Genomic Analysis Using Digital Signal Processing
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Genomic Analysis Using Digital Signal Processing
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Author : Alejandro Morales
language : en
Publisher: Academic Press
Release Date : 2019-03
Genomic Analysis Using Digital Signal Processing written by Alejandro Morales and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03 with Science categories.
Genomic Analysis Using Digital Signal Processing presents some of the recent advances and challenges in signal processing analysis of genomic sequences, showing how the use of signal processing tools can offer interpretation for the study of genomics and biological function. The book covers several major areas, including mapping the problem, noise in genomic signals, segmentation and signal processing tools, and applications of genomic signal processing. Researchers and graduate students in signal processing, biomedical engineering and bioinformatics will find this book a very useful reference on how signal processing methods can be used for genomic analysis. Covers signal processing methods for genomic analysis with a list of existing software Provides full implementation of signal processing tools with biological interpretation Includes examples of signal processing applications for genomic analysis
Genomic Sequence Analysis For Exon Prediction Using Adaptive Signal Processing Algorithms
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Author : Md. Zia Ur Rahman
language : en
Publisher: CRC Press
Release Date : 2021-06-30
Genomic Sequence Analysis For Exon Prediction Using Adaptive Signal Processing Algorithms written by Md. Zia Ur Rahman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-30 with Science categories.
This book addresses the issue of improving the accuracy in exon prediction in DNA sequences using various adaptive techniques based on different performance measures that are crucial in disease diagnosis and therapy. First, the authors present an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods, followed by a review of literature starting with the biological background of genomic sequence analysis. Next, they cover various theoretical considerations of adaptive filtering techniques used for DNA analysis, with an introduction to adaptive filtering, properties of adaptive algorithms, and the need for development of adaptive exon predictors (AEPs) and structure of AEP used for DNA analysis. Then, they extend the approach of least mean squares (LMS) algorithm and its sign-based realizations with normalization factor for DNA analysis. They also present the normalized logarithmic-based realizations of least mean logarithmic squares (LMLS) and least logarithmic absolute difference (LLAD) adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants. This book ends with an overview of the goals achieved and highlights the primary achievements using all proposed techniques. This book is intended to provide rigorous use of adaptive signal processing algorithms for genetic engineering, biomedical engineering, and bioinformatics and is useful for undergraduate and postgraduate students. This will also serve as a practical guide for Ph.D. students and researchers and will provide a number of research directions for further work. Features Presents an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods Covers various theoretical considerations of adaptive filtering techniques used for DNA analysis, introduction to adaptive filtering, properties of adaptive algorithms, need for development of adaptive exon predictors (AEPs), and structure of AEP used for DNA analysis Extends the approach of LMS algorithm and its sign-based realizations with normalization factor for DNA analysis Presents the normalized logarithmic-based realizations of LMLS and LLAD adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants Provides an overview of the goals achieved and highlights the primary achievements using all proposed techniques Dr. Md. Zia Ur Rahman is a professor in the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His current research interests include adaptive signal processing, biomedical signal processing, genetic engineering, medical imaging, array signal processing, medical telemetry, and nanophotonics. Dr. Srinivasareddy Putluri is currently a Software Engineer at Tata Consultancy Services Ltd., Hyderabad. He received his Ph.D. degree (Genomic Signal Processing using Adaptive Signal Processing algorithms) from the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His research interests include genomic signal processing and adaptive signal processing. He has published 15 research papers in various journals and proceedings. He is currently a reviewer of publishers like the IEEE Access and IGI.
Genomic Signal Processing
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Author : Ilya Shmulevich
language : en
Publisher: Princeton University Press
Release Date : 2014-09-08
Genomic Signal Processing written by Ilya Shmulevich and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-08 with Science categories.
Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.
Genomic Signal Processing And Statistics
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Author : Edward R. Dougherty
language : en
Publisher: Hindawi Publishing Corporation
Release Date : 2005
Genomic Signal Processing And Statistics written by Edward R. Dougherty and has been published by Hindawi Publishing Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with DNA microarrays categories.
Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.
