Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action
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Genetic Toxicology Of Environmental Chemicals
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Author : Clases Ramel
language : en
Publisher: John Wiley & Sons
Release Date : 1986-09
Genetic Toxicology Of Environmental Chemicals written by Clases Ramel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-09 with categories.
Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action
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Author : Claes Ramel
language : en
Publisher:
Release Date : 1986
Genetic Toxicology Of Environmental Chemicals Basic Principles And Mechanisms Of Action written by Claes Ramel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
Genetic Toxicology Of Environmental Chemicals
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Author :
language : en
Publisher:
Release Date : 1986
Genetic Toxicology Of Environmental Chemicals written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Principles Of Genetic Toxicology
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Author : D. Brusick
language : en
Publisher: Springer Science & Business Media
Release Date : 1987-11-30
Principles Of Genetic Toxicology written by D. Brusick and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-11-30 with Medical categories.
The field of genetic toxicology has gone through remarkable development in the seven years since the appearance of the first edition of Principles of Genetic Toxicology. One branch of toxicology research, chemical mutagenesis, has been elucidated and expanded as a result of increased effort, testing, and the sharing of data. This expansion has occurred not only in the industrialized countries, but also in countries that are comparatively less advanced in scientific implementation. These developing countries have taken advan tage of the basic practical methods that were so well described in the first edition of this work. It is significant to note how many centers have been established throughout the world and are now studying the basic concepts and applying them to practical problems such as the detection of genetic effects caused by exposure to chemicals. In fact, there are now toxicology training centers in twelve countries. Genetic toxicology, in addition to being investigated as a science unto itself, has been taught to people in the applied fields so that these techniques may be put to use in solving other biological problems. For these reasons, it is most useful to have an update of the basic methods and their development. Dr. Brusick should be congratulated for doing such an excellent job of assembling a text that will be worthwhile to any researcher who is interested in the principles of genetic toxicology. Alexander Hollaender Council for Research Planning in Biological Sciences, Inc. Washington, D. C.
Applications Of Toxicogenomic Technologies To Predictive Toxicology And Risk Assessment
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2007-11-19
Applications Of Toxicogenomic Technologies To Predictive Toxicology And Risk Assessment written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-19 with Science categories.
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.
Mechanistic Toxicology
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Author : Urs A. Boelsterli
language : en
Publisher: CRC Press
Release Date : 2007-03-23
Mechanistic Toxicology written by Urs A. Boelsterli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-23 with Medical categories.
A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Scientific Frontiers In Developmental Toxicology And Risk Assessment
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2000-12-21
Scientific Frontiers In Developmental Toxicology And Risk Assessment written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-12-21 with Nature categories.
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Current Occupational Environmental Medicine Fourth Edition
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Author : Joseph LaDou
language : en
Publisher: McGraw Hill Professional
Release Date : 2006-10-23
Current Occupational Environmental Medicine Fourth Edition written by Joseph LaDou and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-23 with Medical categories.
Up-to-the-minute, thorough, clinical coverage of common and important occupational and environmental diseases, injuries, and exposures Complete, yet concise, this clinically focused guide offers the definitive overview of common occupational and environmental illnesses, covering their diagnosis and treatment-plus preventive and remedial measures in the workplace and community. With its practical format and emphasis on fundamental topics, CURRENT Occupational and Environmental Medicine is just as essential for students and residents as it is for practicing physicians. You can count on the new fourth edition to deliver the bottom-line answers you need to stay on track in this complex, fast-breaking field. Features: The latest OSHA/NIOSH guidelines for occupational exposure standards Detailed diagnostic checklist for major diseases, injuries, and exposure that help expedite diagnosis and treatment The most clinically relevant perspectives on disability prevention-required reading for the occupational physician Skill-building insights on the importance of ergonomics in the workplace A step-by-step review of how to effectively manage an occupational health and safety program Details on substance abuse and employee assistance programs, health risk analysis, and the legal aspects of occupational and environmental medicine Preventive approaches to terrorist attacks on industry Information-packed primer on epidemiology and biostatistics for the occupational and environmental health specialist Up-to-date references with PMID numbers and peer-reviewed websites
Environmental Health Risk
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Author : Marcelo Larramendy
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-06-16
Environmental Health Risk written by Marcelo Larramendy and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-16 with Science categories.
This book, Environmental Health Risk - Hazardous Factors to Living Species, is intended to provide a set of practical discussions and relevant tools for making risky decisions that require actions to reduce environmental health risk against environmental factors that may adversely impact human health or ecological balances. We aimed to compile information from diverse sources into a single volume to give some real examples extending concepts of those hazardous factors to living species that may stimulate new research ideas and trends in the relevant fields.
Carcinogen Risk Assessment
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Author : Curtis C. Travis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Carcinogen Risk Assessment written by Curtis C. Travis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.