Gene Genealogies Variation And Evolution A Primer In Coalescent Theory
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Gene Genealogies Variation And Evolution A Primer In Coalescent Theory
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Author : Jotun Hein
language : en
Publisher: Oxford University Press, USA
Release Date : 2004-12-09
Gene Genealogies Variation And Evolution A Primer In Coalescent Theory written by Jotun Hein and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-09 with Population genetics categories.
Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Rich in examples and illustrations it is ideal for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine, and for students studying the evolution of human population and disease. It is also an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;Coalescent theory is a central concept in the study of genetic sequence variation that probabilistically describes the genealogy relating the sampled sequences. In this text, besides fulfilling the glaring need for such a book, the authors present this theory in a straightforward and elementary manner and describe the statistical and computational methods used in modelling and analyzing genetic sequence variation. Rich in examples and illustrations the book covers basic concepts, complications arising from geographical structure and recombination before considering aspects of statistical inference based on these models. The book ends with chapters on Gene Mapping, which combines sequence variation data with phenotypic data (such as disease) to define areas of the genome where genes are responsible for the trait, and Human Evolution, a research area that is experiencing a renaissance due to the enormous amounts of data produced in molecular studies. Authored by leading experts, this seminal text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. It is highly suitable for a graduate course in statistics, population, molecular and medical genetics, bioscience and medicine and students studying the evolution of human population and disease, and will be an invaluable reference for bioscientists and statisticians in the pharmaceutical industry and academia - ;an excellent and timely book that should appeal to a variety of people in genetics and applied mathematics. - Professor Montgomery Slatkin (Berkeley);the authors are outstanding experts in the field, and the book is topical and timely. - Professor David Balding (Imperial College);Hein, Schierup and Wiuf have written the first general book on the coalescent. It is an engaging combination of clear mathematical derivation and real data examples. - Professor Joe Felsenstein (University of Washington)
Human Evolutionary Biology
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Author : Michael P. Muehlenbein
language : en
Publisher: Cambridge University Press
Release Date : 2010-07-29
Human Evolutionary Biology written by Michael P. Muehlenbein and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-29 with Social Science categories.
Wide-ranging and inclusive, this text provides an invaluable review of an expansive selection of topics in human evolution, variation and adaptability for professionals and students in biological anthropology, evolutionary biology, medical sciences and psychology. The chapters are organized around four broad themes, with sections devoted to phenotypic and genetic variation within and between human populations, reproductive physiology and behavior, growth and development, and human health from evolutionary and ecological perspectives. An introductory section provides readers with the historical, theoretical and methodological foundations needed to understand the more complex ideas presented later. Two hundred discussion questions provide starting points for class debate and assignments to test student understanding.
Problem Solving Handbook In Computational Biology And Bioinformatics
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Author : Lenwood S. Heath
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-20
Problem Solving Handbook In Computational Biology And Bioinformatics written by Lenwood S. Heath and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-20 with Science categories.
Bioinformatics is growing by leaps and bounds; theories/algorithms/statistical techniques are constantly evolving. Nevertheless, a core body of algorithmic ideas have emerged and researchers are beginning to adopt a "problem solving" approach to bioinformatics, wherein they use solutions to well-abstracted problems as building blocks to solve larger scope problems. Problem Solving Handbook for Computational Biology and Bioinformatics is an edited volume contributed by world renowned leaders in this field. This comprehensive handbook with problem solving emphasis, covers all relevant areas of computational biology and bioinformatics. Web resources and related themes are highlighted at every opportunity in this central easy-to-read reference. Designed for advanced-level students, researchers and professors in computer science and bioengineering as a reference or secondary text, this handbook is also suitable for professionals working in this industry.
Biodiversity And Evolution
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Author : Philippe Grandcolas
language : en
Publisher: Elsevier
Release Date : 2018-04-17
Biodiversity And Evolution written by Philippe Grandcolas and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-17 with Science categories.
Biodiversity and Evolution includes chapters devoted to the evolution and biodiversity of organisms at the molecular level, based on the study of natural collections from the Museum of Natural History. The book starts with an epistemological and historical introduction and ends with a critical overview of the Anthropocene epoch. - Explores the study of natural collections of the Museum of Natural History - Examines evolution and biodiversity at the molecular level - Features an introduction focusing on epistemology and history - Provides a critical overview
Estimating Species Trees
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Author : L. Lacey Knowles
language : en
Publisher: John Wiley and Sons
Release Date : 2011-05-09
Estimating Species Trees written by L. Lacey Knowles and has been published by John Wiley and Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-09 with Science categories.
