Generalized Inference In Repeated Measures
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Generalized Inference In Repeated Measures
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Author : Samaradasa Weerahandi
language : en
Publisher: John Wiley & Sons
Release Date : 2004-08-24
Generalized Inference In Repeated Measures written by Samaradasa Weerahandi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-08-24 with Mathematics categories.
A complete guide to powerful and practical statistical modeling using MANOVA Numerous statistical applications are time dependent. Virtually all biomedical, pharmaceutical, and industrial experiments demand repeated measurements over time. The same holds true for market research and analysis. Yet conventional methods, such as the Repeated Measures Analysis of Variance (Rm ANOVA), do not always yield exact solutions, obliging practitioners to settle for asymptotic results and approximate solutions. Generalized inference in Multivariate Analysis of Variance (MANOVA), mixed models, and growth curves offer exact methods of data analysis under milder conditions without deviating from the conventional philosophy of statistical inference. Generalized Inference in Repeated Measures is a concise, self-contained guide to the use of these innovative solutions, presenting them as extensions of–rather than alternatives to–classical methods of statistical evaluation. Requiring minimal prior knowledge of statistical concepts in the evaluation of linear models, the book provides exact parametric methods for each application considered, with solutions presented in terms of generalized p-values. Coverage includes: New concepts in statistical inference, with special focus on generalized p-values and generalized confidence intervals One-way and two-way ANOVA, in cases of equal and unequal variances Basic and higher-way mixed models, including testing and estimation of fixed effects and variance components Multivariate populations, including basic inference, comparison, and analysis of variance Basic, widely used repeated measures models including crossover designs and growth curves With a comprehensive set of formulas, illustrative examples, and exercises in each chapter, Generalized Inference in Repeated Measures is ideal as both a comprehensive reference for research professionals and a text for students.
Design And Analysis Of Experiments Volume 3
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Author : Klaus Hinkelmann
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-14
Design And Analysis Of Experiments Volume 3 written by Klaus Hinkelmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-14 with Mathematics categories.
Provides timely applications, modifications, and extensions of experimental designs for a variety of disciplines Design and Analysis of Experiments, Volume 3: Special Designs and Applications continues building upon the philosophical foundations of experimental design by providing important, modern applications of experimental design to the many fields that utilize them. The book also presents optimal and efficient designs for practice and covers key topics in current statistical research. Featuring contributions from leading researchers and academics, the book demonstrates how the presented concepts are used across various fields from genetics and medicinal and pharmaceutical research to manufacturing, engineering, and national security. Each chapter includes an introduction followed by the historical background as well as in-depth procedures that aid in the construction and analysis of the discussed designs. Topical coverage includes: Genetic cross experiments, microarray experiments, and variety trials Clinical trials, group-sequential designs, and adaptive designs Fractional factorial and search, choice, and optimal designs for generalized linear models Computer experiments with applications to homeland security Robust parameter designs and split-plot type response surface designs Analysis of directional data experiments Throughout the book, illustrative and numerical examples utilize SAS®, JMP®, and R software programs to demonstrate the discussed techniques. Related data sets and software applications are available on the book's related FTP site. Design and Analysis of Experiments, Volume 3 is an ideal textbook for graduate courses in experimental design and also serves as a practical, hands-on reference for statisticians and researchers across a wide array of subject areas, including biological sciences, engineering, medicine, and business.
Statistical Methods For Quality Improvement
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Author : Thomas P. Ryan
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20
Statistical Methods For Quality Improvement written by Thomas P. Ryan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Technology & Engineering categories.
Praise for the Second Edition "As a comprehensive statistics reference book for quality improvement, it certainly is one of the best books available." —Technometrics This new edition continues to provide the most current, proven statistical methods for quality control and quality improvement The use of quantitative methods offers numerous benefits in the fields of industry and business, both through identifying existing trouble spots and alerting management and technical personnel to potential problems. Statistical Methods for Quality Improvement, Third Edition guides readers through a broad range of tools and techniques that make it possible to quickly identify and resolve both current and potential trouble spots within almost any manufacturing or nonmanufacturing process. The book provides detailed coverage of the application of control charts, while also exploring critical topics such as regression, design of experiments, and Taguchi methods. In this new edition, the author continues to explain how to combine the many statistical methods explored in the book in order to optimize quality control and improvement. The book has been thoroughly revised and updated to reflect the latest research and practices in statistical methods and quality control, and new features include: Updated coverage of control charts, with newly added tools The latest research on the monitoring of linear profiles and other types of profiles Sections on generalized likelihood ratio charts and the effects of parameter estimation on the properties of CUSUM and EWMA procedures New discussions on design of experiments that include conditional effects and fraction of design space plots New material on Lean Six Sigma and Six Sigma programs and training Incorporating the latest software applications, the author has added coverage on how to use Minitab software to obtain probability limits for attribute charts. new exercises have been added throughout the book, allowing readers to put the latest statistical methods into practice. Updated references are also provided, shedding light on the current literature and providing resources for further study of the topic. Statistical Methods for Quality Improvement, Third Edition is an excellent book for courses on quality control and design of experiments at the upper-undergraduate and graduate levels. the book also serves as a valuable reference for practicing statisticians, engineers, and physical scientists interested in statistical quality improvement.
Geostatistics
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Author : Jean-Paul Chilès
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-08
Geostatistics written by Jean-Paul Chilès and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-08 with Mathematics categories.
Praise for the First Edition ". . . a readable, comprehensive volume that . . . belongs on the desk, close at hand, of any serious researcher or practitioner." Mathematical Geosciences The state of the art in geostatistics Geostatistical models and techniques such as kriging and stochastic multi-realizations exploit spatial correlations to evaluate natural resources, help optimize their development, and address environmental issues related to air and water quality, soil pollution, and forestry. Geostatistics: Modeling Spatial Uncertainty, Second Edition presents a comprehensive, up-to-date reference on the topic, now featuring the latest developments in the field. The authors explain both the theory and applications of geostatistics through a unified treatment that emphasizes methodology. Key topics that are the foundation of geostatistics are explored in-depth, including stationary and nonstationary models; linear and nonlinear methods; change of support; multivariate approaches; and conditional simulations. The Second Edition highlights the growing number of applications of geostatistical methods and discusses three key areas of growth in the field: New results and methods, including kriging very large datasets; kriging with outliers; nonse??parable space-time covariances; multipoint simulations; pluri-gaussian simulations; gradual deformation; and extreme value geostatistics Newly formed connections between geostatistics and other approaches such as radial basis functions, Gaussian Markov random fields, and data assimilation New perspectives on topics such as collocated cokriging, kriging with an external drift, discrete Gaussian change-of-support models, and simulation algorithms Geostatistics, Second Edition is an excellent book for courses on the topic at the graduate level. It also serves as an invaluable reference for earth scientists, mining and petroleum engineers, geophysicists, and environmental statisticians who collect and analyze data in their everyday work.
Handbook Of Monte Carlo Methods
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Author : Dirk P. Kroese
language : en
Publisher: John Wiley & Sons
Release Date : 2013-06-06
Handbook Of Monte Carlo Methods written by Dirk P. Kroese and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-06 with Mathematics categories.
A comprehensive overview of Monte Carlo simulation that explores the latest topics, techniques, and real-world applications More and more of today’s numerical problems found in engineering and finance are solved through Monte Carlo methods. The heightened popularity of these methods and their continuing development makes it important for researchers to have a comprehensive understanding of the Monte Carlo approach. Handbook of Monte Carlo Methods provides the theory, algorithms, and applications that helps provide a thorough understanding of the emerging dynamics of this rapidly-growing field. The authors begin with a discussion of fundamentals such as how to generate random numbers on a computer. Subsequent chapters discuss key Monte Carlo topics and methods, including: Random variable and stochastic process generation Markov chain Monte Carlo, featuring key algorithms such as the Metropolis-Hastings method, the Gibbs sampler, and hit-and-run Discrete-event simulation Techniques for the statistical analysis of simulation data including the delta method, steady-state estimation, and kernel density estimation Variance reduction, including importance sampling, latin hypercube sampling, and conditional Monte Carlo Estimation of derivatives and sensitivity analysis Advanced topics including cross-entropy, rare events, kernel density estimation, quasi Monte Carlo, particle systems, and randomized optimization The presented theoretical concepts are illustrated with worked examples that use MATLAB®, a related Web site houses the MATLAB® code, allowing readers to work hands-on with the material and also features the author's own lecture notes on Monte Carlo methods. Detailed appendices provide background material on probability theory, stochastic processes, and mathematical statistics as well as the key optimization concepts and techniques that are relevant to Monte Carlo simulation. Handbook of Monte Carlo Methods is an excellent reference for applied statisticians and practitioners working in the fields of engineering and finance who use or would like to learn how to use Monte Carlo in their research. It is also a suitable supplement for courses on Monte Carlo methods and computational statistics at the upper-undergraduate and graduate levels.
