Genomics In Endocrinology
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Genomics In Endocrinology
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Author : Stuart Handwerger
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-26
Genomics In Endocrinology written by Stuart Handwerger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-26 with Medical categories.
In recent years, the development of new technologies capable of monitoring genome function has resulted in fewer hopeful estimates and increasingly solid depictions of genome output from individual samples. Genomics in Endocrinology focuses on exciting new advances in endocrinology resulting from DNA microarray studies and includes a comprehensive introduction to the use of DNA microarrays in endocrinology. The volume provides the basis for further understanding of the usefulness of microarray analyses in endocrinology research. Topics discussed are the methodology of DNA microarrays and general methods for the analysis of microarray data, as well as studies of a wide variety of normal and abnormal endocrine cells. In the introductory chapter, the volume’s editors describe several issues in hypothesis formulation, experimental design, data analysis, and follow-up studies that may corroborate, validate, and extend hypotheses gained through microarray analyses. The contributed chapters span a variety of applications that we have divided into the areas of (1) genomic insights into molecular mechanisms responsible for hormone action, (2) genomic characterizations of endocrine producing tissues, and (3) genomic manifestations of diseases of hormonal systems. A volume on the cutting-edge of technology, Genomics in Endocrinology will provide researchers with an authoritative volume on the most recent advances in monitoring genome function.
Endocrinology E Book
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Author : J. Larry Jameson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2010-05-18
Endocrinology E Book written by J. Larry Jameson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-18 with Medical categories.
ENDOCRINOLOGY, edited by J. Larry Jameson, MD, PhD and Leslie J. De Groot, MD, has been considered the definitive source in its field for decades. Now this landmark reference has been exhaustively updated to bring you the latest clinical guidance on all aspects of diagnosis and treatment for the full range of endocrine and metabolism disorders, including new information on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors. Entirely new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis keep you well informed on today’s hot topics. You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. This reference is optimally designed to help you succeed in your demanding practice and ensure the best possible outcomes for every patient. Overcome virtually any clinical challenge with detailed, expert coverage of every area of endocrinology, authored by hundreds of leading luminaries in the field. Provide state-of-the-art care with comprehensive updates on diabetes, obesity, MEN I and II, disorders of sex determination, and pituitary tumors ... brand-new chapters on Lipodystrophy Syndromes, Lipoprotein Metabolism, and Genetic Disorders of Phosphate Homeostasis ... expanded coverage of sports performance, including testosterone, androgen research, and bone growth and deterioration ... and the newest discoveries in genetics and how they affect patient care. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion. Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information more quickly, while still getting the complete coverage you expect.
Genetics In Endocrinology
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Author : John D. Baxter
language : en
Publisher: Lippincott Raven
Release Date : 2002
Genetics In Endocrinology written by John D. Baxter and has been published by Lippincott Raven this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
An extensive body of evidence highlights the crucial importance of endocrine genetics. Examples range from human growth disorders and obesity to cancers of the prostate and breast. A pivotal part of the Modern Endocrinology Series, this book presents major biological studies underlining the significance of data obtained from knock-out mice, as well as from transgenic animals. Gene therapy and laboratory evaluation and screening of genetic endocrine diseases are covered, as are many of the classical endocrine diseases.
Endocrinology Adult And Pediatric E Book
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Author : J. Larry Jameson
language : en
Publisher: Elsevier Health Sciences
Release Date : 2015-02-25
Endocrinology Adult And Pediatric E Book written by J. Larry Jameson and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.
Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Mammalian Endocrinology And Male Reproductive Biology
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Author : Shio Kumar Singh
language : en
Publisher: CRC Press
Release Date : 2015-09-04
Mammalian Endocrinology And Male Reproductive Biology written by Shio Kumar Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-04 with Medical categories.
Mammalian Endocrinology and Male Reproductive Biology provides comprehensive and current coverage of the area of endocrinology and male reproductive biology, covering not just humans, but mammals in general. Written by international experts in their respective fields, this multi-author book also covers the latest developments in genomics of androge
Genomics Proteomics And Metabolomics
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Author : Babak Arjmand
language : en
Publisher: Springer Nature
Release Date : 2019-11-14
Genomics Proteomics And Metabolomics written by Babak Arjmand and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Science categories.
This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine. Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.
Genomic Medicine The Genetic Information Revolution In Clinical Practice
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :
Genomic Medicine The Genetic Information Revolution In Clinical Practice written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Health & Fitness categories.