Data Analytics In Bioinformatics
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Author : Rabinarayan Satpathy
language : en
Publisher: John Wiley & Sons
Release Date : 2021-01-20
Data Analytics In Bioinformatics written by Rabinarayan Satpathy and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-20 with Computers categories.
Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.
Genomic Sequence Analysis For Exon Prediction Using Adaptive Signal Processing Algorithms
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Author : Md. Zia Ur Rahman
language : en
Publisher: CRC Press
Release Date : 2021-06-30
Genomic Sequence Analysis For Exon Prediction Using Adaptive Signal Processing Algorithms written by Md. Zia Ur Rahman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-30 with Science categories.
This book addresses the issue of improving the accuracy in exon prediction in DNA sequences using various adaptive techniques based on different performance measures that are crucial in disease diagnosis and therapy. First, the authors present an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods, followed by a review of literature starting with the biological background of genomic sequence analysis. Next, they cover various theoretical considerations of adaptive filtering techniques used for DNA analysis, with an introduction to adaptive filtering, properties of adaptive algorithms, and the need for development of adaptive exon predictors (AEPs) and structure of AEP used for DNA analysis. Then, they extend the approach of least mean squares (LMS) algorithm and its sign-based realizations with normalization factor for DNA analysis. They also present the normalized logarithmic-based realizations of least mean logarithmic squares (LMLS) and least logarithmic absolute difference (LLAD) adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants. This book ends with an overview of the goals achieved and highlights the primary achievements using all proposed techniques. This book is intended to provide rigorous use of adaptive signal processing algorithms for genetic engineering, biomedical engineering, and bioinformatics and is useful for undergraduate and postgraduate students. This will also serve as a practical guide for Ph.D. students and researchers and will provide a number of research directions for further work. Features Presents an overview of genomics engineering, structure of DNA sequence and its building blocks, genetic information flow in a cell, gene prediction along with its significance, and various types of gene prediction methods Covers various theoretical considerations of adaptive filtering techniques used for DNA analysis, introduction to adaptive filtering, properties of adaptive algorithms, need for development of adaptive exon predictors (AEPs), and structure of AEP used for DNA analysis Extends the approach of LMS algorithm and its sign-based realizations with normalization factor for DNA analysis Presents the normalized logarithmic-based realizations of LMLS and LLAD adaptive algorithms that include normalized LMLS (NLMLS) algorithm, normalized LLAD (NLLAD) algorithm, and their signed variants Provides an overview of the goals achieved and highlights the primary achievements using all proposed techniques Dr. Md. Zia Ur Rahman is a professor in the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His current research interests include adaptive signal processing, biomedical signal processing, genetic engineering, medical imaging, array signal processing, medical telemetry, and nanophotonics. Dr. Srinivasareddy Putluri is currently a Software Engineer at Tata Consultancy Services Ltd., Hyderabad. He received his Ph.D. degree (Genomic Signal Processing using Adaptive Signal Processing algorithms) from the Department of Electronics and Communication Engineering at Koneru Lakshmaiah Educational Foundation (K. L. University), Guntur, India. His research interests include genomic signal processing and adaptive signal processing. He has published 15 research papers in various journals and proceedings. He is currently a reviewer of publishers like the IEEE Access and IGI.
Advanced Methods Of Biomedical Signal Processing
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Author : Sergio Cerutti
language : en
Publisher: John Wiley & Sons
Release Date : 2011-05-10
Advanced Methods Of Biomedical Signal Processing written by Sergio Cerutti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-10 with Science categories.
This book grew out of the IEEE-EMBS Summer Schools on Biomedical Signal Processing, which have been held annually since 2002 to provide the participants state-of-the-art knowledge on emerging areas in biomedical engineering. Prominent experts in the areas of biomedical signal processing, biomedical data treatment, medicine, signal processing, system biology, and applied physiology introduce novel techniques and algorithms as well as their clinical or physiological applications. The book provides an overview of a compelling group of advanced biomedical signal processing techniques, such as multisource and multiscale integration of information for physiology and clinical decision; the impact of advanced methods of signal processing in cardiology and neurology; the integration of signal processing methods with a modelling approach; complexity measurement from biomedical signals; higher order analysis in biomedical signals; advanced methods of signal and data processing in genomics and proteomics; and classification and parameter enhancement.