Recent computational and modeling advances have produced methods for estimating species trees directly, avoiding the problems and limitations of the traditional phylogenetic paradigm where an estimated gene tree is equated with the history of species divergence. The overarching goal of the volume is to increase the visibility and use of these new methods by the entire phylogenetic community by specifically addressing several challenges: (i) firm understanding of the theoretical underpinnings of the methodology, (ii) empirical examples demonstrating the utility of the methodology as well as its limitations, and (iii) attention to technical aspects involved in the actual software implementation of the methodology. As such, this volume will not only be poised to become the quintessential guide to training the next generation of researchers, but it will also be instrumental in ushering in a new phylogenetic paradigm for the 21st century.
Theory And Practice Of Natural Computing
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Author : Carlos Martín-Vide
language : en
Publisher: Springer Nature
Release Date : 2019-11-22
Theory And Practice Of Natural Computing written by Carlos Martín-Vide and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-22 with Computers categories.
This book constitutes the refereed proceedings of the 8th International Conference on Theory and Practice of Natural Computing, TPNC 2019, held in Kingston, ON, Canada, in December 2019. The 15 full papers presented in this book, together with two invited talk, were carefully reviewed and selected from 38 submissions. The papers are organized in topical sections named: Applications of Natural Computing; Evolutionary Computation; Genetic Algorithms, Swarm Intelligence, and Heuristics; Quantum Computing and Information.
Probability And Mathematical Genetics
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Author : N. H. Bingham
language : en
Publisher: Cambridge University Press
Release Date : 2010-07-15
Probability And Mathematical Genetics written by N. H. Bingham and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-15 with Mathematics categories.
No leading university department of mathematics or statistics, or library, can afford to be without this unique text. Leading authorities give a unique insight into a wide range of currently topical problems, from the mathematics of road networks to the genomics of cancer.
Reconstructing Evolution
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Author : Olivier Gascuel
language : en
Publisher: OUP Oxford
Release Date : 2007-06-28
Reconstructing Evolution written by Olivier Gascuel and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-28 with Mathematics categories.
Evolution is a complex process, acting at multiple scales, from DNA sequences and proteins to populations of species. Understanding and reconstructing evolution is of major importance in numerous subfields of biology. For example, phylogenetics and sequence evolution is central to comparative genomics, attempts to decipher genomes, and molecular epidemiology. Phylogenetics is also the focal point of large-scale international biodiversity assessment initiatives such as the 'Tree of Life' project, which aims to build the evolutionary tree for all extant species. Since the pioneering work in phylogenetics in the 1960s, models have become increasingly sophisticated to account for the inherent complexity of evolution. They rely heavily on mathematics and aim at modelling and analyzing biological phenomena such as horizontal gene transfer, heterogeneity of mutation, and speciation and extinction processes. This book presents these recent models, their biological relevance, their mathematical basis, their properties, and the algorithms to infer them from data. A number of subfields from mathematics and computer science are involved: combinatorics, graph theory, stringology, probabilistic and Markov models, information theory, statistical inference, Monte Carlo methods, continuous and discrete algorithmics. This book arises from the Mathematics of Evolution & Phylogenetics meeting at the Mathematical Institute Henri Poincaré, Paris, in June 2005 and is based on the outstanding state-of-the-art reports presented by the conference speakers. Ten chapters - based around five themes - provide a detailed overview of key topics, from the underlying concepts to the latest results, some of which are at the forefront of current research.
The Philosophy Of Evolutionary Theory
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Author : Elliott Sober
language : en
Publisher: Cambridge University Press
Release Date : 2024-02-08
The Philosophy Of Evolutionary Theory written by Elliott Sober and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-08 with Science categories.
Natural selection, mutation, and adaptation are well-known and central topics in Darwin's theory of evolution and in the 20th - and 21st -century theories which grew out of it, but many other important topics are used in evolutionary biology that raise interesting philosophical questions. In this book, Elliott Sober analyses a much larger range of topics, including fitness, altruism, common ancestry, chance, taxonomy, phylogenetic inference, operationalism, reductionism, conventionalism, null hypotheses and default reasoning, instrumentalism versus realism, hypothetico-deductivism, essentialism, falsifiability, the principle of parsimony, the principle of the common cause, causality, determinism versus indeterminism, sensitivity to initial conditions, and the knowability of the past. Sober's clear philosophical analyses of these key concepts, arguments, and methods of inference will be valuable for all readers who want to understand evolutionary biology in both its Darwinian and its contemporary forms.
Research In Computational Molecular Biology
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Author : Alberto Apostolico
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-22
Research In Computational Molecular Biology written by Alberto Apostolico and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-22 with Computers categories.
This book constitutes the refereed proceedings of the 10th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2006, held in Venice, Italy in April 2006. The 40 revised full papers presented together with abstracts of 7 keynote talks were carefully reviewed and selected from 212 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics.