Genetic Testing For Alzheimer Disease

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Genetic Testing For Alzheimer Disease

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Author : Stephen Garrard Post
language : en
Publisher:
Release Date : 1998

Genetic Testing For Alzheimer Disease written by Stephen Garrard Post and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Family & Relationships categories.

The genetics of Alzheimer disease has been a point of intense concern and immense informational confusion for families in which a loved one is diagnosed with dementia. In recent years, however, scientists have begun to uncover the genetic bases for some forms of Alzheimer disease. Once a chromosomal defect is identified, it becomes possible to devise a test for its presence. The far-reaching implications of such tests are the focus of the present volume. In Genetic Testing for Alzheimer Disease, Stephen G. Post and Peter J. Whitehouse bring together experts from the fields of ethics, genetics, policy, neurology, philosophy, and anthropology to examine the ethical and social aspects of genetic testing for Alzheimer disease. The authors begin by focusing on current genetic findings and their clinical applicability. They then address ethical issues in genetic testing and genetic counseling for Alzheimer disease. They examine social issues such as confidentiality, discrimination, and fairness in health care. Finally, they discuss ways to educate professionals and laypeople regarding these issues. Contributors: Robert H. Binstock, Ph.D.?Thomas D. Bird, M.D. ? Robert Mullan Cook-Deegan, M.D.? Leonard Fleck, Ph.D. ? Atwood D. Gaines, Ph.D, M.P.H. ? Eric T. Juengst, Ph.D. ? Harry Karlinsky, M.D. ? Steven Miles, M.D. ? Thomas H. Murray, Ph.D. ? Stephen G. Post, Ph.D. ? Kimberly A. Quaid, Ph.D. ? Allen D. Roses, M.D. ? Greg A. Sachs, M.D. ? Peter H. St. George-Hyslop, M.D. ? Bonnie Steinbock, Ph.D. ? Arthur B. Zinn, M.D., Ph.D.

Genetic Susceptibility Testing For Alzheimer Disease

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Author : Holly Catherine Gooding
language : en
Publisher:
Release Date : 2004

Genetic Susceptibility Testing For Alzheimer Disease written by Holly Catherine Gooding and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.

Neurologists Practices And Attitudes Regarding Genetic Testing For Alzheimer Disease

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Author : Jamie Chil
language : en
Publisher:
Release Date : 2005

Neurologists Practices And Attitudes Regarding Genetic Testing For Alzheimer Disease written by Jamie Chil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.

Purpose: The purpose of this study was to describe the current practices and attitudes of neurologists regarding genetic testing for Alzheimer disease. Methods: A questionnaire was mailed to 2274 neurologists in the United States. Results: Ninety-three percent of respondents reported familiarity with and 36% reported having ordered apolipoprotein E testing, while 51% reported familiarity with and only 8.8% reported having ordered presenilin 1, presenilin 2, or amyloid precursor protein testing. In five different patient scenarios neurologists indicated a strong correlation in their decision to offer apolipoprotein E and autosomal dominant early-onset genetic testing. Neurologists who were familiar with testing cited different motivations for offering genetic testing than those who were not familiar. Conclusion: Our results indicate that neurologists may not distinguish between the vastly different uses of these genetic tests. Developing a relationship between neurologists and genetic professionals could benefit both groups and could foster comprehensive patient care.

Apolipoprotein E Genotyping In Alzheimer S Disease

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Author : Norman R. Relkin
language : en
Publisher:
Release Date : 1996

Apolipoprotein E Genotyping In Alzheimer S Disease written by Norman R. Relkin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.

This volume addresses what is currently known about the use of ApoE genotyping in diagnosing and predicting Alzheimer's disease. Because ApoE genetic testing has such far-reaching consequences, this volume will be of use not only to those in the medical and scientific community involved in the care of patients with Alzheimer's disease, but also to those concerned with the ethical, legal, epidemiological and public health policy issues as well. A summary will also be included of the results of working groups defining the issues, asking methodological questions, and discussing issues concerning genetic counselling and research-related questions.

Early Diagnosis Of Alzheimer S Disease

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Author : Leonard F. M. Scinto
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-02-09

Early Diagnosis Of Alzheimer S Disease written by Leonard F. M. Scinto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-09 with Medical categories.

Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of new diagnostic approaches to Alzheimer's disease. The authoritative contributors critically survey the most promising current research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this increasingly widespread disease. It will establish a new standard reference guide for all those working with Alzheimer's patients.

Genetic Testing

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Author : Neil F. Sharpe
language : en
Publisher: John Wiley & Sons
Release Date : 2006-01-20

Genetic Testing written by Neil F. Sharpe and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-20 with Science categories.

