Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations

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Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations

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Author : Mashaal Sohail
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-31

Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations written by Mashaal Sohail and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.

Genes And Behaviour

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Author : David J. Hosken
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-15

Genes And Behaviour written by David J. Hosken and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Science categories.

Provides a broad snapshot of recent findings showing how the environment and genes influence behavior The great debate of nature versus nurture rages on — but our understanding of the genetic basis of many behaviors has expanded over the last decade, and there is now very good evidence showing that seemingly complex behaviours can have relatively simple genetic underpinnings, but also that most behaviours have very complicated genetic and environmental architecture. Studies have also clearly shown that behaviors, and other traits, are influenced not just by genes and the environment, but also by the statistical interaction between the two. This book aims to end the nature versus nurture argument by showing that behaviors are nature and nurture and the interaction between the two, and by illustrating how single genes can explain some of the variation in behaviors even when they are seemingly complex. Genes and Behaviour: Beyond Nature-Nurture puts to rest the nature versus nurture dichotomy, providing an up-to-date synopsis of where we are, how far we've come and where we are headed. It considers the effects of a dual-inheritance of genes and culture, and genes and social environment, and highlights how indirect genetic effects can affect the evolution of behavior. It also examines the effect of non-self genes on the behavior of hosts, shines a light on the nature and nurturing of animal minds and invites us to embrace all the complexity nature and nurture generates, and more. Explores exciting new findings about behavior and where we go from here Features contributions by top scholars of the subject Seeks to end the nature versus nurture debate forever Genes and Behaviour: Beyond Nature-Nurture is a unique, and eye-opening read that will appeal to Ph.D. Students, post-doctoral fellows, and researchers in evolution and behavior. Additionally, the book will also be of interest to geneticists, sociologists and philosophers.

Mathematical Population Genetics 1

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Author : Warren J. Ewens
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-01-09

Mathematical Population Genetics 1 written by Warren J. Ewens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-09 with Science categories.

This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Psychological Support By Cognitive Behavioral Therapy For Cystic Fibrosis

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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :

Psychological Support By Cognitive Behavioral Therapy For Cystic Fibrosis written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.

Cystic fibrosis (CF) is a chronic, life-threatening genetic disorder that impacts not only the respiratory and digestive systems but also an individual's psychological well-being. The continuous battle with illness, medical treatments, and the uncertainty of the future can leave profound emotional and mental imprints on patients and their families. In recent years, the importance of psychological support for those affected by CF has come to light, and among the various therapeutic approaches, Cognitive Behavioral Therapy (CBT) stands out as an effective method for managing the psychological toll of chronic illness. This book, Psychological Support by Cognitive Behavioral Therapy for Cystic Fibrosis, is designed to serve as a comprehensive guide for understanding the psychological challenges faced by CF patients and their families. It aims to highlight how CBT can provide effective tools to help them navigate these difficulties, from managing the trauma of diagnosis to coping with the ongoing physical and emotional pain associated with the disorder. The journey of living with a genetic illness like cystic fibrosis is often filled with uncertainty, fear, and emotional strain. For patients, the impact of the disease goes beyond the physical symptoms—it affects their identity, independence, relationships, and self-worth. Families, too, must cope with the overwhelming stress of caregiving, fear of the future, and the emotional exhaustion that comes with chronic illness. In this book, I combine essential knowledge about the biology, genetics, and medical challenges of CF with an introduction to CBT techniques that can be personalized to address these psychological struggles. I delve into the science behind cystic fibrosis and the complexities of genetic mutations that drive the condition. I also explore the impact of hereditary diseases and offer insights into how behavioral genetics and epigenetics play a role in CF and similar conditions. More than just a theoretical discussion, this book offers actionable tools and strategies based on CBT principles to help CF patients and their families manage anxiety, depression, chronic pain, and the everyday emotional hurdles they encounter. From practical tips on pain management to learning how to live a fulfilling life despite the challenges, this book is meant to be a practical guide for both mental health professionals and those directly affected by CF. I hope that this book can offer not only information but also hope and empowerment for individuals and families facing cystic fibrosis. By integrating psychological support into the treatment of CF, it is possible to improve the quality of life for everyone touched by this difficult journey.

Achieving Sustainable Production Of Pig Meat Volume 2

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Author : Emeritus Professor Julian Wiseman
language : en
Publisher: Burleigh Dodds Science Publishing
Release Date : 2017-10-09

Achieving Sustainable Production Of Pig Meat Volume 2 written by Emeritus Professor Julian Wiseman and has been published by Burleigh Dodds Science Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-09 with Technology & Engineering categories.

Reviews latest research on pig genetics and its implications for improved breeding Detailed review of ways of meeting energy, protein, vitamin and mineral requirements of pigs Assesses the role of exogenous enzymes, growth promotors, prebiotics and probiotics in pig nutrition

Psychological Support By Cognitive Behavioral Therapy For Werdnig Hoffmann Disease

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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :

Psychological Support By Cognitive Behavioral Therapy For Werdnig Hoffmann Disease written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.