Sampling
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Author : Steven K. Thompson
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-08
Sampling written by Steven K. Thompson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-08 with Mathematics categories.
Praise for the Second Edition "This book has never had a competitor. It is the only book that takes a broad approach to sampling . . . any good personal statistics library should include a copy of this book." —Technometrics "Well-written . . . an excellent book on an important subject. Highly recommended." —Choice "An ideal reference for scientific researchers and other professionals who use sampling." —Zentralblatt Math Features new developments in the field combined with all aspects of obtaining, interpreting, and using sample data Sampling provides an up-to-date treatment of both classical and modern sampling design and estimation methods, along with sampling methods for rare, clustered, and hard-to-detect populations. This Third Edition retains the general organization of the two previous editions, but incorporates extensive new material—sections, exercises, and examples—throughout. Inside, readers will find all-new approaches to explain the various techniques in the book; new figures to assist in better visualizing and comprehending underlying concepts such as the different sampling strategies; computing notes for sample selection, calculation of estimates, and simulations; and more. Organized into six sections, the book covers basic sampling, from simple random to unequal probability sampling; the use of auxiliary data with ratio and regression estimation; sufficient data, model, and design in practical sampling; useful designs such as stratified, cluster and systematic, multistage, double and network sampling; detectability methods for elusive populations; spatial sampling; and adaptive sampling designs. Featuring a broad range of topics, Sampling, Third Edition serves as a valuable reference on useful sampling and estimation methods for researchers in various fields of study, including biostatistics, ecology, and the health sciences. The book is also ideal for courses on statistical sampling at the upper-undergraduate and graduate levels.
Smoothing Of Multivariate Data
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Author : Jussi Sakari Klemelä
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-04
Smoothing Of Multivariate Data written by Jussi Sakari Klemelä and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-04 with Mathematics categories.
An applied treatment of the key methods and state-of-the-art tools for visualizing and understanding statistical data Smoothing of Multivariate Data provides an illustrative and hands-on approach to the multivariate aspects of density estimation, emphasizing the use of visualization tools. Rather than outlining the theoretical concepts of classification and regression, this book focuses on the procedures for estimating a multivariate distribution via smoothing. The author first provides an introduction to various visualization tools that can be used to construct representations of multivariate functions, sets, data, and scales of multivariate density estimates. Next, readers are presented with an extensive review of the basic mathematical tools that are needed to asymptotically analyze the behavior of multivariate density estimators, with coverage of density classes, lower bounds, empirical processes, and manipulation of density estimates. The book concludes with an extensive toolbox of multivariate density estimators, including anisotropic kernel estimators, minimization estimators, multivariate adaptive histograms, and wavelet estimators. A completely interactive experience is encouraged, as all examples and figurescan be easily replicated using the R software package, and every chapter concludes with numerous exercises that allow readers to test their understanding of the presented techniques. The R software is freely available on the book's related Web site along with "Code" sections for each chapter that provide short instructions for working in the R environment. Combining mathematical analysis with practical implementations, Smoothing of Multivariate Data is an excellent book for courses in multivariate analysis, data analysis, and nonparametric statistics at the upper-undergraduate and graduatelevels. It also serves as a valuable reference for practitioners and researchers in the fields of statistics, computer science, economics, and engineering.
A Primer On Experiments With Mixtures
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Author : John A. Cornell
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-26
A Primer On Experiments With Mixtures written by John A. Cornell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-26 with Mathematics categories.