A complete review of the issues with specific recommendations and guidelines. With over 1,000 tests commercially available, genetic testing is revolutionizing medicine. Health care professionals diagnosing and treating patients today must consider genetic factors, the risks and limitations of genetic testing, and the relevant law. Genetic Testing: Care, Consent, and Liability offers the only complete, practical treatment of the genetic, clinical, ethical, and legal issue surrounding genetic testing. The authors present protocols, policies, and models of care that are currently in use, and explain the legal framework for genetic testing and counseling that has developed in North America, particularly with regard to the law of medical malpractice. This essential book features an international roster of esteemed contributors including, Nancy P. Callanan, Bonnie S. LeRoy, Carole H. Browner, H. Mabel Preloran, Riyana Babul-Hirji, Cheryl Shuman, M.J. Esplen, Maren T. Scheuner, Dena S. Davis, JonBeckwith, Lisa Geller, Mark A. Hall, Andrew R. MacRae, David Chitayat, Roxanne Mykitiuk, Stephanie Turnham, Mireille Lacroix, Jinger G, Hoop, Edwin H, Cook, Jr., S. H. Dinwiddie, Elliot S. Gershon, C. Anthony Rupar, Lynn Holt, Bruce R. Korf, Anne Summers, S. Annie Adams, Daniel L. Van Dyke, Rhett P. Ketterling, Erik C. Thorland, Timothy Caulfield, Lorraine Sheremeta, Richard Gold, Jon F. Merz, David Castle, Peter J. Bridge, JS Parboosingh, Patricia T. Kelly, Julianne M. O'Daniel, Allyn McConkie-Rosell, Beatrice Godard, Bartha Maria Knoppers, David Weisbrot. The coverage also includes: * Genetic screening, including prenatal, neonatal, carrier, and susceptibility testing * Diagnosis, risk assessment, confidentiality, and clinical/legal issues related to follow-up * Interpreting test results and communicating them to patients * psychological considerations * Informed consent * Family history evaluations * Referral to medical geneticists and genetic counselors Genetic Testing Care, Consent, and Liability is a must-have resource for clinical geneticists, genetic counselors, specialists, family physicians, nurses, public health professionals, and medical students.

Genetic Testing Programs For Familial Alzheimer S Disease

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Author :
language : en
Publisher:
Release Date : 1994

Genetic Testing Programs For Familial Alzheimer S Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.

Genetics As Social Practice

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Author : Barbara Prainsack
language : en
Publisher: Routledge
Release Date : 2016-04-22

Genetics As Social Practice written by Barbara Prainsack and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-22 with Social Science categories.

Recent debate about the ethical and regulatory dimensions of developments in genetics has sidelined societal and cultural aspects, which arguably are indispensable for a nuanced understanding of the complexities of the topic. Regulatory and ethical debates benefit from taking seriously this ’third dimension’ of culture, which often determines the configurations and limits of the space within which scientific, ethical and legal debate can take place. To fill this gap, this volume brings together contributions exploring the mutual relationships between genetics, markets, societies and identities in genetics and genomics. It draws upon the recent transdisciplinary debate on how socio-cultural factors influence understandings of ’genetics2.0' and shows how individual and collective identities are challenged or reinforced by cultural meanings and practices of genetics. This book will become a standard reference for everyone seeking to make sense of the controversies and shifts in the field of genetics in the second decade of the twenty-first century.

Genetic Variants In Alzheimer S Disease

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Author : Kevin Morgan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-22

Genetic Variants In Alzheimer S Disease written by Kevin Morgan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-22 with Medical categories.

Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the pathogenesis of Alzheimer’s. These new pathways are now legitimate targets for therapeutic intervention, which can possibly lead to treatment or a possible cure. The aim of this book is to put all of the recent genetic data on these new genes into context. Different genetic variants will be discussed, as well as biomarkers and future possibilities. ​

Laboratory Testing For Neurologic Disorders An Issue Of The Clinics In Laboratory Medicine

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Author : A. Zara Herskovits
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-08-28

Laboratory Testing For Neurologic Disorders An Issue Of The Clinics In Laboratory Medicine written by A. Zara Herskovits and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-28 with Medical categories.

This issue of Clinics in Laboratory Medicine, guest edited by Dr. A. Zara Herskovits, will cover Laboratory Testing for Neurologic Disorders. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: molecular approach to diagnostic testing for children with developmental delay and congenital anomalies, proteopathic and seeding assays (such as RT-QUIC), genetic testing for ALS and FTD, Diagnostic and prognostic testing for Alzheimer’s disease, confounds in the interpretation of paraneoplastic antibody panels, Review of neurologic disease sendout testing at an academic medical center, development of new diagnostic tests for neurologic disorders, assuring quality in laboratory testing for sendout reference tests, diagnostic testing for patients with spinal muscular atrophy, among others.