Werdnig-Hoffmann disease, a severe form of spinal muscular atrophy (SMA), presents not only profound physical challenges but also significant psychological and emotional burdens for those diagnosed and their families. This book, Psychological Support by Cognitive Behavioral Therapy for Werdnig-Hoffmann Disease, seeks to address these psychological dimensions by offering a comprehensive framework for understanding the emotional toll of the disease and providing evidence-based therapeutic strategies to improve quality of life. The journey through a life with Werdnig-Hoffmann disease involves not only managing a progressive and often debilitating physical condition but also navigating the intricate psychological landscape that comes with it. Individuals with this disease, their caregivers, and healthcare providers are often faced with feelings of grief, helplessness, anxiety, and frustration. Coping with such emotions is essential for enhancing the quality of life and ensuring better overall well-being. Cognitive Behavioral Therapy (CBT) has proven to be an effective tool in managing emotional difficulties in chronic illness. CBT focuses on understanding the connection between thoughts, feelings, and behaviors and offers practical tools to alter negative thought patterns, improve emotional regulation, and promote healthier coping strategies. The therapy is particularly beneficial in the context of genetic disorders like Werdnig-Hoffmann disease, where individuals may face unique challenges such as identity struggles, anxiety about genetic transmission, and the emotional impact of medical decisions. This book is intended to provide a solid foundation for clinicians, caregivers, and patients themselves to explore the intersection of mental health and genetic disease. It combines an in-depth understanding of Werdnig-Hoffmann disease with insights into genetics, epigenetics, and hereditary conditions. Through this, I aim to offer not just a therapeutic guide but a pathway to emotional resilience in the face of genetic illness. In addition to providing theoretical and clinical perspectives, this work delves into the application of CBT, addressing common issues faced by patients such as chronic pain, societal pressures, feelings of isolation, and the emotional toll on caregivers. By focusing on practical tools and therapeutic strategies, I hope to empower those affected by Werdnig-Hoffmann disease to manage their emotions, foster resilience, and improve their mental health alongside physical treatment. The integration of personalized therapeutic approaches is emphasized throughout the book, as each individual’s experience with this disease is unique. It is my belief that through this personalized care and the application of CBT techniques, individuals can better navigate the emotional challenges of Werdnig-Hoffmann disease, ultimately leading to improved psychological well-being and quality of life. I would like to dedicate this book to the individuals and families affected by Werdnig-Hoffmann disease and other similar conditions. Your courage, perseverance, and resilience in the face of adversity are the inspiration behind this work. It is my hope that this book serves as a supportive guide in your journey, helping to alleviate some of the emotional burdens and fostering a deeper sense of peace and empowerment.

Microevolution Rate Pattern Process

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Author : Andrew P. Hendry
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Microevolution Rate Pattern Process written by Andrew P. Hendry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

From guppies to Galapagos finches and from adaptive landscapes to haldanes, this compilation of contributed works provides reviews, perspectives, theoretical models, statistical developments, and empirical demonstrations exploring the tempo and mode of microevolution on contemporary to geological time scales. New developments, and reviews, of classic and novel empirical systems demonstrate the strength and diversity of evolutionary processes producing biodiversity within species. Perspectives and theoretical insights expand these empirical observations to explore patterns and mechanisms of microevolution, methods for its quantification, and implications for the evolution of biodiversity on other scales. This diverse assemblage of manuscripts is aimed at professionals, graduate students, and advanced undergraduates who desire a timely synthesis of current knowledge, an illustration of exciting new directions, and a springboard for future investigations in the study of microevolution in the wild.

Genomic And Personalized Medicine

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Author :
language : en
Publisher: Academic Press
Release Date : 2012-10-30

Genomic And Personalized Medicine written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-30 with Science categories.

Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003. - Highly Commended 2013 BMA Medical Book Award for Medicine - More than 100 chapters, from leading researchers, review the many impacts of genomic discoveries in clinical action, including 63 chapters new to this edition - Discusses state-of-the-art genome technologies, including population screening, novel diagnostics, and gene-based therapeutics - Wide and inclusive discussion encompasses the formidable ethical, legal, regulatory and social challenges related to the evolving practice of genomic medicine - Clearly and beautifully illustrated with 280 color figures, and many thousands of references for further reading and deeper analysis

World Malaria Report 2016

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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2017-05-09

World Malaria Report 2016 written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-09 with Medical categories.

The World Malaria Report 2016 summarizes information received from malaria-endemic countries and other sources and updates the analyses presented in the 2015 report. The World Malaria Report is WHO's flagship malaria publication released each year in December. It assesses global and regional malaria trends, highlights progress towards global targets, and describes opportunities and challenges in controling and eliminating the disease. Most of the data presented in this report is for 2015.

Charney And Nestler S Neurobiology Of Mental Illness

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Author : Dennis Charney
language : en
Publisher: Oxford University Press
Release Date : 2025-01-03

Charney And Nestler S Neurobiology Of Mental Illness written by Dennis Charney and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-03 with Education categories.

"The genetic investigation into mental illnesses has progressed rapidly since the mapping of the human genome. Driven by advances in genomic profiling technology, massive genomic datasets are powering the discovery of genetic variation associated to complex traits including mental illness. From severe neurodevelopmental disorders to schizophrenia and depression, genetic variation plays some role in risk. Critically, most mental illnesses are complex, multifactorial and the consequence of a combination of genetic and environmental influences. This chapter will introduce the genome, its variation, and the methods used to identify what variants and genes matter for mental illnesses"--