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Genetics Of Obesity Syndromes


Genetics Of Obesity Syndromes
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Genetics Of Obesity Syndromes


Genetics Of Obesity Syndromes
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Author : Philip R. Beales
language : en
Publisher: Oxford University Press
Release Date : 2008-08-29

Genetics Of Obesity Syndromes written by Philip R. Beales and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-29 with Medical categories.


Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.



Genetics Of Obesity Syndromes


Genetics Of Obesity Syndromes
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Author : Philip R. Beales
language : en
Publisher: OUP USA
Release Date : 2009-07-09

Genetics Of Obesity Syndromes written by Philip R. Beales and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-09 with Medical categories.


Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.



The Genetics Of Obesity


The Genetics Of Obesity
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Author : Struan F.A. Grant
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09

The Genetics Of Obesity written by Struan F.A. Grant and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.


In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), h has been more robustly observed by others. Studies from both FTO knock out and FTO overexpression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book will give a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). This book will cover this state of the art technology and its application to obesity in great detail. Topics covered will include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.​



The Genetics Of Obesity


The Genetics Of Obesity
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Author : Claude Bouchard
language : en
Publisher: CRC Press
Release Date : 2020-08-11

The Genetics Of Obesity written by Claude Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.


This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.



The Genetics Of Obesity


The Genetics Of Obesity
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Author : Claude Bouchard
language : en
Publisher: CRC Press
Release Date : 2020-08-11

The Genetics Of Obesity written by Claude Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.


This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.



Genes And Obesity


Genes And Obesity
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-12-17

Genes And Obesity written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-17 with Science categories.


A number of genes have been identified that are associated with an increased body mass index (BMI), the standard measurement of obesity. By analyzing these genes, researchers hope to gain a better understanding of what causes obesity and develop ways to tackle the problem. The study of genes and obesity could lead to new treatments. Genes and Obesity reviews the latest developments in the field. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields



Genetics Of Monogenic And Syndromic Obesity


Genetics Of Monogenic And Syndromic Obesity
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-06-02

Genetics Of Monogenic And Syndromic Obesity written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-02 with Science categories.


Genetics of Monogenic and Syndromic Obesity is the latest volume in the Progress in Molecular Biology and Translational Science series. Contains contributions from leading authorities Informs and updates on all the latest developments in the field



Obesity And Metabolism


Obesity And Metabolism
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Author : Márta Korbonits
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2008-01-01

Obesity And Metabolism written by Márta Korbonits and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-01 with Medical categories.


It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.



Genetic Obesity


Genetic Obesity
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Author : Lotte Kleinendorst
language : en
Publisher:
Release Date : 2021

Genetic Obesity written by Lotte Kleinendorst and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.




Obesity


Obesity
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Author : Andrew Ternouth
language : en
Publisher:
Release Date : 2009

Obesity written by Andrew Ternouth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.