Genes And Obesity
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The Genetics Of Obesity
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Author : Claude Bouchard
language : en
Publisher: CRC Press
Release Date : 2020-08-11
The Genetics Of Obesity written by Claude Bouchard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.
This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.
The Genetics Of Obesity
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Author : Stephanie Watson
language : en
Publisher: The Rosen Publishing Group, Inc
Release Date : 2008-08-15
The Genetics Of Obesity written by Stephanie Watson and has been published by The Rosen Publishing Group, Inc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-15 with Juvenile Nonfiction categories.
Explains obesity and how genes can be linked to the condition.
The Genetics Of Obesity
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Author : Struan F.A. Grant
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09
The Genetics Of Obesity written by Struan F.A. Grant and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.
In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), h has been more robustly observed by others. Studies from both FTO knock out and FTO overexpression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book will give a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). This book will cover this state of the art technology and its application to obesity in great detail. Topics covered will include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.
Genes And Obesity
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Author :
language : en
Publisher: Academic Press
Release Date : 2010-12-17
Genes And Obesity written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-17 with Science categories.
A number of genes have been identified that are associated with an increased body mass index (BMI), the standard measurement of obesity. By analyzing these genes, researchers hope to gain a better understanding of what causes obesity and develop ways to tackle the problem. The study of genes and obesity could lead to new treatments. Genes and Obesity reviews the latest developments in the field. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields
Fat Wars
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Author : Ellen Ruppel Shell
language : en
Publisher: Atlantic Books Ltd
Release Date : 2015-05-18
Fat Wars written by Ellen Ruppel Shell and has been published by Atlantic Books Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-18 with Self-Help categories.
We are facing a gathering health crisis of epic proportions. The crisis is obesity and the diseases linked to it - hypertension, diabetes, cancer and heart disease. While multinational drug companies race to find a cure, the problem only worsens, with experts declaring thatthe UK is the second most obese nation on the planet and that 31,000 death a year in Britain are obesity-related. In a rare blend of cutting-edge science, history and personal stories, Shell builds a compelling narrative culminating in a thought-provoking - and radical - call to arms. This is the definitive account of how the western world got fat - and what we can do about it. 'A fascinating book... Shell has a droll manner and narrative gift that transforms the most unpromising chapters of obesity R&D into observant little dramas... An illuminating history of overweight' -- Catherine Bennett, Guardian 'A real steel magnolia of a book. A political fist clenched inside a scientific glove. Charmingly written with plenty of human interest and colour, its underlying message is nonetheless clear and radical.' -- Jerome Burne, Financial Times
Genetics Of Obesity Syndromes
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Author : Philip R. Beales
language : en
Publisher: Oxford University Press
Release Date : 2008-08-29
Genetics Of Obesity Syndromes written by Philip R. Beales and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-29 with Medical categories.
Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.
Genomics Obesity And The Struggle Over Responsibilities
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Author : Michiel Korthals
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-14
Genomics Obesity And The Struggle Over Responsibilities written by Michiel Korthals and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-14 with Philosophy categories.
This volume addresses the overlapping aspects of the fields of genomics, obesity and (non-) medical ethics. It is unique in its examination of the implications of genomics for obesity from an ethical perspective. Genomics covers the sciences and technologies involved in the pathways that DNA takes until the organism is completely built and sustained: the range of genes (DNA), transcriptor factors, enhancers, promoters, RNA (copy of DNA), proteins, metabolism of cell, cellular interactions, organisms. Genomics offers a holistic approach, which, when applied to obesity, can have surprising and disturbing implications for the existing networks tackling this phenomenon. The ethical concerns and consideration presented are inspired by the interaction between the procedural perspective emphasizing the necessity of consultative and participatory organizational relationships in the new gray zones between medicine and food, and the substantive perspective that both cherishes individual autonomy and embeds it in socio-cultural contexts.
Genetics Of Obesity Syndromes
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Author : Philip R. Beales
language : en
Publisher: OUP USA
Release Date : 2009-07-09
Genetics Of Obesity Syndromes written by Philip R. Beales and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-09 with Medical categories.
Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.
Gene Eating
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Author : Giles Yeo
language : en
Publisher: Hachette UK
Release Date : 2018-12-27
Gene Eating written by Giles Yeo and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-27 with Health & Fitness categories.
'It is rare to find a book, written by a world-class scientist, that is both informative and entertaining. Giles not only delves into the science of obesity but, with honesty and great precision, skewers many of the more foolish fad diets out there. ' DR MICHAEL MOSLEY, bestselling author of The 8-Week Blood Sugar Diet 'A hard-to-fault book written in a way that entertains as well as it informs ... Yeo's study of human appetite is packed with insights and revelations, incorporating up-to-date scientific thinking ... It's an anti-diet diet book you can trust' DAILY EXPRESS 'I really enjoy working with Giles - he makes so much sense, and cuts through the confusion about diet and health with refreshing directness. His excellent book Gene Eating busts myths and homes in on what you really need need to know. It's been a genuine help to me and I'm sure it will be to everyone who reads it.' HUGH FEARNLEY-WHITTINGSTALL 'Dr Yeo is a leading scientist in the field of obesity and one of our best science communicators. Everyone worried about their weight ought to read this book to digest its message about the importance of genetics.' ROBERT PLOMIN, author of Blueprint: How DNA Makes Us Who We Are 'An excellent and engaging book, but also an important one. It is about time that a serious, respected academic provided a voice of reason' Anthony Warner aka THE ANGRY CHEF 'Gene Eating is just a fantastic book exactly as you'd expect - but more so. Mainly it's very funny, packed with science and trivia and genuinely helpful weightloss and nutrition info' DR CHRIS VAN TULLEKEN, the BBC Why are we all getting fatter? Why are some people hungrier than others? And why don't diets work? In an age of misinformation and pseudo-science, the world is getting fatter and the diet makers are getting richer. So how do we break this cycle that's killing us all? Drawing on the very latest science and his own genetic research at Cambridge University, Dr Giles Yeo has written the seminal 'anti-diet' diet book. Exploring the history of our food, debunking marketing nonsense and toxic diet advice, and confronting the advocates of 'clean eating', Dr Giles translates his pioneering research into an engaging, must-read study of the human appetite. Inspiring and revelatory, Gene Eating is an urgent and essential book that will empower us all with the facts we need to establish healthy relationships with food - and change the way we eat
Gene By Environment Interactions Between Three Candidate Genes For Obesity And Omega 3 Polyunsaturated Fatty Acids
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Author : Renee Leigh Pasker
language : en
Publisher:
Release Date : 2008
Gene By Environment Interactions Between Three Candidate Genes For Obesity And Omega 3 Polyunsaturated Fatty Acids written by Renee Leigh Pasker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Yupik Eskimos categories.
"Multi-factorial diseases, like obesity, are caused by genetic and environmental factors. Few studies examine potential interactions between genetic and environmental factors. Understanding these interactions can lead to better disease prevention. One important environmental factor related to obesity is omega-3 fatty acids. Yup'ik Eskimos consume a high amount of two omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). This study examined 10 single nucleotide polymorphisms (SNPs) in three genes: ADIPOQ, PPARG, and PPARGC1A. Also, 7 obesity phenotypes were examined: BMI, percent body fat, waist circumference, sum of skin-folds, plasma adiponectin, plasma triglycerides, and HDL cholesterol. Associations between these SNPs and phenotypes in 981 related Yup'ik Eskimos were examined using mixed models. Interactions were investigated with these SNPs and ð15N, a biomarker used to determine intake of EPA and DHA. The results showed that EPA and DHA modify the expression of all three genes. Additionally, SNPs in all three genes were associated with one or more obesity phenotypes. The most statistically significant results were with two SNPs in ADIPOQ and plasma adiponectin. This study supports the role of these genes in the etiology of obesity. Finally, this study demonstrates that these genes are influenced by EPA and DHA"--Leaf iii.