Genetics Of Dyslipidemia
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Genetics Of Dyslipidemia
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Author : Pascale Benlian
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Genetics Of Dyslipidemia written by Pascale Benlian and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Profound mortality rates, due to cardiovascular disease, are a worldwide problem. Cardiovascular disease results from complications of a silent and chronic arterial disease: atherosclerosis. The challenge for the practitioner is adapting diagnostic and therapeutic responses to prevent this common and complex disease. Dyslipidemia, are disorders of the metabolism of soluble transporters of lipids in extracellular spaces of the human body (including blood), called lipoproteins. They are major cardiovascular risk factors, causally related with atherosclerosis and are themselves multifactorial diseases, resulting from interactions between genetic and environmental factors. The study of genetic factors has recently taken a new path with the study of DNA as an experimental object. More than fifty genes of lipoprotein metabolism have been identified in both their physiological actions and their contribution to the pathogenesis of human dyslipidemia. The diversity of observations has refined our current knowledge of the control of lipid metabolism and energy homeostasis in living organisms beyond the limits of the cardiovascular system (e.g., brain, immune system, and development). These studies have given way to a shake-up of former phenotypic classifications, distinguishing new entities, defining targeted therapeutic strategies, providing a basis for different patterns of disease distribution in human populations.
Genetics Of Familial Hypercholesterolemia New Insight
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Author : Alpo Juhani Vuorio
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-02
Genetics Of Familial Hypercholesterolemia New Insight written by Alpo Juhani Vuorio and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-02 with Science categories.
Dyslipidemia Essentials
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Author : Donna Thompson
language : en
Publisher:
Release Date : 2015-02-13
Dyslipidemia Essentials written by Donna Thompson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-13 with categories.
Dyslipidemia has intricate physiopathology, often due to genetic, diet and lifestyle factors. It has various adverse impacts, especially in the development of chronic non-communicable diseases. Important ethnic differences exist due to the prevalence and types of lipid ailment, while elevated serum total and LDL-cholesterol are the main concerns in the developed countries, in other countries hypertriglyceridemia and low HDL-cholesterol are more widespread. The growing cases of obesity, changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health peril, not only for adults but also for children. Various experimental and clinical researches are going on related to the basic mechanisms and treatment of dyslipidemia. This book will deliver an overview of dyslipidemia from distinct facets of physiopathology, ethnic differences, genetics and role in metabolic syndrome.
Dyslipidemia
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Author : Roya Kelishadi
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-02-03
Dyslipidemia written by Roya Kelishadi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Medical categories.
Dyslipidemia has a complex pathophysiology consisting of various genetic, lifestyle, and environmental factors. It has many adverse health impacts, notably in the development of chronic non-communicable diseases. Significant ethnic differences exist due to the prevalence and types of lipid disorders. While elevated serum total- and LDL-cholesterol are the main concern in Western populations, in other countries hypertriglyceridemia and low HDL-cholesterol are more prevalent. The latter types of lipid disorders are considered as components of the metabolic syndrome. The escalating trend of obesity, as well as changes in lifestyle and environmental factors will make dyslipidemia a global medical and public health threat, not only for adults but for the pediatric age group as well. Several experimental and clinical studies are still being conducted regarding the underlying mechanisms and treatment of dyslipidemia. The current book is providing a general overview of dyslipidemia from diverse aspects of pathophysiology, ethnic differences, prevention, health hazards, and treatment.
Coronary Primary Prevention Trial
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Author :
language : en
Publisher:
Release Date : 1984
Coronary Primary Prevention Trial written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Coronary heart disease categories.
Management Of Dyslipidemia
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Author : Wilbert S. Aronow
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-07-21
Management Of Dyslipidemia written by Wilbert S. Aronow and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Medical categories.
Dyslipidemia is a major risk factor for cardiovascular events, cardiovascular mortality, and all-cause mortality. The earlier in life dyslipidemia is treated, the better the prognosis. The current book is an excellent one on dyslipidemia written by experts on this topic. This book includes 12 chapters including 5 on lipids, 4 on hypercholesterolemia in children, and 3 on the treatment of dyslipidemia. This book should be read by all health care professionals taking care of patients, including pediatricians since atherosclerotic cardiovascular disease begins in childhood.
Genetic Variation And Dietary Response
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Author : Artemis P. Simopoulos
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1997-01-01
Genetic Variation And Dietary Response written by Artemis P. Simopoulos and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-01 with Science categories.
This timely volume focuses on genetics and nutrition, and their interaction in the development of chronic diseases. Knowledge of genetic susceptibility to disease will not only help to identify those at higher risk for disease but also to ascertain their response to diet. The prospect of targeting specific dietary treatment at those predicted to gain the most therapeutic benefit clearly has important clinical and economic consequences, particularly in diseases of high prevalence. This book is unique in considering genetic variation in susceptibility to disease, and the importance of specific diets in influencing lipid levels in cardiovascular disease and bone density in osteoporosis. The contributions emphasize that dietary response is dependent on the genetic variant and that specific dietary recommendations rather than universal ones are needed for the prevention and management of chronic diseases. Bringing together vital information for the first time, this book is important reading for physicians, nutritionists, dietitians, geneticists, physiologists, molecular biologists, food technologists and policymakers.
High Density Lipoproteins
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Author : Arnold von Eckardstein
language : en
Publisher: Springer
Release Date : 2015-01-13
High Density Lipoproteins written by Arnold von Eckardstein and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-13 with Medical categories.
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
Cardiovascular Genetics And Genomics For The Cardiologist
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Author : Victor J. Dzau, MD
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Cardiovascular Genetics And Genomics For The Cardiologist written by Victor J. Dzau, MD and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.
Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew – both pioneers in the area – help cardiologists understand: • how cardiovascular genetics may remodel the way cardiovascular medicine is practiced • what material has immediate relevance to the practicing clinician • how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses: • cardiovascular single gene disorders • cardiovascular polygenic disorders • therapies and applications Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.
Dyslipidemias
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Author : Abhimanyu Garg
language : en
Publisher: Springer
Release Date : 2015-05-11
Dyslipidemias written by Abhimanyu Garg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-11 with Medical categories.
Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, internists, and geneticists. For the last twenty years, there has been a growing recognition worldwide of the importance of managing dyslipidemia for the primary and secondary prevention of atherosclerotic vascular disease, especially coronary heart disease. This has been mainly due to the publication of the guidelines of National Cholesterol Education Program’s Adult Treatment Panel and Pediatric Panel from the United States. These guidelines have stimulated generation of similar recommendations from all over the world, particularly Europe, Canada, Australia and Asia. Developed by a renowned group of leading international experts, the book offers state-of-the-art chapters that are peer-reviewed and represent a comprehensive assessment of the field. A major addition to the literature, Dyslipidemias: Pathophysiology, Evaluation and Management is a gold-standard level reference for all clinicians who are challenged to provide the best care and new opportunities for patients with dyslipidemias.