Welcome to the world of genomics and its incredible applications in medicine. In this book, we will explore the scientific and technological advances that have revolutionized our understanding of the human genome and how these discoveries are transforming the field of health. Genomics, which studies the structure, function and sequence of our genetic material, has played a fundamental role in the identification of genetic variants associated with diseases and in the development of new therapeutic strategies. By mapping the human genome, it has become possible to better understand the origins of diseases and offer personalized treatments, opening doors to precision medicine. In this book, we'll delve into a number of fascinating and interconnected topics. We'll start by exploring gene therapy, an innovative approach that aims to correct genetic defects directly at the DNA level. We will see how genomics has the potential to transform the landscape of dentistry, revealing valuable information about oral health and contributing to more effective treatments. In addition, we will examine the interface between genomics and regulatory medicine, considering the ethical and social implications of genomic discoveries. We will also explore the role of genomics in mental health, seeking to identify genetic markers that may aid in the diagnosis and treatment of psychiatric disorders. Genomics has a significant impact on personalized medicine, and we will discuss its applications in a variety of diseases, from pediatric infectious diseases to metabolic and endocrine diseases. Furthermore, we will investigate its role in addressing chronic, rare and genetic diseases in children. As we move forward, we will also explore genomics in emerging areas such as nanomedicine, precision medicine in developing countries, and synthetic biology. We will investigate its influence in the field of obstetrics, stem cells, genetic engineering, neurodegenerative diseases, urological diseases and aging. By the end of this book, I hope you will have a deeper understanding of the vast possibilities offered by genomics in the search for more effective, personalized and well-being treatments for each individual. Genomics is transforming medicine as we know it, and it is an ever-evolving field filled with promise and exciting discoveries. Ready to embark on this fascinating journey? Let's explore together the secrets of the human genome and its implications for the health and well-being of humanity.
Evidence Based Endocrinology
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Author : Camacho
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2012
Evidence Based Endocrinology written by Camacho and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
This pocket-sized quick-reference handbook presents evidence-based recommendations for diagnosis and treatment of endocrine disorders. The authors summarize the latest and best clinical studies supporting the practice recommendations and grade each study to indicate the benefits and risks of the therapy and the reliability of the study results. Chapters cover disorders in the major areas of endocrinology--hypothalamic-pituitary, thyroid, adrenal, metabolic bone, reproductive, diabetes, lipid disorders, obesity and nutrition, endocrine malignancies, and genetics.
Transgenic Models In Endocrinology
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Author : Maria G. Castro
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Transgenic Models In Endocrinology written by Maria G. Castro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The dramatic recent expansion in genomic information has motivated the development of new approaches to characterize gene expression and function. A critical issue for both basic and clinical endocrinologists is the physiological role of genes involved in regulating endocrine functions. Transgenic technologies allow the translation of genotypic information into specific phenotypes by using gene overexpression or loss of specific gene functions. Murine functional genomics is thus of central importance in modem biomedical endocrine research. Although mice are at present, the preferred mammalian species for genetic manipulations because of the availability of pluripotent embryonic. stem cells and inbred strains and the relatively low breeding and maintenance costs, transgenic rats have also been generated and used to study endocrine physiology. The two basic techniques used in the creation of transgenic animal models are integration of foreign DNA into a fertilized oocyte by random chromosomal insertion and homologous recombination in embryonic stem cells that are then introduced into zygotes. Transgenic mice and rats serve as sophisticted tools to probe protein function, as models of human disease, and as hosts for the testing of gene replacement and other therapies. Embryonic stem cell libraries for mouse gene deletion are being developed, which will make it possible to generate knockout mice rapidly and without the need to analyze gene structure, construct targeting vectors, and screen embryonic stem cell clones. A novel approach to transgenesis for the expression of DNA within adult differentiated neuroendocrine cells in vivo is using viral vectors.
Practical Endocrinology And Diabetes In Children
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Author : Malcolm D. C. Donaldson
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-15
Practical Endocrinology And Diabetes In Children written by Malcolm D. C. Donaldson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Medical categories.
The revised and updated fourth edition of Practical Endocrinology and Diabetes in Children offers a practical, highly clinical and up-to-date handbook of paediatric endocrinology and diabetes. The book is written in clear terms and offers a user-friendly format that is designed to be concise, yet comprehensive.. The international panel of expert contributors explore the range of endocrine disorders in children including growth, thyroid, adrenal and problems related to puberty.