Signal Processing Methods For Genomic Sequence Analysis
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Author : Byung-Jun Yoon
language : en
Publisher:
Release Date : 2007
Signal Processing Methods For Genomic Sequence Analysis written by Byung-Jun Yoon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Bioinformatics categories.
How Covid 19 Is Accelerating The Digital Revolution
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Author : R. Anandan
language : en
Publisher: Springer Nature
Release Date : 2022-05-18
How Covid 19 Is Accelerating The Digital Revolution written by R. Anandan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-18 with Computers categories.
This book explores how digital technologies have proved to be a useful and necessary tool to help ensure that local and regional governments on the frontline of the emergency can continue to provide essential public services during the COVID-19 crisis. Indeed, as the demand for digital technologies grows, local and regional governments are increasingly committed to improving the lives of their citizens under the principles of privacy, freedom of expression and democracy. The Digital Revolution began between the late 1950s and 1970s and represents the evolution of technology from the mechanical and analog to the digital. The advent of digital technology has also changed how humans communicate – today using computers, smartphones and the internet. Further, the digital revolution has made a tremendous wealth of information accessible to virtually everyone. In turn, the book focuses on key challenges for local and regional governments concerning digital technologies during this crisis, e.g. the balance between privacy and security, the digital divide, and accessibility. Privacy is a challenge in the mitigation of COVID-19, as governments rely on digital technologies like contact-tracking apps and big data to help trace peoples’ patterns and movements. While these methods are controversial and may infringe on rights to privacy, they also appear to be effective measures for rapidly controlling and limiting the spread of the virus. Next, the book discusses the 10 technology trends that can help build a resilient society, as well as their effects on how we do business, how we work, how we produce goods, how we learn, how we seek medical services and how we entertain ourselves. Lastly, the book addresses a range of diversified technologies, e.g. Online Shopping and Robot Deliveries, Digital and Contactless Payments, Remote Work, Distance Learning, Telehealth, Online Entertainment, Supply Chain 4.0, 3D Printing, Robotics and Drones, 5G, and Information and Communications Technology (ICT).
Signal Processing And Machine Learning For Biomedical Big Data
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Author : Ervin Sejdic
language : en
Publisher: CRC Press
Release Date : 2018-07-04
Signal Processing And Machine Learning For Biomedical Big Data written by Ervin Sejdic and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-04 with Medical categories.
Within the healthcare domain, big data is defined as any ``high volume, high diversity biological, clinical, environmental, and lifestyle information collected from single individuals to large cohorts, in relation to their health and wellness status, at one or several time points.'' Such data is crucial because within it lies vast amounts of invaluable information that could potentially change a patient's life, opening doors to alternate therapies, drugs, and diagnostic tools. Signal Processing and Machine Learning for Biomedical Big Data thus discusses modalities; the numerous ways in which this data is captured via sensors; and various sample rates and dimensionalities. Capturing, analyzing, storing, and visualizing such massive data has required new shifts in signal processing paradigms and new ways of combining signal processing with machine learning tools. This book covers several of these aspects in two ways: firstly, through theoretical signal processing chapters where tools aimed at big data (be it biomedical or otherwise) are described; and, secondly, through application-driven chapters focusing on existing applications of signal processing and machine learning for big biomedical data. This text aimed at the curious researcher working in the field, as well as undergraduate and graduate students eager to learn how signal processing can help with big data analysis. It is the hope of Drs. Sejdic and Falk that this book will bring together signal processing and machine learning researchers to unlock existing bottlenecks within the healthcare field, thereby improving patient quality-of-life. Provides an overview of recent state-of-the-art signal processing and machine learning algorithms for biomedical big data, including applications in the neuroimaging, cardiac, retinal, genomic, sleep, patient outcome prediction, critical care, and rehabilitation domains. Provides contributed chapters from world leaders in the fields of big data and signal processing, covering topics such as data quality, data compression, statistical and graph signal processing techniques, and deep learning and their applications within the biomedical sphere. This book’s material covers how expert domain knowledge can be used to advance signal processing and machine learning for biomedical big data applications.