Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations
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Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations
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Author : Mashaal Sohail
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-31
Genetic Architecture And Evolution Of Complex Traits And Diseases In Diverse Human Populations written by Mashaal Sohail and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Science categories.
Biosocial Surveys
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2008-01-06
Biosocial Surveys written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-06 with Social Science categories.
Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.
Genetics Of Complex Traits Diseases From Under Represented Populations
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Author : Segun Fatumo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-22
Genetics Of Complex Traits Diseases From Under Represented Populations written by Segun Fatumo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-22 with Science categories.
Variation In The Human Genome
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Variation In The Human Genome written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.
Genetic Variation And Human Disease
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Author : Kenneth M. Weiss
language : en
Publisher: Cambridge University Press
Release Date : 1993
Genetic Variation And Human Disease written by Kenneth M. Weiss and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Recent developments in molecular and computational methods have made it possible to identify the genetic basis of any biological trait, and have led to spectacular advances in the study of human disease. This book provides an overview of the concepts and methods needed to understand the genetic basis of biological traits, including disease, in humans. Using examples of qualitative and quantitative phenotypes, Professor Weiss shows how genetic variation may be quantified, and how relationships between genotype and phenotype may be inferred. This book will appeal to many biologists and biological anthropologists interested in the genetic basis of biological traits, as well as to epidemiologists, biomedical scientists, human geneticists and molecular biologists.
In The Light Of Evolution
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Author : National Academy of Sciences
language : en
Publisher:
Release Date : 2007
In The Light Of Evolution written by National Academy of Sciences and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.
Quantitative Genetics And Complex Trait Analysis In Humans The Genetic Basis Of Complex Diseases
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Author : Christine Langhoff
language : en
Publisher: GRIN Verlag
Release Date : 2003-06-07
Quantitative Genetics And Complex Trait Analysis In Humans The Genetic Basis Of Complex Diseases written by Christine Langhoff and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-07 with Science categories.
Essay from the year 2002 in the subject Biology - Genetics / Gene Technology, grade: 2.1 (B), Oxford University (New College), language: English, abstract: Ultimately, the goal of genetics is the analysis of the genotype of organisms. But the genotype can be identified – and therefore studied – only through its phenotypic effect. This means that two genotypes are recognised as different from each other because the phenotypes of their carriers are different. A problem can be seen with this approach as the actual variation between organisms is usually quantitative, not qualitative. Many different genotypes may have the same average phenotype. At the same time, because of environmental variation, two individuals of the same genotype may not have the same phenotype. This lack of a one-to-one correspondence between genotype and phenotype obscures underlying Mendelian genetics. I am going to explore the use of various statistical techniques for studying quantitative traits with application to behavioural traits. I am also going to examine whether there are behavioural traits with sufficiently high heritabilities to give hope for gene searches and I am going to discuss the difficulties that confront molecular geneticists regarding psychiatric genetics.
Evolutionary Genomics
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Author : Maria Anisimova
language : en
Publisher:
Release Date : 2012
Evolutionary Genomics written by Maria Anisimova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Evolutionary genetics categories.
Analysis Of Complex Disease Association Studies
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Author : Eleftheria Zeggini
language : en
Publisher: Academic Press
Release Date : 2010-11-17
Analysis Of Complex Disease Association Studies written by Eleftheria Zeggini and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-17 with Science categories.
According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. Analysis of Complex Disease Association Studies will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available. Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests Extensive list of references including links to tutorial websites Case studies and Tips and Tricks
Genes And Behaviour
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Author : David J. Hosken
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-15
Genes And Behaviour written by David J. Hosken and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Science categories.
Provides a broad snapshot of recent findings showing how the environment and genes influence behavior The great debate of nature versus nurture rages on — but our understanding of the genetic basis of many behaviors has expanded over the last decade, and there is now very good evidence showing that seemingly complex behaviours can have relatively simple genetic underpinnings, but also that most behaviours have very complicated genetic and environmental architecture. Studies have also clearly shown that behaviors, and other traits, are influenced not just by genes and the environment, but also by the statistical interaction between the two. This book aims to end the nature versus nurture argument by showing that behaviors are nature and nurture and the interaction between the two, and by illustrating how single genes can explain some of the variation in behaviors even when they are seemingly complex. Genes and Behaviour: Beyond Nature-Nurture puts to rest the nature versus nurture dichotomy, providing an up-to-date synopsis of where we are, how far we've come and where we are headed. It considers the effects of a dual-inheritance of genes and culture, and genes and social environment, and highlights how indirect genetic effects can affect the evolution of behavior. It also examines the effect of non-self genes on the behavior of hosts, shines a light on the nature and nurturing of animal minds and invites us to embrace all the complexity nature and nurture generates, and more. Explores exciting new findings about behavior and where we go from here Features contributions by top scholars of the subject Seeks to end the nature versus nurture debate forever Genes and Behaviour: Beyond Nature-Nurture is a unique, and eye-opening read that will appeal to Ph.D. Students, post-doctoral fellows, and researchers in evolution and behavior. Additionally, the book will also be of interest to geneticists, sociologists and philosophers.