The concise yet authoritative presentation of key techniques for basic mixtures experiments Inspired by the author's bestselling advanced book on the topic, A Primer on Experiments with Mixtures provides an introductory presentation of the key principles behind experimenting with mixtures. Outlining useful techniques through an applied approach with examples from real research situations, the book supplies a comprehensive discussion of how to design and set up basic mixture experiments, then analyze the data and draw inferences from results. Drawing from his extensive experience teaching the topic at various levels, the author presents the mixture experiments in an easy-to-follow manner that is void of unnecessary formulas and theory. Succinct presentations explore key methods and techniques for carrying out basic mixture experiments, including: Designs and models for exploring the entire simplex factor space, with coverage of simplex-lattice and simplex-centroid designs, canonical polynomials, the plotting of individual residuals, and axial designs Multiple constraints on the component proportions in the form of lower and/or upper bounds, introducing L-Pseudocomponents, multicomponent constraints, and multiple lattice designs for major and minor component classifications Techniques for analyzing mixture data such as model reduction and screening components, as well as additional topics such as measuring the leverage of certain design points Models containing ratios of the components, Cox's mixture polynomials, and the fitting of a slack variable model A review of least squares and the analysis of variance for fitting data Each chapter concludes with a summary and appendices with details on the technical aspects of the material. Throughout the book, exercise sets with selected answers allow readers to test their comprehension of the material, and References and Recommended Reading sections outline further resources for study of the presented topics. A Primer on Experiments with Mixtures is an excellent book for one-semester courses on mixture designs and can also serve as a supplement for design of experiments courses at the upper-undergraduate and graduate levels. It is also a suitable reference for practitioners and researchers who have an interest in experiments with mixtures and would like to learn more about the related mixture designs and models.
Time Series
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Author : Ngai Hang Chan
language : en
Publisher: John Wiley & Sons
Release Date : 2011-01-25
Time Series written by Ngai Hang Chan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-25 with Mathematics categories.
A new edition of the comprehensive, hands-on guide to financial time series, now featuring S-Plus® and R software Time Series: Applications to Finance with R and S-Plus®, Second Edition is designed to present an in-depth introduction to the conceptual underpinnings and modern ideas of time series analysis. Utilizing interesting, real-world applications and the latest software packages, this book successfully helps readers grasp the technical and conceptual manner of the topic in order to gain a deeper understanding of the ever-changing dynamics of the financial world. With balanced coverage of both theory and applications, this Second Edition includes new content to accurately reflect the current state-of-the-art nature of financial time series analysis. A new chapter on Markov Chain Monte Carlo presents Bayesian methods for time series with coverage of Metropolis-Hastings algorithm, Gibbs sampling, and a case study that explores the relevance of these techniques for understanding activity in the Dow Jones Industrial Average. The author also supplies a new presentation of statistical arbitrage that includes discussion of pairs trading and cointegration. In addition to standard topics such as forecasting and spectral analysis, real-world financial examples are used to illustrate recent developments in nonstandard techniques, including: Nonstationarity Heteroscedasticity Multivariate time series State space modeling and stochastic volatility Multivariate GARCH Cointegration and common trends The book's succinct and focused organization allows readers to grasp the important ideas of time series. All examples are systematically illustrated with S-Plus® and R software, highlighting the relevance of time series in financial applications. End-of-chapter exercises and selected solutions allow readers to test their comprehension of the presented material, and a related Web site features additional data sets. Time Series: Applications to Finance with R and S-Plus® is an excellent book for courses on financial time series at the upper-undergraduate and beginning graduate levels. It also serves as an indispensible resource for practitioners working with financial data in the fields of statistics, economics, business, and risk management.
Clinical Trial Design
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Author : Guosheng Yin
language : en
Publisher: John Wiley & Sons
Release Date : 2013-06-07
Clinical Trial Design written by Guosheng Yin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-07 with Medical categories.
A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical Trial Design: Bayesian and Frequentist Adaptive Methods provides comprehensive coverage of both Bayesian and frequentist approaches to all phases of clinical trial design. Before underpinning various adaptive methods, the book establishes an overview of the fundamentals of clinical trials as well as a comparison of Bayesian and frequentist statistics. Recognizing that clinical trial design is one of the most important and useful skills in the pharmaceutical industry, this book provides detailed discussions on a variety of statistical designs, their properties, and operating characteristics for phase I, II, and III clinical trials as well as an introduction to phase IV trials. Many practical issues and challenges arising in clinical trials are addressed. Additional topics of coverage include: Risk and benefit analysis for toxicity and efficacy trade-offs Bayesian predictive probability trial monitoring Bayesian adaptive randomization Late onset toxicity and response Dose finding in drug combination trials Targeted therapy designs The author utilizes cutting-edge clinical trial designs and statistical methods that have been employed at the world's leading medical centers as well as in the pharmaceutical industry. The software used throughout the book is freely available on the book's related website, equipping readers with the necessary tools for designing clinical trials. Clinical Trial Design is an excellent book for courses on the topic at the graduate level. The book also serves as a valuable reference for statisticians and biostatisticians in the pharmaceutical industry as well as for researchers and practitioners who design, conduct, and monitor clinical trials in their everyday work.