks, predictive modeling and pattern-detection. Predictive modeling tasks are concerned with learning a classification or estimation function, whereas pattern-detection methods screen the available data for interesting, previously unknown regularities or relationships.

Dna Microarrays Gene Expression Applications

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Author : B.R. Jordan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-01

Dna Microarrays Gene Expression Applications written by B.R. Jordan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-01 with Medical categories.

This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book. It also provides detailed protocols as well as many helpful hints to achieve experimental success and to avoid pitfalls.

Advanced Analysis Of Gene Expression Microarray Data

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Author : Aidong Zhang
language : en
Publisher: World Scientific
Release Date : 2006

Advanced Analysis Of Gene Expression Microarray Data written by Aidong Zhang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.

Focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data. Describes cutting-edge methods for analyzing gene expression microarray data. Coverage includes gene-based analysis, sample-based analysis, pattern-based analysis and visualization tools.

The Analysis Of Gene Expression Data

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Author : Giovanni Parmigiani
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

The Analysis Of Gene Expression Data written by Giovanni Parmigiani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.

This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.

Microarray Bioinformatics

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Author : Dov Stekel
language : en
Publisher: Cambridge University Press
Release Date : 2003-09-08

Microarray Bioinformatics written by Dov Stekel and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-08 with Medical categories.

This book is a comprehensive guide to all of the mathematics, statistics and computing you will need to successfully operate DNA microarray experiments. It is written for researchers, clinicians, laboratory heads and managers, from both biology and bioinformatics backgrounds, who work with, or who intend to work with microarrays. The book covers all aspects of microarray bioinformatics, giving you the tools to design arrays and experiments, to analyze your data, and to share your results with your organisation or with the international community. There are chapters covering sequence databases, oligonucleotide design, experimental design, image processing, normalisation, identifying differentially expressed genes, clustering, classification and data standards. The book is based on the highly successful Microarray Bioinformatics course at Oxford University, and therefore is ideally suited for teaching the subject at postgraduate or professional level.

Statistical Analysis Of Gene Expression Microarray Data

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Author : Terry Speed
language : en
Publisher: CRC Press
Release Date : 2003-03-26

Statistical Analysis Of Gene Expression Microarray Data written by Terry Speed and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-03-26 with Mathematics categories.

Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies