Genome Mapping And Genomics In Human And Non Human Primates
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Genome Mapping And Genomics In Human And Non Human Primates
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Author : Ravindranath Duggirala
language : en
Publisher: Springer
Release Date : 2015-03-25
Genome Mapping And Genomics In Human And Non Human Primates written by Ravindranath Duggirala and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-25 with Science categories.
This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.
Monkeys Apes And Humans
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Author : Michael A. Huffman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-20
Monkeys Apes And Humans written by Michael A. Huffman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-20 with Medical categories.
(tentative) What bring about biodiversity are not always genes. As is the case with humans, cultural diversity of non-human animals has also been found. Most of well-known examples of animal cultures are those of food acquisition behaviors, such as sweet-potato-washing by Japanese macaques and nut-cracking by chimpanzees. First author, Naofumi Nakagawa, introduces cultural diversity of social behaviors in wild Japanese macaques, such as the embracing behaviors between adult females in a wild group in each population of Yakushima, Kinkazan, and Shimokita. The subtle local difference in embracing can be identified as the first evidence for social customs in wild Japanese macaques. The next author, Michael A. Huffman, introduces the self-medicative behavior in non-human primates, which is a relatively new study in primatology. Parasites cause a variety of diseases that affect the behavior and reproductive fitness of an individual. He classifies health maintenance and self-medicative behaviors observed in non-human primates into four levels. Not only humans but also apes and monkeys are maintaining their health. The third authors, Hiroo Imai, Masaki Tomonaga, and Yasuhiro Go, are promoting comparative cognitive sciences of primates including human and chimpanzees. Recently, human personal genome projects progresses as related to the phenotypes including cognition, while there was no similar project for non-human primates. They started personal genome and transcriptome projects of chimpanzees in Primate Research Institute, Kyoto University, years ago. They introduce recent progresses of the project and related results based on the primate genome sciences.
Ancestors In Our Genome
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Author : Eugene E. Harris (Professor)
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
Ancestors In Our Genome written by Eugene E. Harris (Professor) and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Science categories.
Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.
Mapping And Sequencing The Human Genome
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Author : Committee on Mapping and Sequencing the Human Genome
language : en
Publisher:
Release Date : 1988
Mapping And Sequencing The Human Genome written by Committee on Mapping and Sequencing the Human Genome and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
Annotation Report of the Committee on [title]. Discusses the desirability and feasibility of a gigantic project. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com).
Primate Cytogenetics
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Author : Stefan Müller
language : en
Publisher: S Karger Ag
Release Date : 2005
Primate Cytogenetics written by Stefan Müller and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
Primate molecular genetics, cytogenetics and genomics currently form a highly dynamic field of research. This has not occurred simply because of advances in technology. It is largely a consequence of the key insight that many aspects of human genome functioning can be better understood when knowledge about the conservation of, and changes in, genome organization during the course of evolution is integrated. Studies of our closest phylogenomic relatives, the nonhuman primates, can provide detailed information on the molecular mechanisms that shape the human genome. Consequently the chimpanzee genome project put forth the first chimpanzee draft sequence and its alignment with the human reference sequence in December 2003. Including review articles and original investigations, this Cytogenetic and Genome Research single topic issue bundles various different perspectives and provides a broad overview of the present knowledge about molecular cytogenetics, genome organization and evolution of primates. It will be of great interest to researchers and geneticists in the fields of primatology, anthropology, molecular phylogeny, evolution, human genetics and genome research.
Heritable Human Genome Editing
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Author : The Royal Society
language : en
Publisher: National Academies Press
Release Date : 2021-01-16
Heritable Human Genome Editing written by The Royal Society and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-16 with Medical categories.
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Genome Mapping And Genomics In Arthropods
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Author : Wayne Hunter
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-10
Genome Mapping And Genomics In Arthropods written by Wayne Hunter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-10 with Science categories.
The series "Genome Mapping and Genomics in Animals" provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world. The huge amount of information hitherto dispersed in journals is now available in this clearly structured reference work. Arthropods covered here include honeybee, bumblebee, the parasitic Jewel Wasp, silkworm, pea aphid, mosquito, Hessian fly and tick.
Genome Mapping And Genomics In Fishes And Aquatic Animals
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Author : Thomas D. Kocher
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-07
Genome Mapping And Genomics In Fishes And Aquatic Animals written by Thomas D. Kocher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-07 with Science categories.
Mapping of animal genomes has generated huge databases and several new concepts and strategies, which are useful to elucidate origin, evolution and phylogeny. Genetic and physical maps of genomes further provide precise details on chromosomal location, function, expression and regulation of academically and economically important genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on a large variety of selected animal systems, contributed by leading scientists from around the world. This volume summarizes the first era of genomic studies of aquaculture species, in which the tools and resources necessary to support whole-genome sequencing were developed. These tools will enhance efforts toward selective breeding of aquaculture species. Included in this volume are summaries of work on salmonids, cyprinids, catfish, tilapias, European sea bass, Japanese flounder, shrimps and oysters.
Chimpanzees In Biomedical And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-01-05
Chimpanzees In Biomedical And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-05 with Science categories.
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Exploring Horizons For Domestic Animal Genomics
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2002-08-27
Exploring Horizons For Domestic Animal Genomics written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-08-27 with Science categories.
Recognizing the important contributions that genomic analysis can make to agriculture, production and companion animal science, evolutionary biology, and human health with respect to the creation of models for genetic disorders, the National Academies convened a group of individuals to plan a public workshop that would: (1) assess these contributions; (2) identify potential research directions for existing genomics programs; and (3) highlight the opportunities of a coordinated, multi-species genomics effort for the science and policymaking communities. Their efforts culminated in a workshop sponsored by the U.S. Department of Agriculture, Department of Energy, National Science Foundation, and the National Institutes of Health. The workshop was convened on February 19, 2002. The goal of the workshop was to focus on domestic animal genomics and its integration with other genomics and functional genomics projects.